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Christopher Yau
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Genome-wide association study of CNVs in 16,000 cases of eight common diseases and 3,000 shared controls
Nature 464 (7289), 713-720, 2010
8862010
QuantiSNP: an Objective Bayes Hidden-Markov Model to detect and accurately map copy number variation using SNP genotyping data
S Colella, C Yau, JM Taylor, G Mirza, H Butler, P Clouston, AS Bassett, ...
Nucleic Acids Research 35 (6), 2013-2025, 2007
7142007
ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis
E Pierson, C Yau
Genome biology 16 (1), 1-10, 2015
5602015
On the utility of graphics cards to perform massively parallel simulation of advanced Monte Carlo methods
A Lee, C Yau, MB Giles, A Doucet, CC Holmes
Journal of Computational and Graphical Statistics 19 (4), 769-789, 2010
3592010
Factors influencing success of clinical genome sequencing across a broad spectrum of disorders
JC Taylor, HC Martin, S Lise, J Broxholme, JB Cazier, A Rimmer, ...
Nature genetics 47 (7), 717-726, 2015
3352015
Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension
SC Rivera, X Liu, AW Chan, AK Denniston, MJ Calvert, H Ashrafian, ...
The Lancet Digital Health 2 (10), e549-e560, 2020
2652020
Comparing CNV detection methods for SNP arrays
L Winchester, C Yau, J Ragoussis
Briefings in functional genomics & proteomics 8 (5), 353-366, 2009
2342009
Bayesian statistics and modelling
R van de Schoot, S Depaoli, R King, B Kramer, K Märtens, MG Tadesse, ...
Nature Reviews Methods Primers 1 (1), 1-26, 2021
1992021
pcaReduce: hierarchical clustering of single cell transcriptional profiles
J Zurauskiene, C Yau
BMC Bioinformatics 17 (140), 2016
1972016
Survival in stage II/III colorectal cancer is independently predicted by chromosomal and microsatellite instability, but not by specific driver mutations
D Mouradov, E Domingo, P Gibbs, RN Jorissen, S Li, PY Soo, L Lipton, ...
Official journal of the American College of Gastroenterology| ACG 108 (11 …, 2013
1552013
A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data
C Yau, D Mouradov, RN Jorissen, S Colella, G Mirza, G Steers, A Harris, ...
Genome biology 11 (9), R92, 2010
1532010
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden
JB Cazier, SR Rao, CM McLean, AK Walker, BJ Wright, EEM Jaeger, ...
Nature communications 5 (1), 1-13, 2014
1522014
Bayesian non‐parametric hidden Markov models with applications in genomics
C Yau, O Papaspiliopoulos, GO Roberts, C Holmes
Journal of the Royal Statistical Society: Series B (Statistical Methodology …, 2011
1372011
Presynaptic NMDARs in the hippocampus facilitate transmitter release at theta frequency
L McGuinness, C Taylor, RDT Taylor, C Yau, T Langenhan, ML Hart, ...
Neuron 68 (6), 1109-1127, 2010
1282010
Salt-inducible kinase 2 couples ovarian cancer cell metabolism with survival at the adipocyte-rich metastatic niche
F Miranda, D Mannion, S Liu, Y Zheng, LS Mangala, C Redondo, ...
Cancer cell 30 (2), 273-289, 2016
1242016
Germline mutations in PALB2, BRCA1, and RAD51C, which regulate DNA recombination repair, in patients with gastric cancer
R Sahasrabudhe, P Lott, M Bohorquez, T Toal, AP Estrada, JJ Suarez, ...
Gastroenterology 152 (5), 983-986. e6, 2017
922017
GenoSNP: a variational Bayes within-sample SNP genotyping algorithm that does not require a reference population
E Giannoulatou, C Yau, S Colella, J Ragoussis, CC Holmes
Bioinformatics 24 (19), 2209-2214, 2008
802008
The repertoire of serous ovarian cancer non-genetic heterogeneity revealed by single-cell sequencing of normal fallopian tube epithelial cells
Z Hu, M Artibani, A Alsaadi, N Wietek, M Morotti, T Shi, Z Zhong, ...
Cancer Cell 37 (2), 226-242. e7, 2020
742020
Quantification of subclonal distributions of recurrent genomic aberrations in paired pre-treatment and relapse samples from patients with B-cell chronic lymphocytic leukemia
SJL Knight, C Yau, R Clifford, AT Timbs, ES Akha, HM Dréau, A Burns, ...
Leukemia, 2012
742012
Uncovering pseudotemporal trajectories with covariates from single cell and bulk expression data
KR Campbell, C Yau
Nature Communications 9 (1), 2442, 2018
632018
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