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Thomas M Tomasiak
Thomas M Tomasiak
Assistant Professor of Chemistry and Biochemistry, University of Arizona
Bestätigte E-Mail-Adresse bei email.arizona.edu
Titel
Zitiert von
Zitiert von
Jahr
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer
BC Monk, TM Tomasiak, MV Keniya, FU Huschmann, JDA Tyndall, ...
Proceedings of the National Academy of Sciences 111 (10), 3865-3870, 2014
2872014
Subnanometre-resolution electron cryomicroscopy structure of a heterodimeric ABC exporter
JM Kim, S Wu, TM Tomasiak, C Mergel, MB Winter, SB Stiller, ...
Nature 517 (7534), 396-400, 2015
1272015
A structural model for binding of the serine-rich repeat adhesin GspB to host carbohydrate receptors
TM Pyburn, BA Bensing, YQ Xiong, BJ Melancon, TM Tomasiak, NJ Ward, ...
PLoS pathogens 7 (7), e1002112, 2011
1042011
Crystal structure and mechanistic basis of a functional homolog of the antigen transporter TAP
A Nöll, C Thomas, V Herbring, T Zollmann, K Barth, AR Mehdipour, ...
Proceedings of the National Academy of Sciences 114 (4), E438-E447, 2017
852017
Indole-3-carbinol (I3C) analogues are potent small molecule inhibitors of NEDD4-1 ubiquitin ligase activity that disrupt proliferation of human melanoma cells
JG Quirit, SN Lavrenov, K Poindexter, J Xu, C Kyauk, KA Durkin, ...
Biochemical pharmacology 127, 13-27, 2017
692017
A threonine on the active site loop controls transition state formation in Escherichia coli respiratory complex II
TM Tomasiak, E Maklashina, G Cecchini, TM Iverson
Journal of Biological Chemistry 283 (22), 15460-15468, 2008
322008
The structural basis for regulation of the glutathione transporter Ycf1 by regulatory domain phosphorylation
NK Khandelwal, CR Millan, SI Zangari, S Avila, D Williams, TM Thaker, ...
Nature Communications 13 (1), 1278, 2022
262022
Geometric restraint drives on-and off-pathway catalysis by the Escherichia coli menaquinol: fumarate reductase
TM Tomasiak, TL Archuleta, J Andréll, C Luna-Chávez, TA Davis, ...
Journal of Biological Chemistry 286 (4), 3047-3056, 2011
242011
Asymmetric drug binding in an ATP-loaded inward-facing state of an ABC transporter
TM Thaker, S Mishra, W Zhou, M Mohan, Q Tang, JD Faraldo-Goméz, ...
Nature chemical biology 18 (2), 226-235, 2022
202022
General qPCR and plate reader methods for rapid optimization of membrane protein purification and crystallization using thermostability assays
TM Tomasiak, BP Pedersen, S Chaudhary, A Rodriguez, YR Colmanares, ...
Current Protocols in Protein Science 77 (1), 29.11. 1-29.11. 14, 2014
182014
Plasticity of the quinone-binding site of the complex II homolog quinol: fumarate reductase
PK Singh, M Sarwar, E Maklashina, V Kotlyar, S Rajagukguk, ...
Journal of Biological Chemistry 288 (34), 24293-24301, 2013
112013
Succinate as donor; fumarate as acceptor
TM Tomasiak, G Cecchini, TM Iverson
EcoSal Plus 2 (2), 10.1128/ecosal. 3.2. 6, 2007
102007
Vaccines to prevent coccidioidomycosis: a gene-deletion mutant of Coccidioides posadasii as a viable candidate for human trials
JN Galgiani, LF Shubitz, MJ Orbach, MA Mandel, DA Powell, BS Klein, ...
Journal of Fungi 8 (8), 838, 2022
92022
New crystal forms of the integral membrane Escherichia coli quinol: fumarate reductase suggest that ligands control domain movement
CA Starbird, TM Tomasiak, PK Singh, V Yankovskaya, E Maklashina, ...
Journal of structural biology 202 (1), 100-104, 2018
92018
A conserved motif in intracellular loop 1 stabilizes the outward-facing conformation of TmrAB
CR Millan, M Francis, NK Khandelwal, VF Thompson, TM Thaker, ...
Journal of molecular biology 433 (16), 166834, 2021
72021
’Connell JD, Cannon RD, McDonald JG, Rodriguez A, Finer-Moore JS, Stroud RM. Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the …
BC Monk, TM Tomasiak, MV Keniya, FU Huschmann, O Tyndall JDa
Proc Natl Acad Sci US A 111, 3865-70, 2014
72014
Copper-Catalyzed Decarboxylative N-Arylation of Indole-2-carboxylic Acids
Y Zhang, ZY Hu, XC Li, XX Guo
Synthesis 51 (08), 1803-1808, 2019
62019
Subnanometer resolution cryo-EM structure of a nucleotide free heterodimeric ABC exporter
JM Kim, S Wu, T Tomasiak, C Mergel, MB Winter, SB Stiller, ...
Nature 517 (7534), 396, 2015
52015
Structural basis for autoinhibition by the dephosphorylated regulatory domain of Ycf1
NK Khandelwal, TM Tomasiak
Nature Communications 15 (1), 2389, 2024
32024
The role of novel COQ8B mutations in glomerulopathy and related kidney defects
AS AbuMaziad, TM Thaker, TM Tomasiak, CC Chong, MK Galindo, ...
American Journal of Medical Genetics Part A 185 (1), 60-67, 2021
32021
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