Martin Enge
TitleCited byYear
Small molecule RITA binds to p53, blocks p53–HDM-2 interaction and activates p53 function in tumors
N Issaeva, P Bozko, M Enge, M Protopopova, LGGC Verhoef, M Masucci, ...
Nature medicine 10 (12), 1321, 2004
7662004
DNA-binding specificities of human transcription factors
A Jolma, J Yan, T Whitington, J Toivonen, KR Nitta, P Rastas, ...
Cell 152 (1-2), 327-339, 2013
7142013
Counting absolute numbers of molecules using unique molecular identifiers
T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ...
Nature methods 9 (1), 72, 2012
5482012
Genome‐wide analysis of ETS‐family DNA‐binding in vitro and in vivo
GH Wei, G Badis, MF Berger, T Kivioja, K Palin, M Enge, M Bonke, ...
The EMBO journal 29 (13), 2147-2160, 2010
4702010
A survey of human brain transcriptome diversity at the single cell level
S Darmanis, SA Sloan, Y Zhang, M Enge, C Caneda, LM Shuer, ...
Proceedings of the National Academy of Sciences 112 (23), 7285-7290, 2015
4382015
MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas
N Mäkinen, M Mehine, J Tolvanen, E Kaasinen, Y Li, HJ Lehtonen, ...
Science 334 (6053), 252-255, 2011
4272011
Multiplexed massively parallel SELEX for characterization of human transcription factor binding specificities
A Jolma, T Kivioja, J Toivonen, L Cheng, G Wei, M Enge, M Taipale, ...
Genome research 20 (6), 861-873, 2010
3322010
Transcription factor binding in human cells occurs in dense clusters formed around cohesin anchor sites
J Yan, M Enge, T Whitington, K Dave, J Liu, I Sur, B Schmierer, A Jolma, ...
Cell 154 (4), 801-813, 2013
2202013
DNA-dependent formation of transcription factor pairs alters their binding specificity
A Jolma, Y Yin, KR Nitta, K Dave, A Popov, M Taipale, M Enge, T Kivioja, ...
Nature 527 (7578), 384, 2015
2192015
CTCF/cohesin-binding sites are frequently mutated in cancer
R Katainen, K Dave, E Pitkänen, K Palin, T Kivioja, N Välimäki, AE Gylfe, ...
Nature genetics 47 (7), 818, 2015
2052015
Mice lacking a Myc enhancer that includes human SNP rs6983267 are resistant to intestinal tumors
IK Sur, O Hallikas, A Vähärautio, J Yan, M Turunen, M Enge, M Taipale, ...
Science 338 (6112), 1360-1363, 2012
1742012
MDM2-dependent downregulation of p21 and hnRNP K provides a switch between apoptosis and growth arrest induced by pharmacologically activated p53
M Enge, W Bao, E Hedström, SP Jackson, A Moumen, G Selivanova
Cancer cell 15 (3), 171-183, 2009
1482009
Capture Hi-C identifies the chromatin interactome of colorectal cancer risk loci
R Jäger, G Migliorini, M Henrion, R Kandaswamy, HE Speedy, A Heindl, ...
Nature communications 6, 6178, 2015
1242015
Ablation of key oncogenic pathways by RITA-reactivated p53 is required for efficient apoptosis
VV Grinkevich, F Nikulenkov, Y Shi, M Enge, W Bao, A Maljukova, ...
Cancer cell 15 (5), 441-453, 2009
1062009
Single-cell analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns
M Enge, HE Arda, M Mignardi, J Beausang, R Bottino, SK Kim, SR Quake
Cell 171 (2), 321-330. e14, 2017
842017
Inhibition of glycolytic enzymes mediated by pharmacologically activated p53 targeting Warburg effect to fight cancer
J Zawacka-Pankau, VV Grinkevich, S Hünten, F Nikulenkov, A Gluch, H Li, ...
Journal of Biological Chemistry 286 (48), 41600-41615, 2011
812011
Pharmacological activation of p53 triggers anticancer innate immune response through induction of ULBP2
H Li, T Lakshmikanth, C Garofalo, M Enge, C Spinnler, A Anichini, ...
Cell cycle 10 (19), 3346-3358, 2011
712011
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx
H Chakravarthy, X Gu, M Enge, X Dai, Y Wang, N Damond, C Downie, ...
Cell metabolism 25 (3), 622-634, 2017
442017
Tumor-specific induction of apoptosis by a p53-reactivating compound
E Hedström, N Issaeva, M Enge, G Selivanova
Experimental cell research 315 (3), 451-461, 2009
222009
Protein kinase Cα (PKCα) regulates p53 localization and melanoma cell survival downstream of integrin αv in three-dimensional collagen and in vivo
SD Smith, M Enge, W Bao, M Thullberg, TDF Costa, H Olofsson, B Gashi, ...
Journal of Biological Chemistry 287 (35), 29336-29347, 2012
122012
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Articles 1–20