Genetic architecture of complex traits: large phenotypic effects and pervasive epistasis H Shao, LC Burrage, DS Sinasac, AE Hill, SR Ernest, W O'Brien, ... Proceedings of the National Academy of Sciences 105 (50), 19910-19914, 2008 | 316 | 2008 |
IGF‐1 and bone: new discoveries from mouse models S Yakar, HW Courtland, D Clemmons Journal of Bone and Mineral Research 25 (12), 2543-2552, 2010 | 177 | 2010 |
Serum IGF‐1 determines skeletal strength by regulating subperiosteal expansion and trait interactions S Yakar, E Canalis, H Sun, W Mejia, Y Kawashima, P Nasser, ... Journal of Bone and Mineral Research 24 (8), 1481-1492, 2009 | 123 | 2009 |
Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility KJ Jepsen, B Hu, SM Tommasini, HW Courtland, C Price, CJ Terranova, ... Mammalian genome 18, 492-507, 2007 | 92 | 2007 |
Measuring the dynamic mechanical response of hydrated mouse bone by nanoindentation S Pathak, JG Swadener, SR Kalidindi, HW Courtland, KJ Jepsen, ... Journal of the Mechanical Behavior of Biomedical Materials 4 (1), 34-43, 2011 | 90 | 2011 |
Elevated serum levels of IGF‐1 are sufficient to establish normal body size and skeletal properties even in the absence of tissue IGF‐1 S Elis, HW Courtland, Y Wu, CJ Rosen, H Sun, KJ Jepsen, RJ Majeska, ... Journal of Bone and Mineral Research 25 (6), 1257-1266, 2010 | 83 | 2010 |
Defining nasal cartilage elasticity RW Westreich, HW Courtland, P Nasser, K Jepsen, W Lawson Archives of Facial Plastic Surgery, 2007 | 79 | 2007 |
Serum IGF-1 affects skeletal acquisition in a temporal and compartment-specific manner HW Courtland, S Elis, Y Wu, H Sun, CJ Rosen, KJ Jepsen, S Yakar PloS one 6 (3), e14762, 2011 | 52 | 2011 |
Growth hormone mediates pubertal skeletal development independent of hepatic IGF‐1 production HW Courtland, H Sun, M Beth‐On, Y Wu, S Elis, CJ Rosen, S Yakar Journal of bone and mineral research 26 (4), 761-768, 2011 | 49 | 2011 |
Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains KJ Jepsen, B Hu, SM Tommasini, HW Courtland, C Price, M Cordova, ... Mammalian Genome 20, 21-33, 2009 | 49 | 2009 |
Fourier transform infrared imaging microspectroscopy and tissue-level mechanical testing reveal intraspecies variation in mouse bone mineral and matrix composition HW Courtland, P Nasser, AB Goldstone, L Spevak, AL Boskey, KJ Jepsen Calcified tissue international 83, 342-353, 2008 | 49 | 2008 |
Elevated serum IGF‐1 levels synergize PTH action on the skeleton only when the tissue IGF‐1 axis is intact S Elis, HW Courtland, Y Wu, JC Fritton, H Sun, CJ Rosen, S Yakar Journal of Bone and Mineral Research 25 (9), 2051-2058, 2010 | 46 | 2010 |
Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging HW Courtland, OD Kennedy, Y Wu, Y Gao, H Sun, MB Schaffler, S Yakar Age 35, 1691-1703, 2013 | 40 | 2013 |
Sex‐specific regulation of body size and bone slenderness by the acid labile subunit HW Courtland, V DeMambro, J Maynard, H Sun, S Elis, C Rosen, S Yakar Journal of Bone and Mineral Research 25 (9), 2059-2068, 2010 | 34 | 2010 |
Intermittent PTH administration and mechanical loading are anabolic for periprosthetic cancellous bone MJ Grosso, HW Courtland, X Yang, JP Sutherland, K Stoner, J Nguyen, ... Journal of Orthopaedic Research 33 (2), 163-173, 2015 | 33 | 2015 |
Unbound (bioavailable) IGF1 enhances somatic growth S Elis, Y Wu, HW Courtland, D Cannata, H Sun, M Beth-On, C Liu, ... Disease models & mechanisms 4 (5), 649-658, 2011 | 33 | 2011 |
Increased serum IGF‐1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 … S Elis, YJ Wu, HW Courtland, H Sun, CJ Rosen, ML Adamo, S Yakar Aging cell 10 (3), 547-550, 2011 | 31 | 2011 |
The Insulin-like Growth Factor-1 Binding Protein Acid-labile Subunit Alters Mesenchymal Stromal Cell Fate 2 JC Fritton, Y Kawashima, W Mejia, HW Courtland, S Elis, H Sun, Y Wu, ... Journal of Biological Chemistry 285 (7), 4709-4714, 2010 | 30 | 2010 |
Genetically determined phenotype covariation networks control bone strength KJ Jepsen, HW Courtland, JH Nadeau Journal of Bone and Mineral Research 25 (7), 1581-1593, 2010 | 29 | 2010 |
Flapping flexible fish: Periodic and secular body reconfigurations in swimming lamprey, Petromyzon marinus RG Root, HW Courtland, W Shepherd, JH Long Animal Locomotion, 141-159, 2010 | 18 | 2010 |