Follow
Daniel G. Isom
Daniel G. Isom
University of Miami School of Medicine
Verified email at miami.edu - Homepage
Title
Cited by
Cited by
Year
Large shifts in pKa values of lysine residues buried inside a protein
DG Isom, CA Castañeda, BR Cannon, B García-Moreno E
Proceedings of the National Academy of Sciences 108 (13), 5260-5265, 2011
4232011
Charges in the hydrophobic interior of proteins
DG Isom, CA Castañeda, BR Cannon, PD Velu, B García-Moreno E
Proceedings of the National Academy of Sciences 107 (37), 16096-16100, 2010
2322010
High tolerance for ionizable residues in the hydrophobic interior of proteins
DG Isom, BR Cannon, CA Castañeda, A Robinson, B García-Moreno E
Proceedings of the National Academy of Sciences 105 (46), 17784-17788, 2008
1602008
Local secondary structure content predicts folding rates for simple, two-state proteins
H Gong, DG Isom, R Srinivasan, GD Rose
Journal of molecular biology 327 (5), 1149-1154, 2003
1422003
The pKa values of acidic and basic residues buried at the same internal location in a protein are governed by different factors
MJ Harms, CA Castañeda, JL Schlessman, GR Sue, DG Isom, ...
Journal of molecular biology 389 (1), 34-47, 2009
1332009
One year of SARS-CoV-2: how much has the virus changed?
S Vilar, DG Isom
Biology 10 (2), 91, 2021
962021
Protons as second messenger regulators of G protein signaling
DG Isom, V Sridharan, R Baker, ST Clement, DM Smalley, HG Dohlman
Molecular Cell 51 (4), 531-538, 2013
682013
Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination
R Baker, EM Wilkerson, K Sumita, DG Isom, AT Sasaki, HG Dohlman, ...
Journal of Biological Chemistry 288 (52), 36856-36862, 2013
662013
Hydration of the folding transition state ensemble of a protein
L Brun, DG Isom, P Velu, B García-Moreno, CA Royer
Biochemistry 45 (11), 3473-3480, 2006
562006
Mutations in ATP1A1 cause dominant Charcot-Marie-Tooth type 2
P Lassuthova, AP Rebelo, G Ravenscroft, PJ Lamont, MR Davis, ...
The American Journal of Human Genetics 102 (3), 505-514, 2018
552018
Buried ionizable networks are an ancient hallmark of G protein-coupled receptor activation
DG Isom, HG Dohlman
Proceedings of the National Academy of Sciences 112 (18), 5702-5707, 2015
392015
V i-value analysis: a pressure-based method for mapping the folding transition state ensemble of proteins
L Mitra, K Hata, R Kono, A Maeno, D Isom, JB Rouget, R Winter, ...
Journal of the American Chemical Society 129 (46), 14108-14109, 2007
392007
Picomole-scale characterization of protein stability and function by quantitative cysteine reactivity
DG Isom, E Vardy, TG Oas, HW Hellinga
Proceedings of the National Academy of Sciences 107 (11), 4908-4913, 2010
352010
A miniaturized technique for assessing protein thermodynamics and function using fast determination of quantitative cysteine reactivity
DG Isom, PR Marguet, TG Oas, HW Hellinga
Proteins: Structure, Function, and Bioinformatics 79 (4), 1034-1047, 2011
312011
DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery
NJ Kapolka, GJ Taghon, JB Rowe, WM Morgan, JF Enten, NA Lambert, ...
Proceedings of the National Academy of Sciences 117 (23), 13117-13126, 2020
282020
Predictable cholesterol binding sites in GPCRs lack consensus motifs
GJ Taghon, JB Rowe, NJ Kapolka, DG Isom
Structure 29 (5), 499-506. e3, 2021
272021
Coordinated regulation of intracellular pH by two glucose-sensing pathways in yeast
DG Isom, SC Page, LB Collins, NJ Kapolka, GJ Taghon, HG Dohlman
Journal of Biological Chemistry 293 (7), 2318-2329, 2018
212018
Amino acid metabolites that regulate G protein signaling during osmotic stress
JP Shellhammer, E Morin-Kensicki, JP Matson, G Yin, DG Isom, ...
PLoS genetics 13 (5), e1006829, 2017
182017
The evolution and mechanism of GPCR proton sensing
JB Rowe, NJ Kapolka, GJ Taghon, WM Morgan, DG Isom
Journal of Biological Chemistry 296, 2021
172021
Regulation of Ras paralog thermostability by networks of buried ionizable groups
DG Isom, V Sridharan, HG Dohlman
Biochemistry 55 (3), 534-542, 2016
112016
The system can't perform the operation now. Try again later.
Articles 1–20