Aging in inbred strains of mice: study design and interim report on median lifespans and circulating IGF1 levels R Yuan, SW Tsaih, SB Petkova, CM De Evsikova, S Xing, MA Marion, ... Aging cell 8 (3), 277-287, 2009 | 439 | 2009 |
The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals JM Murabito, R Yuan, KL Lunetta Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2012 | 211 | 2012 |
Mice as a mammalian model for research on the genetics of aging R Yuan, LL Peters, B Paigen ILAR journal 52 (1), 4-15, 2011 | 143 | 2011 |
Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains R Yuan, Q Meng, J Nautiyal, K Flurkey, SW Tsaih, R Krier, MG Parker, ... Proceedings of the National Academy of Sciences 109 (21), 8224-8229, 2012 | 106 | 2012 |
Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans BP Lee, LC Pilling, F Emond, K Flurkey, DE Harrison, R Yuan, LL Peters, ... Aging cell 15 (5), 903-913, 2016 | 92 | 2016 |
The mouse as a model for understanding chronic diseases of aging: the histopathologic basis of aging in inbred mice JP Sundberg, A Berndt, BA Sundberg, KA Silva, V Kennedy, R Bronson, ... Pathobiology of Aging & Age-related Diseases 1 (1), 7179, 2011 | 90 | 2011 |
Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages SB Petkova, R Yuan, SW Tsaih, W Schott, DC Roopenian, B Paigen Physiological genomics 34 (3), 304-314, 2008 | 84 | 2008 |
Metabolic syndrome and skin diseases Y Hu, Y Zhu, N Lian, M Chen, A Bartke, R Yuan Frontiers in endocrinology 10, 788, 2019 | 74 | 2019 |
Genetic influence on electrocardiogram time intervals and heart rate in aging mice S Xing, SW Tsaih, R Yuan, KL Svenson, LM Jorgenson, M So, BJ Paigen, ... American Journal of Physiology-Heart and Circulatory Physiology 296 (6 …, 2009 | 59 | 2009 |
Molecular mechanisms of irradiation-induced apoptosis L Zhou, R Yuan, S Lanata Frontiers in bioscience: a journal and virtual library 8, d9, 2003 | 57 | 2003 |
Genetic regulation of hematopoietic stem cell exhaustion during development and growth R Yuan, CM Astle, J Chen, DE Harrison Experimental hematology 33 (2), 243-250, 2005 | 54 | 2005 |
Genetic analysis of albuminuria in aging mice and concordance with loci for human diabetic nephropathy found in a genome-wide association scan SW Tsaih, MG Pezzolesi, R Yuan, JH Warram, AS Krolewski, R Korstanje Kidney international 77 (3), 201-210, 2010 | 48 | 2010 |
Accessing data resources in the mouse phenome database for genetic analysis of murine life span and health span MA Bogue, LL Peters, B Paigen, R Korstanje, R Yuan, C Ackert-Bicknell, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2016 | 44 | 2016 |
Effects of rapamycin on growth hormone receptor knockout mice Y Fang, CM Hill, J Darcy, A Reyes-Ordoñez, E Arauz, S McFadden, ... Proceedings of the National Academy of Sciences 115 (7), E1495-E1503, 2018 | 43 | 2018 |
Suppressing NRIP1 inhibits growth of breast cancer cells in vitro and in vivo MH Aziz, X Chen, Q Zhang, C DeFrain, J Osland, Y Luo, X Shi, R Yuan Oncotarget 6 (37), 39714, 2015 | 42 | 2015 |
Genetic analysis of mouse strains with variable serum sodium concentrations identifies the Nalcn sodium channel as a novel player in osmoregulation AP Sinke, C Caputo, SW Tsaih, R Yuan, D Ren, PMT Deen, R Korstanje Physiological genomics 43 (5), 265-270, 2011 | 40 | 2011 |
Potentiation of psoriasis-like inflammation by PCSK9 C Luan, X Chen, Y Zhu, JM Osland, SD Gerber, M Dodds, Y Hu, M Chen, ... Journal of Investigative Dermatology 139 (4), 859-867, 2019 | 39 | 2019 |
PohnB6F1: a cross of wild and domestic mice that is a new model of extended female reproductive life span K Flurkey, Y Brandvain, S Klebanov, SN Austad, RA Miller, R Yuan, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2007 | 38 | 2007 |
Identification of genetic determinants of IGF‐1 levels and longevity among mouse inbred strains MS Leduc, RS Hageman, Q Meng, RA Verdugo, SW Tsaih, GA Churchill, ... Aging cell 9 (5), 823-836, 2010 | 35 | 2010 |
Hammerhead ribozyme targeting connective tissue growth factor mRNA blocks transforming growth factor-beta mediated cell proliferation TD Blalock, R Yuan, AS Lewin, GS Schultz Experimental eye research 78 (6), 1127-1136, 2004 | 33 | 2004 |