Tomas Björklund
Tomas Björklund
Professor of Neuroscience, Wallenberg Neuroscience Center, Lund University, Sweden
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Zitiert von
Zitiert von
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats
S Holmqvist, O Chutna, L Bousset, P Aldrin-Kirk, W Li, T Björklund, ...
Acta neuropathologica 128, 805-820, 2014
A general chemical method to regulate protein stability in the mammalian central nervous system
M Iwamoto, T Björklund, C Lundberg, D Kirik, TJ Wandless
Chemistry & biology 17 (9), 981-988, 2010
Long-term consequences of human alpha-synuclein overexpression in the primate ventral midbrain
A Eslamboli, M Romero-Ramos, C Burger, T Bjorklund, N Muzyczka, ...
Brain 130 (3), 799-815, 2007
Applications of lentiviral vectors for biology and gene therapy of neurological disorders
C Lundberg, T Bjorklund, T Carlsson, J Jakobsson, P Hantraye, N Déglon, ...
Current gene therapy 8 (6), 461-473, 2008
A systematic capsid evolution approach performed in vivo for the design of AAV vectors with tailored properties and tropism
M Davidsson, G Wang, P Aldrin-Kirk, T Cardoso, S Nolbrant, M Hartnor, ...
Proceedings of the National Academy of Sciences 116 (52), 27053-27062, 2019
Mutant huntingtin causes metabolic imbalance by disruption of hypothalamic neurocircuits
S Hult, R Soylu, T Björklund, BF Belgardt, J Mauer, JC Brüning, D Kirik, ...
Cell metabolism 13 (4), 428-439, 2011
Differential transduction following basal ganglia administration of distinct pseudotyped AAV capsid serotypes in nonhuman primates
HB Dodiya, T Bjorklund, J Stansell III, RJ Mandel, D Kirik, JH Kordower
Molecular Therapy 18 (3), 579-587, 2010
A novel adeno-associated virus capsid with enhanced neurotropism corrects a lysosomal transmembrane enzyme deficiency
J Tordo, C O’Leary, ASLM Antunes, N Palomar, P Aldrin-Kirk, M Basche, ...
Brain 141 (7), 2014-2031, 2018
Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons
A Ulusoy, G Sahin, T Björklund, P Aebischer, D Kirik
Molecular Therapy 17 (9), 1574-1584, 2009
Cellular barcoding links B-1a B cell potential to a fetal hematopoietic stem cell state at the single-cell level
TA Kristiansen, EJ Gyllenbäck, A Zriwil, T Björklund, JA Daniel, E Sitnicka, ...
Immunity 45 (2), 346-357, 2016
Robust license plate recognition using neural networks trained on synthetic images
T Björklund, A Fiandrotti, M Annarumma, G Francini, E Magli
Pattern Recognition 93, 134-146, 2019
A novel α-synuclein-GFP mouse model displays progressive motor impairment, olfactory dysfunction and accumulation of α-synuclein-GFP
C Hansen, T Björklund, GH Petit, M Lundblad, RP Murmu, P Brundin, ...
Neurobiology of disease 56, 145-155, 2013
Gene therapy for Parkinson's disease
T Bjorklund, JH Kordower
Movement disorders 25 (S1), S161-S173, 2010
Dysregulated dopamine storage increases the vulnerability to α-synuclein in nigral neurons
A Ulusoy, T Björklund, K Buck, D Kirik
Neurobiology of disease 47 (3), 367-377, 2012
DREADD modulation of transplanted DA neurons reveals a novel parkinsonian dyskinesia mechanism mediated by the serotonin 5-HT6 receptor
P Aldrin-Kirk, A Heuer, G Wang, B Mattsson, M Lundblad, M Parmar, ...
Neuron 90 (5), 955-968, 2016
Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson’s disease
T Björklund, T Carlsson, EA Cederfjäll, M Carta, D Kirik
Brain 133 (2), 496-511, 2010
Restoration of the striatal dopamine synthesis for Parkinson's disease: viral vector-mediated enzyme replacement strategy
T Carlsson, T Bjorklund, D Kirik
Current gene therapy 7 (2), 109-120, 2007
Morphometric and psychometric comparisons between non-substance-abusing patients with posttraumatic stress disorder and normal controls
R Emdad, D Bonekamp, HP Söndergaard, T Björklund, I Agartz, M Ingvar, ...
Psychotherapy and psychosomatics 75 (2), 122-132, 2006
Scientific rationale for the development of gene therapy strategies for Parkinson's disease
T Björklund, D Kirik
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1792 (7), 703-713, 2009
A novel process of viral vector barcoding and library preparation enables high-diversity library generation and recombination-free paired-end sequencing
M Davidsson, P Diaz-Fernandez, OD Schwich, M Torroba, G Wang, ...
Scientific Reports 6 (1), 37563, 2016
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