Photothermal nanofibres enable safe engineering of therapeutic cells R Xiong, D Hua, J Van Hoeck, D Berdecka, L Léger, S De Munter, ... Nature nanotechnology 16 (11), 1281-1291, 2021 | 214 | 2021 |
Intracellular delivery of mRNA in adherent and suspension cells by vapor nanobubble photoporation L Raes, S Stremersch, JC Fraire, T Brans, G Goetgeluk, S De Munter, ... Nano-Micro Letters 12, 1-17, 2020 | 55 | 2020 |
Vapor nanobubble is the more reliable photothermal mechanism for inducing endosomal escape of siRNA without disturbing cell homeostasis JC Fraire, G Houthaeve, J Liu, L Raes, L Vermeulen, S Stremersch, ... Journal of controlled release 319, 262-275, 2020 | 55 | 2020 |
Non-viral transfection technologies for next-generation therapeutic T cell engineering L Raes, SC De Smedt, K Raemdonck, K Braeckmans Biotechnology Advances 49, 107760, 2021 | 40 | 2021 |
Gold nanoparticle-mediated photoporation enables delivery of macromolecules over a wide range of molecular weights in human CD4+ T cells L Raes, C Van Hecke, J Michiels, S Stremersch, JC Fraire, T Brans, ... Crystals 9 (8), 411, 2019 | 35 | 2019 |
Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells A Harizaj, M Wels, L Raes, S Stremersch, G Goetgeluk, T Brans, ... Advanced Functional Materials 31 (28), 2102472, 2021 | 31 | 2021 |
Fluorescence‐based quantification of messenger RNA and plasmid DNA decay kinetics in extracellular biological fluids and cell extracts H Zhang, K Rombouts, L Raes, R Xiong, SC De Smedt, K Braeckmans, ... Advanced biosystems 4 (5), 2000057, 2020 | 30 | 2020 |
Delivery of mixed-lineage kinase domain-like protein by vapor nanobubble photoporation induces necroptotic-like cell death in tumor cells L Van Hoecke, L Raes, S Stremersch, T Brans, JC Fraire, R Roelandt, ... International Journal of Molecular Sciences 20 (17), 4254, 2019 | 25 | 2019 |
Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering L Raes, M Pille, A Harizaj, G Goetgeluk, J Van Hoeck, S Stremersch, ... Molecular Therapy-Nucleic Acids 25, 696-707, 2021 | 20 | 2021 |
Photothermally triggered endosomal escape and its influence on transfection efficiency of gold-functionalized JetPEI/pDNA nanoparticles LMP Vermeulen, JC Fraire, L Raes, E De Meester, S De Keulenaer, ... International Journal of Molecular Sciences 19 (8), 2400, 2018 | 17 | 2018 |
Light triggered nanoscale biolistics for efficient intracellular delivery of functional macromolecules in mammalian cells JC Fraire, E Shaabani, M Sharifiaghdam, M Rombaut, C Hinnekens, ... Nature Communications 13 (1), 1996, 2022 | 16 | 2022 |
Phase I study of [68Ga] Ga-Anti-CD206-sdAb for PET/CT assessment of protumorigenic macrophage presence in solid tumors (MMR phase I) O Gondry, C Xavier, L Raes, J Heemskerk, N Devoogdt, H Everaert, ... Journal of Nuclear Medicine 64 (9), 1378-1384, 2023 | 11 | 2023 |
Engineering and crystal structure of a monomeric FLT3 ligand variant E Pannecoucke, L Raes, SN Savvides Acta Crystallographica Section F: Structural Biology Communications 77 (4 …, 2021 | 2 | 2021 |
Phase II Trial Assessing the Repeatability and Tumor Uptake of [68Ga] Ga-HER2 Single-Domain Antibody PET/CT in Patients with Breast Carcinoma O Gondry, V Caveliers, C Xavier, L Raes, M Vanhoeij, G Verfaillie, ... Journal of Nuclear Medicine 65 (2), 178-184, 2024 | 1 | 2024 |
VNB-mediated endosomal escape triggers robust gene silencing in human cell lines JC Fraire, G Houthaeve, J Liu, L Raes, S Stremersch, T Brans, ... Colloidal Nanoparticles for Biomedical Applications XV 11255, 1125504, 2020 | 1 | 2020 |
Towards safe and efficient delivery of mRNA and CRISPR-Cas9 complexes in T cells by vapor nanobubble photoporation L Raes, S Stremersch, J Fraire, T Brans, G Goetgeluk, J Van Hoeck, ... HUMAN GENE THERAPY 30 (12), A13-A13, 2019 | 1 | 2019 |
Nanobody-based fluorescent contrast agents for rapid and specific intra-operative tumor visualization S Hernot Molecular-Guided Surgery: Molecules, Devices, and Applications X, PC128250N, 2024 | | 2024 |
First in vivo results for a novel macroscale time-domain fluorescence imaging system H Ingelberts, S Janssen, T Van Den Dries, T Lapauw, S Sahakian, ... | | 2023 |
A comparison of [68Ga] Ga-NOTA-anti-HER2-sdAb PET/CT with [18F] FDG-PET/CT in breast carcinoma patients. O Gondry, C Xavier, J Heemskerk, LAJ Raes, J Debacker, F De Geeter, ... 18th Annual Meeting of the European Molecular Imaging (EMIM 2023), 2023 | | 2023 |
Repeatability of 68GaNOTA-anti-HER2 sdAb in 20 breast cancer patients. O Gondry, C Xavier, F De Geeter, K Glorieus, S Aspeslagh, S Joris, ... EMIM 2022: 17th European Molecular Imaging Meeting, 2022 | | 2022 |