Tamer S  Kaoud
Tamer S Kaoud
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Targeted silencing of elongation factor 2 kinase suppresses growth and sensitizes tumors to doxorubicin in an orthotopic model of breast cancer
I Tekedereli, SN Alpay, CDJ Tavares, ZE Cobanoglu, TS Kaoud, I Sahin, ...
PloS one 7 (7), e41171, 2012
193‐nm photodissociation of singly and multiply charged peptide anions for acidic proteome characterization
JA Madsen, TS Kaoud, KN Dalby, JS Brodbelt
Proteomics 11 (7), 1329-1334, 2011
c-Jun N-terminal kinase promotes stem cell phenotype in triple-negative breast cancer through upregulation of Notch1 via activation of c-Jun
X Xie, TS Kaoud, R Edupuganti, T Zhang, T Kogawa, Y Zhao, ...
Oncogene 36 (18), 2599-2608, 2017
Calcium/calmodulin stimulates the autophosphorylation of elongation factor 2 kinase on Thr-348 and Ser-500 to regulate its activity and calcium dependence
CDJ Tavares, JP O’Brien, O Abramczyk, AK Devkota, KS Shores, ...
Biochemistry 51 (11), 2232-2245, 2012
Investigating the kinetic mechanism of inhibition of elongation factor 2 kinase by NH125: evidence of a common in vitro artifact
AK Devkota, CDJ Tavares, M Warthaka, O Abramczyk, KD Marshall, ...
Biochemistry 51 (10), 2100-2112, 2012
In-situ generation of differential sensors that fingerprint kinases and the cellular response to their expression
D Zamora-Olivares, TS Kaoud, KN Dalby, EV Anslyn
Journal of the American Chemical Society 135 (39), 14814-14820, 2013
Nonvisual arrestins function as simple scaffolds assembling the MKK4–JNK3α2 signaling complex
X Zhan, TS Kaoud, KN Dalby, VV Gurevich
Biochemistry 50 (48), 10520-10529, 2011
Arrestin-3 binds c-Jun N-terminal kinase 1 (JNK1) and JNK2 and facilitates the activation of these ubiquitous JNK isoforms in cells via scaffolding
S Kook, X Zhan, TS Kaoud, KN Dalby, VV Gurevich, EV Gurevich
Journal of Biological Chemistry 288 (52), 37332-37342, 2013
JNK3 enzyme binding to arrestin-3 differentially affects the recruitment of upstream mitogen-activated protein (MAP) kinase kinases
X Zhan, TS Kaoud, S Kook, KN Dalby, VV Gurevich
Journal of Biological Chemistry 288 (40), 28535-28547, 2013
Peptide mini-scaffold facilitates JNK3 activation in cells
X Zhan, H Stoy, TS Kaoud, NA Perry, Q Chen, A Perez, S Els-Heindl, ...
Scientific Reports 6 (1), 21025, 2016
Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration
TS Kaoud, S Mitra, S Lee, J Taliaferro, M Cantrell, KD Linse, ...
ACS chemical biology 6 (6), 658-666, 2011
Novel 1-[4-(Aminosulfonyl) phenyl]-1H-1, 2, 4-triazole derivatives with remarkable selective COX-2 inhibition: Design, synthesis, molecular docking, anti-inflammatory and …
GEDAA Abuo-Rahma, M Abdel-Aziz, NA Farag, TS Kaoud
European journal of medicinal chemistry 83, 398-408, 2014
New 1, 3, 4-oxadiazole/oxime hybrids: Design, synthesis, anti-inflammatory, COX inhibitory activities and ulcerogenic liability
HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ...
Bioorganic Chemistry 74, 15-29, 2017
Activated ERK2 is a monomer in vitro with or without divalent cations and when complexed to the cytoplasmic scaffold PEA-15
TS Kaoud, AK Devkota, R Harris, MS Rana, O Abramczyk, M Warthaka, ...
Biochemistry 50 (21), 4568-4578, 2011
Novel quinoline incorporating 1, 2, 4-triazole/oxime hybrids: synthesis, molecular docking, anti-inflammatory, COX inhibition, ulceroginicity and histopathological investigations
AM Mohassab, HA Hassan, D Abdelhamid, M Abdel-Aziz, KN Dalby, ...
Bioorganic chemistry 75, 242-259, 2017
Differential sensing of MAP kinases using SOX‐peptides
D Zamora‐Olivares, TS Kaoud, J Jose, A Ellington, KN Dalby, EV Anslyn
Angewandte Chemie International Edition 53 (51), 14064-14068, 2014
Solution NMR insights into docking interactions involving inactive ERK2
A Piserchio, M Warthaka, AK Devkota, TS Kaoud, S Lee, O Abramczyk, ...
Biochemistry 50 (18), 3660-3672, 2011
Novel 1, 3, 4-oxadiazole/oxime hybrids: Synthesis, docking studies and investigation of anti-inflammatory, ulcerogenic liability and analgesic activities
HS Abd-Ellah, M Abdel-Aziz, ME Shoman, EAM Beshr, TS Kaoud, ...
Bioorganic chemistry 69, 48-63, 2016
Examining docking interactions on ERK2 with modular peptide substrates
S Lee, M Warthaka, C Yan, TS Kaoud, P Ren, KN Dalby
Biochemistry 50 (44), 9500-9510, 2011
Pro-metastatic collagen lysyl hydroxylase dimer assemblies stabilized by Fe2+-binding
HF Guo, CL Tsai, M Terajima, X Tan, P Banerjee, MD Miller, X Liu, J Yu, ...
Nature communications 9 (1), 512, 2018
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