| Iterative approach to computational enzyme design HK Privett, G Kiss, TM Lee, R Blomberg, RA Chica, LM Thomas, D Hilvert, ... Proceedings of the National Academy of Sciences 109 (10), 3790-3795, 2012 | 378 | 2012 |
| Precision is essential for efficient catalysis in an evolved Kemp eliminase R Blomberg, H Kries, DM Pinkas, PRE Mittl, MG Grütter, HK Privett, ... Nature 503 (7476), 418-421, 2013 | 347 | 2013 |
| De novo enzymes by computational design H Kries, R Blomberg, D Hilvert Current opinion in chemical biology 17 (2), 221-228, 2013 | 292 | 2013 |
| Computational design of catalytic dyads and oxyanion holes for ester hydrolysis F Richter, R Blomberg, SD Khare, G Kiss, AP Kuzin, AJT Smith, J Gallaher, ... Journal of the American Chemical Society 134 (39), 16197-16206, 2012 | 186 | 2012 |
| Evolved aliphatic halogenases enable regiocomplementary C− H functionalization of a pharmaceutically relevant compound T Hayashi, M Ligibel, E Sager, M Voss, J Hunziker, K Schroer, ... Angewandte Chemie International Edition 58 (51), 18535-18539, 2019 | 65 | 2019 |
| Design of a highly specific and noninvasive biosensor suitable for real‐time in vivo imaging of mercury (II) uptake RR Chapleau, R Blomberg, PC Ford, M Sagermann Protein Science 17 (4), 614-622, 2008 | 51 | 2008 |
| From nature to industry: Harnessing enzymes for biocatalysis R Buller, S Lutz, RJ Kazlauskas, R Snajdrova, JC Moore, UT Bornscheuer Science 382 (6673), eadh8615, 2023 | 48 | 2023 |
| Algorithm-aided engineering of aliphatic halogenase WelO5* for the asymmetric late-stage functionalization of soraphens J Büchler, SH Malca, D Patsch, M Voss, NJ Turner, UT Bornscheuer, ... Nature Communications 13 (1), 371, 2022 | 47 | 2022 |
| Exploring the biocatalytic potential of Fe/α‐ketoglutarate‐dependent halogenases M Voss, S Honda Malca, R Buller Chemistry–A European Journal 26 (33), 7336-7345, 2020 | 45 | 2020 |
| Industrial application of 2-oxoglutarate-dependent oxygenases C Peters, RM Buller Catalysts 9 (3), 221, 2019 | 45 | 2019 |
| Recent advances in flavin-dependent halogenase biocatalysis: sourcing, engineering, and application J Büchler, A Papadopoulou, R Buller Catalysts 9 (12), 1030, 2019 | 41 | 2019 |
| Enzymatic PET degradation A Papadopoulou, K Hecht, R Buller Chimia 73 (9), 743-743, 2019 | 40 | 2019 |
| Novel old yellow enzyme subclasses C Peters, D Frasson, M Sievers, R Buller ChemBioChem 20 (12), 1569-1577, 2019 | 35 | 2019 |
| Directed evolution of carbon–hydrogen bond activating enzymes R Frey, T Hayashi, RM Buller Current opinion in biotechnology 60, 29-38, 2019 | 31 | 2019 |
| Re‐Programming and Optimization of a L‐Proline cis‐4‐Hydroxylase for the cis‐3‐Halogenation of its Native Substrate A Papadopoulou, J Meierhofer, F Meyer, T Hayashi, S Schneider, E Sager, ... ChemCatChem 13 (18), 3914-3919, 2021 | 30 | 2021 |
| Modulating chemoselectivity in a Fe (II)/α-ketoglutarate-dependent dioxygenase for the oxidative modification of a nonproteinogenic amino acid F Meyer, R Frey, M Ligibel, E Sager, K Schroer, R Snajdrova, R Buller ACS Catalysis 11 (10), 6261-6269, 2021 | 23 | 2021 |
| Engineering Fe (II)/α-ketoglutarate-dependent halogenases and desaturases A Papadopoulou, F Meyer, RM Buller Biochemistry 62 (2), 229-240, 2022 | 22 | 2022 |
| Asymmetric cation‐olefin monocyclization by engineered squalene–hopene cyclases M Eichenberger, S Hüppi, D Patsch, N Aeberli, R Berweger, ... Angewandte Chemie International Edition 60 (50), 26080-26086, 2021 | 20 | 2021 |
| Biocatalysis in the swiss manufacturing environment K Hecht, HP Meyer, R Wohlgemuth, R Buller Catalysts 10 (12), 1420, 2020 | 16 | 2020 |
| Multi‐faceted set‐up of a diverse ketoreductase library enables the synthesis of pharmaceutically‐relevant secondary alcohols M Voss, R Küng, T Hayashi, M Jonczyk, M Niklaus, H Iding, D Wetzl, ... ChemCatChem 13 (6), 1538-1545, 2021 | 15 | 2021 |
