Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture AM Paşca, SA Sloan, LE Clarke, Y Tian, CD Makinson, N Huber, CH Kim, ... Nature methods 12 (7), 671-678, 2015 | 760 | 2015 |
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome SP Paşca, T Portmann, I Voineagu, M Yazawa, A Shcheglovitov, ... Nature medicine 17 (12), 1657, 2011 | 503 | 2011 |
Assembly of functionally integrated human forebrain spheroids F Birey, J Andersen, CD Makinson, S Islam, W Wei, N Huber, HC Fan, ... Nature 545 (7652), 54-59, 2017 | 491 | 2017 |
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain BE Deverman, PL Pravdo, BP Simpson, SR Kumar, KY Chan, A Banerjee, ... Nature biotechnology 34 (2), 204-209, 2016 | 469 | 2016 |
Human astrocyte maturation captured in 3D cerebral cortical spheroids derived from pluripotent stem cells SA Sloan, S Darmanis, N Huber, TA Khan, F Birey, C Caneda, R Reimer, ... Neuron 95 (4), 779-790. e6, 2017 | 234 | 2017 |
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons JF Krey, SP Paşca, A Shcheglovitov, M Yazawa, R Schwemberger, ... Nature neuroscience 16 (2), 201-209, 2013 | 205 | 2013 |
The rise of three-dimensional human brain cultures SP Pașca Nature 553 (7689), 437-445, 2018 | 203 | 2018 |
High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism SP Paşca, B Nemeş, L Vlase, CE Gagyi, E Dronca, AC Miu, M Dronca Life sciences 78 (19), 2244-2248, 2006 | 162 | 2006 |
Building models of brain disorders with three-dimensional organoids ND Amin, SP Paşca Neuron 100 (2), 389-405, 2018 | 141 | 2018 |
Reliability of human cortical organoid generation SJ Yoon, LS Elahi, AM Pașca, RM Marton, A Gordon, O Revah, Y Miura, ... Nature methods 16 (1), 75-78, 2019 | 133 | 2019 |
One carbon metabolism disturbances and the C677T MTHFR gene polymorphism in children with autism spectrum disorders SP Paşca, E Dronca, T Kaucsár, EC Crǎciun, E Endreffy, BK Ferencz, ... Journal of cellular and molecular medicine 13 (10), 4229-4238, 2009 | 118 | 2009 |
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures RM Marton, Y Miura, SA Sloan, Q Li, O Revah, RJ Levy, JR Huguenard, ... Nature neuroscience 22 (3), 484-491, 2019 | 105 | 2019 |
Engineered materials for organoid systems MJ Kratochvil, AJ Seymour, TL Li, SP Paşca, CJ Kuo, SC Heilshorn Nature Reviews Materials 4 (9), 606-622, 2019 | 89 | 2019 |
The ethics of experimenting with human brain tissue NA Farahany, HT Greely, S Hyman, C Koch, C Grady, SP Pașca, ... Nature 556 (7702), 429-432, 2018 | 82 | 2018 |
Nondestructive nanostraw intracellular sampling for longitudinal cell monitoring Y Cao, M Hjort, H Chen, F Birey, SA Leal-Ortiz, CM Han, JG Santiago, ... Proceedings of the National Academy of Sciences 114 (10), E1866-E1874, 2017 | 79 | 2017 |
Generation and assembly of human brain region–specific three-dimensional cultures SA Sloan, J Andersen, AM Pașca, F Birey, SP Pașca Nature protocols 13 (9), 2062-2085, 2018 | 77 | 2018 |
A deleterious Nav1. 1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients Y Sun, SP Paşca, T Portmann, C Goold, KA Worringer, W Guan, KC Chan, ... elife 5, e13073, 2016 | 75 | 2016 |
Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome Y Tian, I Voineagu, SP Paşca, H Won, V Chandran, S Horvath, ... Genome medicine 6 (10), 1-16, 2014 | 67 | 2014 |
Generating human neurons in vitro and using them to understand neuropsychiatric disease SP Paşca, G Panagiotakos, RE Dolmetsch Annual review of neuroscience 37, 479-501, 2014 | 65 | 2014 |
MicroRNA-9 couples brain neurogenesis and angiogenesis R Madelaine, SA Sloan, N Huber, JH Notwell, LC Leung, G Skariah, ... Cell reports 20 (7), 1533-1542, 2017 | 57 | 2017 |