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Karim Echtay
Karim Echtay
Professor of Biochemistry
Bestätigte E-Mail-Adresse bei balamand.edu.lb
Titel
Zitiert von
Zitiert von
Jahr
Superoxide activates mitochondrial uncoupling proteins
KS Echtay, D Roussel, J St-Pierre, MB Jekabsons, S Cadenas, JA Stuart, ...
Nature 415 (6867), 96-99, 2002
16652002
A signalling role for 4‐hydroxy‐2‐nonenal in regulation of mitochondrial uncoupling
KS Echtay, TC Esteves, JL Pakay, MB Jekabsons, AJ Lambert, ...
The EMBO journal, 2003
7082003
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side: studies using targeted antioxidants
KS Echtay, MP Murphy, RAJ Smith, DA Talbot, MD Brand
Journal of Biological Chemistry 277 (49), 47129-47135, 2002
5102002
Mitochondrial uncoupling proteins—what is their physiological role?
KS Echtay
Free Radical Biology and Medicine 43 (10), 1351-1371, 2007
4502007
Coenzyme Q is an obligatory cofactor for uncoupling protein function
KS Echtay, E Winkler, M Klingenberg
Nature 408 (6812), 609-613, 2000
4232000
Uncoupling proteins 2 and 3 are highly active H+ transporters and highly nucleotide sensitive when activated by coenzyme Q (ubiquinone)
KS Echtay, E Winkler, K Frischmuth, M Klingenberg
Proceedings of the National Academy of Sciences 98 (4), 1416-1421, 2001
4132001
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from …
MP Murphy, KS Echtay, FH Blaikie, J Asin-Cayuela, HM Cochemé, ...
Journal of Biological Chemistry 278 (49), 48534-48545, 2003
3712003
Uncoupling proteins: the issues from a biochemist point of view
M Klingenberg, KS Echtay
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1504 (1), 128-143, 2001
2382001
The basal proton conductance of skeletal muscle mitochondria from transgenic mice overexpressing or lacking uncoupling protein-3
S Cadenas, KS Echtay, JA Harper, MB Jekabsons, JA Buckingham, ...
Journal of Biological Chemistry 277 (4), 2773-2778, 2002
2342002
Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production
MD Brand, JA Buckingham, TC Esteves, K Green, AJ Lambert, S Miwa, ...
Biochemical Society Symposia 71, 203-213, 2004
2322004
Superoxide stimulates a proton leak in potato mitochondria that is related to the activity of uncoupling protein
MJ Considine, M Goodman, KS Echtay, M Laloi, J Whelan, MD Brand, ...
Journal of Biological Chemistry 278 (25), 22298-22302, 2003
1612003
H+ transport by uncoupling protein (UCP-1) is dependent on a histidine pair, absent in UCP-2 and UCP-3
M Bienengraeber, KS Echtay, M Klingenberg
Biochemistry 37 (1), 3-8, 1998
1281998
Site-directed mutagenesis identifies residues in uncoupling protein (UCP1) involved in three different functions
KS Echtay, E Winkler, M Bienengraeber, M Klingenberg
Biochemistry 39 (12), 3311-3317, 2000
892000
Structure–function relationship in UCP1
M Klingenberg, KS Echtay, M Bienengraeber, E Winkler, SG Huang
International Journal of Obesity 23 (6), S24-S29, 1999
851999
4-hydroxy-2-nonenal and uncoupling proteins: an approach for regulation of mitochondrial ROS production
KS Echtay, MD Brand
Redox Report 12 (1-2), 26-29, 2007
812007
Hydroxynonenal and uncoupling proteins: a model for protection against oxidative damage
KS Echtay, JL Pakay, TC Esteves, MD Brand
Biofactors 24 (1‐4), 119-130, 2005
792005
Regulation of UCP3 by nucleotides is different from regulation of UCP1
KS Echtay, Q Liu, T Caskey, E Winkler, K Frischmuth, M Bienengräber, ...
FEBS letters 450 (1-2), 8-12, 1999
781999
Coenzyme Q induces GDP-sensitive proton conductance in kidney mitochondria
KS Echtay, MD Brand
Biochemical society transactions 29 (6), 763-768, 2001
672001
Ubiquinone is not required for proton conductance by uncoupling protein 1 in yeast mitochondria
TC Esteves, KS Echtay, T Jonassen, CF Clarke, MD Brand
Biochemical Journal 379 (2), 309-315, 2004
602004
Mutagenesis of the uncoupling protein of brown adipose tissue. Neutralization of E190 largely abolishes pH control of nucleotide binding
KS Echtay, M Bienengraeber, M Klingenberg
Biochemistry 36 (27), 8253-8260, 1997
591997
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