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Billy Wai-Lung Ng
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Coronavirus RNA proofreading: molecular basis and therapeutic targeting
F Robson, KS Khan, TK Le, C Paris, S Demirbag, P Barfuss, P Rocchi, ...
Molecular Cell, 2020
4412020
Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity
TH Wright, BJ Bower, JM Chalker, GJL Bernardes, R Wiewiora, WL Ng, ...
Science 354 (6312), aag1465, 2016
2652016
In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma
F Li, Q Huang, TA Luster, H Hu, H Zhang, WL Ng, A Khodadadi-Jamayran, ...
Cancer Discovery 10 (2), 270-287, 2020
1362020
Selective radical trifluoromethylation of native residues in proteins
M Imiołek, G Karunanithy, WL Ng, AJ Baldwin, V Gouverneur, BG Davis
Journal of the American Chemical Society 140 (5), 1568-1571, 2018
1112018
Simeprevir potently suppresses SARS-CoV-2 replication and synergizes with remdesivir
HS Lo, KPY Hui, HM Lai, X He, KS Khan, S Kaur, J Huang, Z Li, ...
ACS Central Science 7 (5), 792-802, 2021
802021
Pharmacologically reversible zonation-dependent endothelial cell transcriptomic changes with neurodegenerative disease associations in the aged brain
L Zhao, Z Li, JSL Vong, X Chen, HM Lai, LYC Yan, J Huang, SKH Sy, ...
Nature Communications 11 (1), 1-15, 2020
632020
Famotidine inhibits Toll-like receptor 3-mediated inflammatory signaling in SARS-CoV2 infection
R Mukherjee, A Bhattacharya, D Bojkova, AR Mehdipour, D Shin, ...
Journal of Biological Chemistry, 100925, 2021
502021
Nucleic acid-based technologies targeting coronaviruses
TK Le, C Paris, KS Khan, F Robson, WL Ng, P Rocchi
Trends in Biochemical Sciences, 2020
462020
Chemical probes for visualizing intact animal and human brain tissue
HM Lai, WL Ng, SM Gentleman, W Wu
Cell chemical biology 24 (6), 659-672, 2017
402017
Rationalisation and validation of an acrylamide-free procedure in three-dimensional histological imaging
HM Lai, AKL Liu, WL Ng, J DeFelice, WS Lee, H Li, W Li, HM Ng, ...
PloS one 11 (6), e0158628, 2016
392016
Phase separation in viral infections
H Li, C Ernst, M Kolonko-Adamska, B Greb-Markiewicz, J Man, V Parissi, ...
Trends in Microbiology, 2022
312022
Post-translational site-selective protein backbone α-deuteration
SRG Galan, JR Wickens, J Dadova, WL Ng, X Zhang, RA Simion, ...
Nature chemical biology 14 (10), 955, 2018
312018
Carbocyclization of d-glucose: syntheses of gabosine I and streptol
TKM Shing, Y Chen, WL Ng
Tetrahedron 67 (33), 6001-6005, 2011
242011
Short and Efficient Syntheses of Gabosine I, Streptol, 7-O-Acetylstreptol, 1-epi-Streptol, Gabosine K, and Carba-α-d-glucose from δ-d-Gluconolactone
TKM Shing, Y Chen, WL Ng
Synlett 2011 (09), 1318-1320, 2011
232011
Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer
F Li, WL Ng, TA Luster, H Hu, VO Sviderskiy, CM Dowling, ...
Cancer Research, 2020
212020
Design, Syntheses, and SAR Studies of Carbocyclic Analogues of Sergliflozin as Potent Sodium‐Dependent Glucose Cotransporter 2 Inhibitors
TKM Shing, WL Ng, JYW Chan, CBS Lau
Angewandte Chemie International Edition 52 (32), 8401-8405, 2013
212013
Loss of TSC1/TSC2 sensitizes immune checkpoint blockade in non–small cell lung cancer
Q Huang, F Li, H Hu, Z Fang, Z Gao, G Xia, WL Ng, ...
Science Advances 8 (5), eabi9533, 2022
192022
Concise and Stereodivergent Synthesis of Carbasugars Reveals Unexpected Structure-Activity Relationship (SAR) of SGLT2 Inhibition
WL Ng, HC Li, KM Lau, AKN Chan, C Bik-San Lau, TKM Shing
Scientific Reports 7 (1), 5581, 2017
192017
Residue-Selective Protein C-Formylation via Sequential Difluoroalkylation-Hydrolysis
M Imiołek, PG Isenegger, WL Ng, A Khan, V Gouverneur, BG Davis
ACS central science 7 (1), 145-155, 2021
172021
Development of Alkylated Hydrazides as Highly Potent and Selective Class I Histone Deacetylase Inhibitors with T cell Modulatory Properties
P Sun, J Wang, KS Khan, W Yang, BWL Ng, N Ilment, M Zessin, ...
Journal of Medicinal Chemistry, 2022
102022
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