Follow
Francesco Ortuso
Title
Cited by
Cited by
Year
Chalcones: a valid scaffold for monoamine oxidases inhibitors
F Chimenti, R Fioravanti, A Bolasco, P Chimenti, D Secci, F Rossi, ...
Journal of medicinal chemistry 52 (9), 2818-2824, 2009
2392009
Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins
F Chimenti, D Secci, A Bolasco, P Chimenti, B Bizzarri, A Granese, ...
Journal of medicinal chemistry 52 (7), 1935-1942, 2009
1852009
Synthesis and biological evaluation of N-substituted-3, 5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors
R Fioravanti, A Bolasco, F Manna, F Rossi, F Orallo, F Ortuso, S Alcaro, ...
European journal of medicinal chemistry 45 (12), 6135-6138, 2010
1662010
Chromone, a privileged scaffold for the development of monoamine oxidase inhibitors
A Gaspar, T Silva, M Yánez, D Vina, F Orallo, F Ortuso, E Uriarte, S Alcaro, ...
Journal of medicinal chemistry 54 (14), 5165-5173, 2011
1652011
Synthesis, molecular modeling studies, and selective inhibitory activity against monoamine oxidase of 1-thiocarbamoyl-3, 5-diaryl-4, 5-dihydro-(1 H)-pyrazole derivatives
F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ...
Journal of medicinal chemistry 48 (23), 7113-7122, 2005
1602005
Quercetin as the Active Principle of Hypericum hircinum Exerts a Selective Inhibitory Activity against MAO-A:  Extraction, Biological Analysis, and Computational …
F Chimenti, F Cottiglia, L Bonsignore, L Casu, M Casu, C Floris, D Secci, ...
Journal of natural products 69 (6), 945-949, 2006
1432006
A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors
F Chimenti, R Fioravanti, A Bolasco, P Chimenti, D Secci, F Rossi, ...
Bioorganic & medicinal chemistry 18 (3), 1273-1279, 2010
1282010
Inhibition of monoamine oxidases by coumarin-3-acyl derivatives: biological activity and computational study
F Chimenti, D Secci, A Bolasco, P Chimenti, A Granese, O Befani, P Turini, ...
Bioorganic & medicinal chemistry letters 14 (14), 3697-3703, 2004
1222004
Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors
A Procopio, S Alcaro, M Nardi, M Oliverio, F Ortuso, P Sacchetta, ...
Journal of agricultural and food chemistry 57 (23), 11161-11167, 2009
1202009
GBPM: GRID-based pharmacophore model: concept and application studies to protein–protein recognition
F Ortuso, T Langer, S Alcaro
Bioinformatics 22 (12), 1449-1455, 2006
1192006
Selective inhibitory activity against MAO and molecular modeling studies of 2-thiazolylhydrazone derivatives
F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ...
Journal of medicinal chemistry 50 (4), 707-712, 2007
1162007
Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives
D Secci, S Carradori, A Bolasco, P Chimenti, M Yáņez, F Ortuso, S Alcaro
European journal of medicinal chemistry 46 (10), 4846-4852, 2011
1132011
Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
F Moraca, J Amato, F Ortuso, A Artese, B Pagano, E Novellino, S Alcaro, ...
Proceedings of the National Academy of Sciences 114 (11), E2136-E2145, 2017
1092017
Synthesis, stereochemical identification, and selective inhibitory activity against human monoamine oxidase-B of 2-methylcyclohexylidene-(4-arylthiazol-2-yl) hydrazones
F Chimenti, E Maccioni, D Secci, A Bolasco, P Chimenti, A Granese, ...
Journal of medicinal chemistry 51 (16), 4874-4880, 2008
1092008
Investigations on the 2-thiazolylhydrazyne scaffold: synthesis and molecular modeling of selective human monoamine oxidase inhibitors
F Chimenti, A Bolasco, D Secci, P Chimenti, A Granese, S Carradori, ...
Bioorganic & medicinal chemistry 18 (15), 5715-5723, 2010
1072010
Homoisoflavonoids: natural scaffolds with potent and selective monoamine oxidase-B inhibition properties
N Desideri, A Bolasco, R Fioravanti, L Proietti Monaco, F Orallo, M Yáņez, ...
Journal of medicinal chemistry 54 (7), 2155-2164, 2011
1042011
Modeling and biological evaluation of 3, 3′-(1, 2-ethanediyl) bis [2-(4-methoxyphenyl)-thiazolidin-4-one], a new synthetic cyclooxygenase-2 inhibitor
R Ottaná, E Mazzon, L Dugo, F Monforte, R Maccari, L Sautebin, ...
European journal of pharmacology 448 (1), 71-80, 2002
1022002
N-myristoylation determines dual targeting of mammalian NADH-cytochrome b (5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning
S Colombo, R Longhi, S Alcaro, F Ortuso, T Sprocati, A Flora, N Borgese
The Journal of cell biology 168 (5), 735-745, 2005
1012005
Discovery of new chemical entities for old targets: insights on the lead optimization of chromone-based monoamine oxidase B (MAO-B) inhibitors
J Reis, F Cagide, D Chavarria, T Silva, C Fernandes, A Gaspar, E Uriarte, ...
Journal of Medicinal Chemistry 59 (12), 5879-5893, 2016
952016
Identification and characterization of new DNA G-quadruplex binders selected by a combination of ligand and structure-based virtual screening approaches
S Alcaro, C Musetti, S Distinto, M Casatti, G Zagotto, A Artese, L Parrotta, ...
Journal of medicinal chemistry 56 (3), 843-855, 2013
952013
The system can't perform the operation now. Try again later.
Articles 1–20