| Neighboring group participation in Lewis acid-promoted [3+ 4] and [3+ 5] annulations. The synthesis of oxabicyclo [3. n. 1] alkan-3-ones GA Molander, KO Cameron Journal of the American Chemical Society 115 (3), 830-846, 1993 | 264 | 1993 |
| Activation of skeletal muscle AMPK promotes glucose disposal and glucose lowering in non-human primates and mice EC Cokorinos, J Delmore, AR Reyes, B Albuquerque, R Kjøbsted, ... Cell metabolism 25 (5), 1147-1159. e10, 2017 | 245 | 2017 |
| An EP2 receptor-selective prostaglandin E2 agonist induces bone healing VM Paralkar, F Borovecki, HZ Ke, KO Cameron, B Lefker, WA Grasser, ... Proceedings of the National Academy of Sciences 100 (11), 6736-6740, 2003 | 240 | 2003 |
| Effects of CP-336,156, a new, nonsteroidal estrogen agonist/antagonist, on bone, serum cholesterol, uterus, and body composition in rat models HZ Ke, VM Paralkar, WA Grasser, DT Crawford, H Qi, HA Simmons, ... Endocrinology 139 (4), 2068-2076, 1998 | 210 | 1998 |
| Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms MF Calabrese, F Rajamohan, MS Harris, NL Caspers, R Magyar, ... Structure 22 (8), 1161-1172, 2014 | 179 | 2014 |
| A Novel, Non‐Prostanoid EP2 Receptor‐Selective Prostaglandin E2 Agonist Stimulates Local Bone Formation and Enhances Fracture Healing M Li, HZ Ke, H Qi, DR Healy, Y Li, DT Crawford, VM Paralkar, TA Owen, ... Journal of Bone and Mineral Research 18 (11), 2033-2042, 2003 | 154 | 2003 |
| Discovery and preclinical pharmacology of a novel, potent, nonsteroidal estrogen receptor agonist/antagonist, CP-336156, a diaryltetrahydronaphthalene RL Rosati, P Da Silva Jardine, KO Cameron, DD Thompson, HZ Ke, ... Journal of medicinal chemistry 41 (16), 2928-2931, 1998 | 147 | 1998 |
| 5-substitued-6-cyclic-5, 6, 7, 8-tetrahydronaphthalen2-ol compounds which are useful for treating osteoporosis KO Cameron, PAD Jardine, RL Rosati US Patent 5,552,412, 1996 | 133 | 1996 |
| Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of … KO Cameron, DW Kung, AS Kalgutkar, RG Kurumbail, R Miller, CT Salatto, ... Journal of medicinal chemistry 59 (17), 8068-8081, 2016 | 120 | 2016 |
| Activation of liver AMPK with PF-06409577 corrects NAFLD and lowers cholesterol in rodent and primate preclinical models RM Esquejo, CT Salatto, J Delmore, B Albuquerque, A Reyes, Y Shi, ... EBioMedicine 31, 122-132, 2018 | 114 | 2018 |
| Selective activation of AMPK β1-containing isoforms improves kidney function in a rat model of diabetic nephropathy CT Salatto, RA Miller, KO Cameron, E Cokorinos, A Reyes, J Ward, ... Journal of Pharmacology and Experimental Therapeutics 361 (2), 303-311, 2017 | 78 | 2017 |
| Intestinal targeting of drugs: rational design approaches and challenges KJ Filipski, MV Varma, AF El-Kattan, CM Ambler, RB Ruggeri, TC Goosen, ... Current Topics in Medicinal Chemistry 13 (7), 776-802, 2013 | 74 | 2013 |
| A Nonprostanoid EP4 Receptor Selective Prostaglandin E2 Agonist Restores Bone Mass and Strength in Aged, Ovariectomized Rats HZ Ke, DT Crawford, H Qi, HA Simmons, TA Owen, VM Paralkar, M Li, ... Journal of Bone and Mineral Research 21 (4), 565-575, 2006 | 71 | 2006 |
| Neighboring group participation in Lewis acid-promoted [3+ 4] and [3+ 5] annulations. The stereocontrolled synthesis of tricyclic ethers GA Molander, KO Cameron The Journal of Organic Chemistry 58 (22), 5931-5943, 1993 | 70 | 1993 |
| Tetraazabenzo [e] azulene derivatives and analogs thereof RL Elliott, KO Cameron, M Hammond US Patent 7,265,104, 2007 | 64 | 2007 |
| Discovery of PF-5190457, a potent, selective, and orally bioavailable ghrelin receptor inverse agonist clinical candidate SK Bhattacharya, K Andrews, R Beveridge, KO Cameron, C Chen, ... ACS medicinal chemistry letters 5 (5), 474-479, 2014 | 62 | 2014 |
| A novel concept for regiochemical and stereochemical control in Lewis acid promoted [3+ 4] annulation reactions GA Molander, KO Cameron The Journal of Organic Chemistry 56 (8), 2617-2619, 1991 | 56 | 1991 |
| Medicinal chemistry design principles for liver targeting through OATP transporters M Tu, AM Mathiowetz, JA Pfefferkorn, KO Cameron, RL Dow, J Litchfield, ... Current Topics in Medicinal Chemistry 13 (7), 857-866, 2013 | 54 | 2013 |
| Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators KO Cameron, RG Kurumbail Bioorganic & Medicinal Chemistry Letters 26 (21), 5139-5148, 2016 | 49 | 2016 |
| Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats KO Cameron, BA Lefker, MY Chu-Moyer, DT Crawford, PDS Jardine, ... Bioorganic & medicinal chemistry letters 16 (7), 1799-1802, 2006 | 46 | 2006 |
