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Markus Hecht
Markus Hecht
Saarland University Medical Center, Homburg
Bestätigte E-Mail-Adresse bei uks.eu - Startseite
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Chemoradiation increases PD-L1 expression in certain melanoma and glioblastoma cells
A Derer, M Spiljar, M Bäumler, M Hecht, R Fietkau, B Frey, US Gaipl
Frontiers in immunology 7, 610, 2016
1352016
Radiosensitization by BRAF inhibitor therapy—mechanism and frequency of toxicity in melanoma patients
M Hecht, L Zimmer, C Loquai, C Weishaupt, R Gutzmer, B Schuster, ...
Annals of Oncology 26 (6), 1238-1244, 2015
1342015
PD-L1 is upregulated by radiochemotherapy in rectal adenocarcinoma patients and associated with a favourable prognosis
M Hecht, M Büttner-Herold, K Erlenbach-Wünsch, M Haderlein, R Croner, ...
European journal of cancer 65, 52-60, 2016
1302016
Immune modulatory effects of radiotherapy as basis for well-reasoned radioimmunotherapies
M Rückert, L Deloch, R Fietkau, B Frey, M Hecht, US Gaipl
Strahlentherapie und Onkologie 194 (6), 509-519, 2018
1092018
Radiotherapy and the immune system: More than just immune suppression
M Rückert, AS Flohr, M Hecht, US Gaipl
Stem Cells 39 (9), 1155-1165, 2021
772021
CD8+ and regulatory T cells differentiate tumor immune phenotypes and predict survival in locally advanced head and neck cancer
A Echarti, M Hecht, M Büttner-Herold, M Haderlein, A Hartmann, ...
Cancers 11 (9), 1398, 2019
772019
Safety and efficacy of single cycle induction treatment with cisplatin/docetaxel/durvalumab/tremelimumab in locally advanced HNSCC: first results of CheckRad-CD8
M Hecht, AO Gostian, M Eckstein, S Rutzner, J von der Grün, T Illmer, ...
Journal for immunotherapy of cancer 8 (2), 2020
612020
Efavirenz has the highest anti-proliferative effect of non-nucleoside reverse transcriptase inhibitors against pancreatic cancer cells
M Hecht, S Erber, T Harrer, H Klinker, T Roth, H Parsch, N Fiebig, ...
PLoS One 10 (6), e0130277, 2015
582015
Radiomics to predict outcomes and abscopal response of patients with cancer treated with immunotherapy combined with radiotherapy using a validated signature of CD8 cells
R Sun, N Sundahl, M Hecht, F Putz, A Lancia, A Rouyar, M Milic, A Carré, ...
Journal for Immunotherapy of Cancer 8 (2), 2020
562020
Cytotoxic effect of efavirenz is selective against cancer cells and associated with the cannabinoid system
M Hecht, T Harrer, M Büttner, M Schwegler, S Erber, R Fietkau, LV Distel
Aids 27 (13), 2031-2040, 2013
552013
Randomized phase III trial of induction chemotherapy followed by chemoradiotherapy or chemotherapy alone for nonresectable locally advanced pancreatic cancer: First results of …
R Fietkau, M Ghadimi, R Grützmann, UA Wittel, L Jacobasch, W Uhl, ...
Journal of Clinical Oncology 40 (16_suppl), 4008-4008, 2022
532022
Increased skin and mucosal toxicity in the combination of vemurafenib with radiation therapy
R Merten, M Hecht, M Haderlein, L Distel, R Fietkau, L Heinzerling, ...
Strahlentherapie und Onkologie 190 (12), 1169, 2014
472014
Immune biological rationales for the design of combined radio-and immunotherapies
M Hader, B Frey, R Fietkau, M Hecht, US Gaipl
Cancer Immunology, Immunotherapy 69 (2), 293-306, 2020
442020
Prospective development and validation of a liquid immune profile-based signature (LIPS) to predict response of patients with recurrent/metastatic cancer to immune checkpoint …
JG Zhou, AJ Donaubauer, B Frey, I Becker, S Rutzner, M Eckstein, R Sun, ...
Journal for Immunotherapy of Cancer 9 (2), 2021
412021
Clinical outcome of concomitant vs interrupted BRAF inhibitor therapy during radiotherapy in melanoma patients
M Hecht, F Meier, L Zimmer, B Polat, C Loquai, C Weishaupt, A Forschner, ...
British journal of cancer 118 (6), 785-792, 2018
412018
Randomized phase-III-trial of concurrent chemoradiation for locally advanced head and neck cancer comparing dose reduced radiotherapy with paclitaxel/cisplatin to standard …
R Fietkau, M Hecht, B Hofner, D Lubgan, H Iro, O Gefeller, C Rödel, ...
Radiotherapy and Oncology 144, 209-217, 2020
362020
Spatial distribution of FoxP3+ and CD8+ tumour infiltrating T cells reflects their functional activity
R Posselt, K Erlenbach-Wünsch, M Haas, J JeΔberger, M Büttner-Herold, ...
Oncotarget 7 (37), 60383, 2016
352016
Targeted therapy, chemotherapy, immunotherapy and novel treatment options for different subtypes of salivary gland cancer
SK Mueller, M Haderlein, S Lettmaier, A Agaimy, F Haller, M Hecht, ...
Journal of Clinical Medicine 11 (3), 720, 2022
332022
Impact of postoperative radiotherapy and HER2/new overexpression in salivary duct carcinoma
M Haderlein, C Scherl, S Semrau, S Lettmaier, M Hecht, R Erber, H Iro, ...
Strahlentherapie und Onkologie 193 (11), 961, 2017
332017
Palbociclib induces senescence in melanoma and breast cancer cells and leads to additive growth arrest in combination with irradiation
T Jost, L Heinzerling, R Fietkau, M Hecht, LV Distel
Frontiers in Oncology 11, 740002, 2021
322021
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