Dahai Luo

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Julien lescarNTUVerified email at ntu.edu.sg
Wint Wint PhooDuke-NUS, Johnson and Johnson Satellite Center for Global Health DiscoveryVerified email at duke-nus.edu.sg
Anna Marie PyleSterling Professor, MCDB Yale UniversityVerified email at yale.edu
Jie ZhengResearch Associate, The Scripps Research Institute, Jupiter, USAVerified email at scripps.edu
Andrew KohlwayPostdoctoral Student, Stanford UniversityVerified email at stanford.edu
Kang CongbaoExperimental Drug Development Centre (EDDC), A*STAR, SingaporeVerified email at eddc.a-star.edu.sg
Zhang ZhenzhenNTUVerified email at ntu.edu.sg
Yaw Bia TanNanyang Technological University, Lee Kong Chian School of MedicineVerified email at e.ntu.edu.sg
Chew Bing Liang AlvinNanyang Technological UniversityVerified email at e.ntu.edu.sg
Yan LiTongji Medical College, Huazhong University of Science and TechnologyVerified email at hust.edu.cn
Pei-Yong ShiVP, Global Head of Viral Vaccines, GSKVerified email at utmb.edu
Thomas H KellerInvestment Partner, Trinity Innovation Bioventures SingaporeVerified email at trinity-fund.com
Moon Tay / Moon YF Tay / Tay MY / Ta...Research Fellow, NTU Food Technology Centre (NAFTEC), Nanyang Technological University (NTU)Verified email at ntu.edu.sg
Yee-Song LawSingapore Institute of Food and Biotechnology Innovation, ASTARVerified email at sifbi.a-star.edu.sg
Kunchithapadam SwaminathanAssociate Professor, National University of SingaporeVerified email at nus.edu.sg
Brett LindenbachYale UniversityVerified email at yale.edu
David C RawlingseqWellVerified email at seqwell.com
Jade ForwoodCharles Sturt UniversityVerified email at csu.edu.au
Eng Eong OoiDuke-NUS Medical SchoolVerified email at duke-nus.edu.sg
Michelle LawNanyang Technological University, Lee Kong Chian School of MedicineVerified email at e.ntu.edu.sg

Dahai Luo

Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore

Verified email at ntu.edu.sg - Homepage

Infection Immunity Structural Biology RNA Virus


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Structural insights into RNA recognition by RIG-I D Luo, SC Ding, A Vela, A Kohlway, BD Lindenbach, AM Pyle Cell 147 (2), 409-422, 2011	441	2011
Crystal structure of the NS3 protease-helicase from dengue virus D Luo, T Xu, C Hunke, G Gruber, SG Vasudevan, J Lescar Journal of virology 82 (1), 173-183, 2008	353	2008
The flavivirus NS2B–NS3 protease–helicase as a target for antiviral drug development D Luo, SG Vasudevan, J Lescar Antiviral research 118, 148-158, 2015	305	2015
Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein D Luo, T Xu, RP Watson, D Scherer‐Becker, A Sampath, W Jahnke, ... The EMBO journal 27 (23), 3209-3219, 2008	296	2008
Towards the design of antiviral inhibitors against flaviviruses: the case for the multifunctional NS3 protein from Dengue virus as a target J Lescar, D Luo, T Xu, A Sampath, SP Lim, B Canard, SG Vasudevan Antiviral research 80 (2), 94-101, 2008	262	2008
Structure of the NS2B-NS3 protease from Zika virus after self-cleavage WW Phoo, Y Li, Z Zhang, MY Lee, YR Loh, YB Tan, EY Ng, J Lescar, ... Nature communications 7 (1), 13410, 2016	218	2016
A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication Y Zhao, TS Soh, J Zheng, KWK Chan, WW Phoo, CC Lee, MYF Tay, ... PLoS pathogens 11 (3), e1004682, 2015	215	2015
Crystal structure of unlinked NS2B-NS3 protease from Zika virus Z Zhang, Y Li, YR Loh, WW Phoo, AW Hung, CB Kang, D Luo Science 354 (6319), 1597-1600, 2016	179	2016
Flexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications D Luo, N Wei, DN Doan, PN Paradkar, Y Chong, AD Davidson, M Kotaka, ... Journal of biological chemistry 285 (24), 18817-18827, 2010	162	2010
Quantifying the RNA cap epitranscriptome reveals novel caps in cellular and viral RNA J Wang, BL Alvin Chew, Y Lai, H Dong, L Xu, S Balamkundu, WM Cai, ... Nucleic acids research 47 (20), e130-e130, 2019	139	2019
The C-terminal 50 amino acid residues of dengue NS3 protein are important for NS3-NS5 interaction and viral replication MYF Tay, WG Saw, Y Zhao, KWK Chan, D Singh, Y Chong, JK Forwood, ... Journal of Biological Chemistry 290 (4), 2379-2394, 2015	135	2015
Defining the functional determinants for RNA surveillance by RIG‐I A Kohlway, D Luo, DC Rawling, SC Ding, AM Pyle EMBO reports 14 (9), 772-779, 2013	127	2013
The hexamer structure of the Rift Valley fever virus nucleoprotein suggests a mechanism for its assembly into ribonucleoprotein complexes F Ferron, Z Li, EI Danek, D Luo, Y Wong, B Coutard, V Lantez, R Charrel, ... PLoS pathogens 7 (5), e1002030, 2011	121	2011
Structural dynamics of Zika virus NS2B-NS3 protease binding to dipeptide inhibitors Y Li, Z Zhang, WW Phoo, YR Loh, W Wang, S Liu, MW Chen, AW Hung, ... Structure 25 (8), 1242-1250. e3, 2017	110	2017
Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin M Peng, S Watanabe, KWK Chan, Q He, Y Zhao, Z Zhang, X Lai, D Luo, ... Antiviral Research 143, 176-185, 2017	110	2017
Zika virus protease: an antiviral drug target CB Kang, TH Keller, D Luo Trends in microbiology 25 (10), 797-808, 2017	102	2017
Structure-based mutational analysis of the NS3 helicase from dengue virus A Sampath, T Xu, A Chao, D Luo, J Lescar, SG Vasudevan Journal of virology 80 (13), 6686-6690, 2006	95	2006
Molecular basis for specific viral RNA recognition and 2′-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) Y Zhao, TS Soh, SP Lim, KY Chung, K Swaminathan, SG Vasudevan, ... Proceedings of the National Academy of Sciences 112 (48), 14834-14839, 2015	94	2015
Visualizing the determinants of viral RNA recognition by innate immune sensor RIG-I D Luo, A Kohlway, A Vela, AM Pyle Structure 20 (11), 1983-1988, 2012	89	2012
The C-terminal 18 amino acid region of dengue virus NS5 regulates its subcellular localization and contains a conserved arginine residue essential for infectious virus production MYF Tay, K Smith, IHW Ng, KWK Chan, Y Zhao, EE Ooi, J Lescar, D Luo, ... PLoS pathogens 12 (9), e1005886, 2016	84	2016

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