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FBXW7 modulates cellular stress response and metastatic potential through ​HSF1 post-translational modification
IA N Kourtis, RS Moubarak, B Aranda-Orgilles, K Lui, IT Aydin, T Trimarchi ...
Nature Cell Biology, 322–332, 2015
1452015
GAB2—a scaffolding protein in cancer
SJ Adams, IT Aydin, JT Celebi
Molecular Cancer Research 10 (10), 1265-1270, 2012
1002012
FBXW7 Mutations in Melanoma and a New Therapeutic Paradigm
IT Aydin, RD Melamed, SJ Adams, M Castillo-Martin, A Demir, D Bryk, ...
Journal of the National Cancer Institute 106 (6), dju107, 2014
932014
Genomic characterization of dysplastic nevi unveils implications for diagnosis of melanoma
RD Melamed, IT Aydin, GS Rajan, R Phelps, DN Silvers, KJ Emmett, ...
Journal of Investigative Dermatology 137 (4), 905-909, 2017
632017
Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation
B Badal, A Solovyov, S Di Cecilia, JM Chan, LW Chang, R Iqbal, IT Aydin, ...
JCI insight 2 (9), 2017
552017
RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice
K Schouwey, IT Aydin, F Radtke, F Beermann
Oncogene 30 (3), 313-322, 2011
422011
Coat color dilution in mice because of inactivation of the melanoma antigen MART‐1
IT Aydin, E Hummler, NPM Smit, F Beermann
Pigment cell & melanoma research 25 (1), 37-46, 2012
302012
A mart‐1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium
IT Aydin, F Beermann
Genesis 49 (5), 403-409, 2011
242011
FBXW 7 regulates a mitochondrial transcription program by modulating MITF
F Abbate, B Badal, K Mendelson, IT Aydin, MN Serasinghe, R Iqbal, ...
Pigment cell & melanoma research 31 (5), 636-640, 2018
152018
Alternatively spliced Robo2 isoforms in zebrafish and rat
E Dalkic, C Kuscu, C Sucularli, IT Aydin, KC Akcali, O Konu
Development Genes and Evolution 216, 555-563, 2006
132006
Cloning and expression profile of FLT3 gene during progenitor cell‐dependent liver regeneration
IT Aydin, Z Tokcaer, A Dalgic, O Konu, KC Akcali
Journal of gastroenterology and hepatology 22 (12), 2181-2188, 2007
102007
FBXW7 inactivation in a BrafV600E-driven mouse model leads to melanoma development
IT Aydin, F Abbate, GS Rajan, B Badal, I Aifantis, G Desman, JT Celebi
Pigment cell & melanoma research 30 (6), 571, 2017
82017
Melanocyte and RPE‐specific expression in transgenic mice by mouse MART‐1/Melan‐A/mlana regulatory sequences
IT Aydin, F Beermann
Pigment cell & melanoma research 22 (6), 854-856, 2009
62009
Expression from a bacterial artificial chromosome containing the Dct gene locus
F Murisier, IT Aydin, S Guichard, S Brunschwiler, F Beermann
Pigment cell & melanoma research 21 (2), 212-215, 2008
32008
AORTIC VASCULAR SMOOTH MUCLE CELL APOPTOSIS IN PATIENTS WITH TYPE-A AORTIC DISSECTION
AR AKAR, KC AKÇALI, S DURDU, IT AYDIN, F ÇİVRİL, R TAŞÖZ, ...
Turkish Journal of Vascular Surgery 14 (2), 2005
32005
First-in-human phase Ib study of ATRC-101, an engineered version of a patient-derived antibody targeting a tumor-restricted ribonucleoprotein complex.
JE Benjamin, N Higgins, C Millward, J Defalco, A Manning-Bog, IT Aydin, ...
Journal of Clinical Oncology 38 (15_suppl), TPS3168-TPS3168, 2020
22020
Expressional and functional profile of TRPC gene family in aging rat aorta
Y Erac, C Selli, IT Aydin, B Kosova, CK Akcali, M Tosun
Blackwell Publishing, 2006
22006
Mobilization of innate and adaptive antitumor immune responses by the RNP-targeting antibody ATRC-101
A Scholz, J DeFalco, Y Leung, IT Aydin, CJ Czupalla, W Cao, D Santos, ...
Proceedings of the National Academy of Sciences 119 (19), e2123483119, 2022
12022
Abstract CT203: First-in-human phase 1b study of ATRC-101, a patient-derived antibody with a tumor-specific target, as monotherapy or in combination with pembrolizumab, in …
JE Benjamin, N Higgins, C Millward, J DeFalco, A Manning-Bog, IT Aydin, ...
Cancer Research 81 (13_Supplement), CT203-CT203, 2021
12021
A human H1-HBB11-GFP reporter embryonic stem cell line (WAe001-A-2) generated using TALEN-based genome editing
V Alexeeva, IT Aydin, C Schaniel, AW Stranahan, SL D'Souza, JJ Bieker
Stem cell research 45, 101837, 2020
12020
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