| Efficient mitochondrial genome editing by CRISPR/Cas9 A Jo, S Ham, GH Lee, YI Lee, SS Kim, YS Lee, JH Shin, Y Lee BioMed research international 2015, 2015 | 215 | 2015 |
| PINK1 primes Parkin-mediated ubiquitination of PARIS in dopaminergic neuronal survival Y Lee, DA Stevens, SU Kang, H Jiang, YI Lee, HS Ko, LA Scarffe, ... Cell reports 18 (4), 918-932, 2017 | 180 | 2017 |
| α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism SP Yun, D Kim, S Kim, SM Kim, SS Karuppagounder, SH Kwon, S Lee, ... Molecular neurodegeneration 13, 1-19, 2018 | 84 | 2018 |
| Activation of the ATF2/CREB-PGC-1α pathway by metformin leads to dopaminergic neuroprotection H Kang, R Khang, S Ham, GR Jeong, H Kim, M Jo, BD Lee, YI Lee, A Jo, ... Oncotarget 8 (30), 48603, 2017 | 63 | 2017 |
| PARIS farnesylation prevents neurodegeneration in models of Parkinson’s disease A Jo, Y Lee, TI Kam, SU Kang, S Neifert, SS Karuppagounder, R Khang, ... Science translational medicine 13 (604), eaax8891, 2021 | 39 | 2021 |
| Hydrocortisone-induced parkin prevents dopaminergic cell death via CREB pathway in Parkinson’s disease model S Ham, YI Lee, M Jo, H Kim, H Kang, A Jo, GH Lee, YJ Mo, SC Park, ... Scientific reports 7 (1), 525, 2017 | 39 | 2017 |
| TTC3 contributes to TGF-β1-induced epithelial−mesenchymal transition and myofibroblast differentiation, potentially through SMURF2 ubiquitylation and degradation JH Kim, S Ham, Y Lee, GY Suh, YS Lee Cell Death & Disease 10 (2), 92, 2019 | 35 | 2019 |
| CRISPR-Cas9 mediated telomere removal leads to mitochondrial stress and protein aggregation H Kim, S Ham, M Jo, GH Lee, YS Lee, JH Shin, Y Lee International journal of molecular sciences 18 (10), 2093, 2017 | 30 | 2017 |
| Ca2+-permeable TRPV1 pain receptor knockout rescues memory deficits and reduces amyloid-β and tau in a mouse model of Alzheimer’s disease J Kim, S Lee, J Kim, S Ham, JHY Park, S Han, YK Jung, I Shim, JS Han, ... Human Molecular Genetics 29 (2), 228-237, 2020 | 26 | 2020 |
| VPS35 regulates parkin substrate AIMP2 toxicity by facilitating lysosomal clearance of AIMP2 SP Yun, H Kim, S Ham, SH Kwon, GH Lee, JH Shin, SH Lee, HS Ko, ... Cell Death & Disease 8 (4), e2741-e2741, 2017 | 25 | 2017 |
| Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons S Hwang, S Ham, SE Lee, Y Lee, GH Lee Neurotoxicology 65, 221-230, 2018 | 17 | 2018 |
| Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion S Ham, SP Yun, H Kim, D Kim, BA Seo, H Kim, JY Shin, MA Dar, GH Lee, ... Science translational medicine 12 (569), eaax0091, 2020 | 16 | 2020 |
| Estrogen receptor activation contributes to RNF146 expression and neuroprotection in Parkinson's disease models H Kim, S Ham, JY Lee, A Jo, GH Lee, YS Lee, ML Cho, HM Shin, D Kim, ... Oncotarget 8 (63), 106721, 2017 | 14 | 2017 |
| CRISPR/Cas9-mediated knockout of Mct8 reveals a functional involvement of Mct8 in testis and sperm development in a rat HS Bae, YK Jin, S Ham, HK Kim, H Shin, G Cho, KJ Lee, H Lee, KM Kim, ... Scientific reports 10 (1), 11148, 2020 | 7 | 2020 |
| Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson’s Disease S Ham, H Kim, JH Yoon, H Kim, BR Song, JY Choi, YS Lee, SM Paek, ... International Journal of Molecular Sciences 20 (21), 5481, 2019 | 7 | 2019 |
| Cell-based screen using amyloid mimic β23 expression identifies peucedanocoumarin III as a novel inhibitor of α-synuclein and Huntingtin aggregates S Ham, H Kim, S Hwang, H Kang, SP Yun, S Kim, D Kim, HS Kwon, ... Molecules and cells 42 (6), 480-494, 2019 | 4 | 2019 |
| Pharmacological inhibition of aimp2 aggregation attenuates α-synuclein aggregation and toxicity in Parkinson’s disease JY Shin, B Lee, S Ham, JH Kim, H Kim, H Kim, MG Jo, HJ Kim, SW Park, ... Biomedicine & Pharmacotherapy 156, 113908, 2022 | 3 | 2022 |
| ATF4-activated parkin induction contributes to deferasirox-mediated cytoprotection in Parkinson’s disease S Ham, JH Kim, H Kim, JY Shin, Y Lee Toxicological Research 39 (2), 191-199, 2023 | 1 | 2023 |
Hanseok KoProfessor of Neurology and ICE, Johns Hopkins School of MedicineVerified email at jhmi.edu
