HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium D Wu, RT Huang, RB Hamanaka, M Krause, MJ Oh, CH Kuo, ... Elife 6, e25217, 2017 | 135 | 2017 |
Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles CH Kuo, L Leon, EJ Chung, RT Huang, TJ Sontag, CA Reardon, GS Getz, ... Journal of Materials Chemistry B 2 (46), 8142-8153, 2014 | 108 | 2014 |
Mechanosensitive PPAP2B regulates endothelial responses to atherorelevant hemodynamic forces C Wu, RT Huang, CH Kuo, S Kumar, CW Kim, YC Lin, YJ Chen, ... Circulation research 117 (4), e41-e53, 2015 | 106 | 2015 |
Fibroblast-enriched endoplasmic reticulum protein TXNDC5 promotes pulmonary fibrosis by augmenting TGFβ signaling through TGFBR1 stabilization TH Lee, CF Yeh, YT Lee, YC Shih, YT Chen, CT Hung, MY You, PC Wu, ... Nature Communications 11 (1), 4254, 2020 | 74 | 2020 |
Genetic variant at coronary artery disease and ischemic stroke locus 1p32. 2 regulates endothelial responses to hemodynamics MD Krause, RT Huang, D Wu, TP Shentu, DL Harrison, MB Whalen, ... Proceedings of the National Academy of Sciences 115 (48), E11349-E11358, 2018 | 68 | 2018 |
Experimental lung injury reduces Krüppel-like factor 2 to increase endothelial permeability via regulation of RAPGEF3–Rac1 signaling RT Huang, D Wu, A Meliton, MJ Oh, M Krause, JA Lloyd, R Nigdelioglu, ... American journal of respiratory and critical care medicine 195 (5), 639-651, 2017 | 54 | 2017 |
Host MicroRNA miR-197 Plays a Negative Regulatory Role in the Enterovirus 71 Infectious Cycle by Targeting the RAN Protein WF Tang, RT Huang, KY Chien, JY Huang, KS Lau, JR Jheng, CH Chiu, ... Journal of Virology 90 (3), 1424-38, 2015 | 49 | 2015 |
Proatherogenic flow increases endothelial stiffness via enhanced CD36-mediated uptake of oxidized low-density lipoproteins E Le Master, RT Huang, C Zhang, Y Bogachkov, C Coles, TP Shentu, ... Arteriosclerosis, thrombosis, and vascular biology 38 (1), 64-75, 2018 | 40 | 2018 |
Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells D Wu, DL Harrison, T Szasz, CF Yeh, TP Shentu, A Meliton, RT Huang, ... Nature metabolism 3 (5), 714-727, 2021 | 36 | 2021 |
Targeted polyelectrolyte complex micelles treat vascular complications in vivo Z Zhou, CF Yeh, M Mellas, MJ Oh, J Zhu, J Li, RT Huang, DL Harrison, ... Proceedings of the National Academy of Sciences 118 (50), e2114842118, 2021 | 22 | 2021 |
Targeting mechanosensitive endothelial TXNDC5 to stabilize eNOS and reduce atherosclerosis in vivo CF Yeh, SH Cheng, YS Lin, TP Shentu, RT Huang, J Zhu, YT Chen, ... Science Advances 8 (3), eabl8096, 2022 | 11 | 2022 |
Proteolytic processing of porcine deoxyribonuclease II occurs in lysosomes but is not required for enzyme activation RT Huang, TH Liao, SC Lu The FEBS Journal 276 (7), 1891-1899, 2009 | 8 | 2009 |
SARS-CoV-2 Infection is associated with reduced Krüppel-like factor 2 in human lung autopsy D Wu, TH Lee, RT Huang, R D. Guzy, N Schoettler, A Adegunsoye, ... American Journal of Respiratory Cell and Molecular Biology 65 (2), 222-226, 2021 | 5 | 2021 |
Large-scale proteomic identification of targets of cellular miR-197 downregulated by enterovirus A71 WF Tang, RT Huang, KY Chien, P Tang, JT Horng Journal of proteome research 18 (1), 449-460, 2018 | 4 | 2018 |
Proatherogenic Flow Increases Endothelial Stiffness via Enhanced CD36 (Cluster of Differentiation 36)-Mediated OxLDL (Oxidized Low-Density Lipoprotein) Uptake E Le Master, RT Huang, C Zhang, Y Bogachkov, C Coles, TP Shentu, ... Arteriosclerosis, Thrombosis and Vascular Biology, 2017 | 4 | 2017 |
Targeting dys‐regulated mechano‐transduction mechanisms in treating arterial and pulmonary vascular diseases by nanomedicine Y Fang, RT Huang, D Wu, MJ Oh, L Leon, G Mutlu, M Tirrell The FASEB Journal 31, 1015.13-1015.13, 2017 | 2 | 2017 |
Coronary Artery Disease Risk Variant Dampens the Expression of CALCRL by Reducing HSF Binding to Shear Stress Responsive Enhancer in Endothelial Cells In Vitro I Selvarajan, M Kiema, RT Huang, J Li, J Zhu, P Pölönen, T Örd, K Õunap, ... Arteriosclerosis, Thrombosis, and Vascular Biology, 2024 | 1 | 2024 |
Endothelial restoration of CAD GWAS gene PLPP3 by nanomedicine suppresses YAP/TAZ activity and reduces atherosclerosis in vivo J Zhu, CF Yeh, RT Huang, TH Lee, TP Shentu, D Wu, KC Yang, Y Fang bioRxiv, 2021.05. 06.443006, 2021 | 1 | 2021 |
HIF-1α Is Required For Flow-Mediated Regulation Of Endothelial Cell Metabolism D Wu, RT Huang, M Krause, R Hamanaka, LJ Witt, R Nigdelioglu, ... C107. MITOCHONDRIA AND METABOLIC ALTERATIONS IN LUNG DISEASE, A6910-A6910, 2017 | 1 | 2017 |
Klf2 enhances barrier protection by directly regulating Rapgef3, a Gef which activates Rac1 DD Wu, RT Huang, M Jain, AA Birukova, J Lloyd, GM Mutlu, KG Birukov, ... C67. ACUTE LUNG INJURY, A5754-A5754, 2016 | 1 | 2016 |