Chemo-and regioselective lysine modification on native proteins MJ Matos, BL Oliveira, N Martínez-Sáez, A Guerreiro, PMSD Cal, ... Journal of the American Chemical Society 140 (11), 4004-4017, 2018 | 273 | 2018 |
Solution structures of chemoenzymatically synthesized heparin and its precursors Z Zhang, SA McCallum, J Xie, L Nieto, F Corzana, J Jiménez-Barbero, ... Journal of the American Chemical Society 130 (39), 12998-13007, 2008 | 214 | 2008 |
Stoichiometric and irreversible cysteine-selective protein modification using carbonylacrylic reagents B Bernardim, PMSD Cal, MJ Matos, BL Oliveira, N Martínez-Sáez, ... Nature Communications 7 (1), 13128, 2016 | 172 | 2016 |
Serine versus threonine glycosylation: the methyl group causes a drastic alteration on the carbohydrate orientation and on the surrounding water shell F Corzana, JH Busto, G Jiménez-Osés, M García de Luis, JL Asensio, ... Journal of the American Chemical Society 129 (30), 9458-9467, 2007 | 159 | 2007 |
New insights into α-GalNAc− Ser motif: Influence of hydrogen bonding versus solvent interactions on the preferred conformation F Corzana, JH Busto, G Jiménez-Osés, JL Asensio, J Jiménez-Barbero, ... Journal of the American Chemical Society 128 (45), 14640-14648, 2006 | 103 | 2006 |
Exploring the use of conformationally locked aminoglycosides as a new strategy to overcome bacterial resistance A Bastida, A Hidalgo, JL Chiara, M Torrado, F Corzana, ... Journal of the American Chemical Society 128 (1), 100-116, 2006 | 103 | 2006 |
Chemoselective installation of amine bonds on proteins through aza-Michael ligation AM Freedy, MJ Matos, O Boutureira, F Corzana, A Guerreiro, P Akkapeddi, ... Journal of the American Chemical Society 139 (50), 18365-18375, 2017 | 102 | 2017 |
Principles of mucin structure: implications for the rational design of cancer vaccines derived from MUC1-glycopeptides N Martínez-Sáez, JM Peregrina, F Corzana Chemical Society Reviews 46 (23), 7154-7175, 2017 | 102 | 2017 |
Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation E Lira-Navarrete, M de Las Rivas, I Compañón, MC Pallarés, Y Kong, ... Nature communications 6 (1), 6937, 2015 | 101 | 2015 |
Substrate‐Guided Front‐Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the Polypeptide N‐Acetylgalactosaminyltransferase 2 E Lira‐Navarrete, J Iglesias‐Fernández, WF Zandberg, I Compañón, ... Angewandte Chemie 126 (31), 8345-8349, 2014 | 101 | 2014 |
Deciphering the Non‐Equivalence of Serine and Threonine O‐Glycosylation Points: Implications for Molecular Recognition of the Tn Antigen by an anti‐MUC1 … N Martínez‐Sáez, J Castro‐López, J Valero‐González, D Madariaga, ... Angewandte Chemie International Edition 54 (34), 9830-9834, 2015 | 92 | 2015 |
A hydration study of (1→ 4) and (1→ 6) linked α‐glucans by comparative 10 ns molecular dynamics simulations and 500‐MHz NMR F Corzana, MS Motawia, CH Du Penhoat, S Perez, SM Tschampel, ... Journal of computational chemistry 25 (4), 573-586, 2004 | 86 | 2004 |
Structure-based design of potent tumor-associated antigens: modulation of peptide presentation by single-atom O/S or O/Se substitutions at the glycosidic linkage I Compañón, A Guerreiro, V Mangini, J Castro-López, M Escudero-Casao, ... Journal of the American Chemical Society 141 (9), 4063-4072, 2019 | 76 | 2019 |
Quaternization of Vinyl/Alkynyl Pyridine Enables Ultrafast Cysteine‐Selective Protein Modification and Charge Modulation MJ Matos, CD Navo, T Hakala, X Ferhati, A Guerreiro, D Hartmann, ... Angewandte Chemie International Edition 58 (20), 6640-6644, 2019 | 75 | 2019 |
Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor T Rodrigues, M Werner, J Roth, EHG da Cruz, MC Marques, P Akkapeddi, ... Chemical Science 9 (34), 6899-6903, 2018 | 75 | 2018 |
Role of aromatic rings in the molecular recognition of aminoglycoside antibiotics: implications for drug design T Vacas, F Corzana, G Jimenez-Oses, C Gonzalez, AM Gomez, A Bastida, ... Journal of the American Chemical Society 132 (34), 12074-12090, 2010 | 75 | 2010 |
Molecular basis for fibroblast growth factor 23 O-glycosylation by GalNAc-T3 M de Las Rivas, EJ Paul Daniel, Y Narimatsu, I Compañón, K Kato, ... Nature chemical biology 16 (3), 351-360, 2020 | 70 | 2020 |
Efficient and irreversible antibody–cysteine bioconjugation using carbonylacrylic reagents B Bernardim, MJ Matos, X Ferhati, I Compañón, A Guerreiro, P Akkapeddi, ... Nature Protocols 14 (1), 86-99, 2019 | 70 | 2019 |
Dynamic acetylation of phosphoenolpyruvate carboxykinase toggles enzyme activity between gluconeogenic and anaplerotic reactions P Latorre-Muro, J Baeza, EA Armstrong, R Hurtado-Guerrero, F Corzana, ... Molecular cell 71 (5), 718-732. e9, 2018 | 68 | 2018 |
A proactive role of water molecules in acceptor recognition by protein O-fucosyltransferase 2 J Valero-González, C Leonhard-Melief, E Lira-Navarrete, ... Nature chemical biology 12 (4), 240-246, 2016 | 68 | 2016 |