The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2 GM Delgoffe, KN Pollizzi, AT Waickman, E Heikamp, DJ Meyers, ... Nature immunology 12 (4), 295-303, 2011 | 1189 | 2011 |
Regulation of immune responses by mTOR JD Powell, KN Pollizzi, EB Heikamp, MR Horton Annual review of immunology 30, 39, 2012 | 902 | 2012 |
Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization DJ Nolan, A Ciarrocchi, AS Mellick, JS Jaggi, K Bambino, S Gupta, ... Genes & development 21 (12), 1546-1558, 2007 | 504 | 2007 |
New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes H Sheldon, E Heikamp, H Turley, R Dragovic, P Thomas, CE Oon, R Leek, ... Blood, The Journal of the American Society of Hematology 116 (13), 2385-2394, 2010 | 447 | 2010 |
Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo JL Li, RCA Sainson, W Shi, R Leek, LS Harrington, M Preusser, S Biswas, ... Cancer research 67 (23), 11244-11253, 2007 | 406 | 2007 |
The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex EB Heikamp, CH Patel, S Collins, A Waickman, MH Oh, IH Sun, P Illei, ... Nature immunology 15 (5), 457-464, 2014 | 192 | 2014 |
Large DNA methylation nadirs anchor chromatin loops maintaining hematopoietic stem cell identity X Zhang, M Jeong, X Huang, XQ Wang, X Wang, W Zhou, MS Shamim, ... Molecular cell 78 (3), 506-521. e6, 2020 | 71 | 2020 |
The menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML EB Heikamp, JA Henrich, F Perner, EM Wong, C Hatton, Y Wen, ... Blood, The Journal of the American Society of Hematology 139 (6), 894-906, 2022 | 63 | 2022 |
Next-generation evaluation and treatment of pediatric acute lymphoblastic leukemia EB Heikamp, CH Pui The Journal of pediatrics 203, 14-24. e2, 2018 | 51 | 2018 |
Multiple, conserved cryptic recombination signals in VH gene segments: detection of cleavage products only in pro–B cells M Davila, F Liu, LG Cowell, AE Lieberman, E Heikamp, A Patel, G Kelsoe The Journal of experimental medicine 204 (13), 3195-3208, 2007 | 38 | 2007 |
A modified model of T-cell differentiation based on mTOR activity and metabolism JD Powell, EB Heikamp, KN Pollizzi, AT Waickman Cold Spring Harbor symposia on quantitative biology 78, 125-130, 2013 | 32 | 2013 |
Sensing the immune microenvironment to coordinate T cell metabolism, differentiation & function EB Heikamp, JD Powell Seminars in immunology 24 (6), 414-420, 2012 | 26 | 2012 |
The mammalian Target of Rapamycin (mTOR) regulates T helper cell differentiation through the selective activation of mTORC1 and mTORC2 signaling GM Delgoffe, KN Pollizzi, AT Waickman, E Heikamp, DJ Meyers, ... Nature immunology 12 (4), 295, 2011 | 22 | 2011 |
Regulation of T cell differentiation and function by mTOR J Powell, G Delgoffe, K Pollizzi, E Heikamp, A Waickman IMMUNOLOGY 135, 4-4, 2011 | | 2011 |