| Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity M Hoffmann, H Hofmann-Winkler, JC Smith, N Krüger, P Arora, ... EBioMedicine 65, 2021 | 344 | 2021 |
| Alpha 1 antitrypsin is an inhibitor of the SARS-CoV-2–priming protease TMPRSS2 NP Azouz, AM Klingler, V Callahan, IV Akhrymuk, K Elez, L Raich, ... Pathogens And Immunity 6 (1), 55, 2021 | 115 | 2021 |
| Molecular-scale ligand effects in small gold–thiolate nanoclusters DM Chevrier, L Raich, C Rovira, A Das, Z Luo, Q Yao, A Chatt, J Xie, R Jin, ... Journal of the American Chemical Society 140 (45), 15430-15436, 2018 | 99 | 2018 |
| Molecular mechanism of inhibiting the SARS-CoV-2 cell entry facilitator TMPRSS2 with camostat and nafamostat T Hempel, L Raich, S Olsson, NP Azouz, AM Klingler, M Hoffmann, ... Chemical Science 12 (3), 983-992, 2021 | 81 | 2021 |
| 1, 6-Cyclophellitol cyclosulfates: a new class of irreversible glycosidase inhibitor M Artola, L Wu, MJ Ferraz, CL Kuo, L Raich, IZ Breen, WA Offen, ... ACS central science 3 (7), 784-793, 2017 | 76 | 2017 |
| The complete conformational free energy landscape of β-xylose reveals a two-fold catalytic itinerary for β-xylanases J Iglesias-Fernández, L Raich, A Ardèvol, C Rovira Chemical science 6 (2), 1167-1177, 2015 | 62 | 2015 |
| A trapped covalent intermediate of a glycoside hydrolase on the pathway to transglycosylation. insights from experiments and quantum mechanics/molecular mechanics simulations L Raich, V Borodkin, W Fang, J Castro-Lopez, DMF van Aalten, ... Journal of the American Chemical Society 138 (10), 3325-3332, 2016 | 58 | 2016 |
| Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes SP Schröder, C De Boer, NGS McGregor, RJ Rowland, O Moroz, ... ACS central science 5 (6), 1067-1078, 2019 | 55 | 2019 |
| A β-mannanase with a lysozyme-like fold and a novel molecular catalytic mechanism Y Jin, M Petricevic, A John, L Raich, H Jenkins, L Portela De Souza, ... ACS central science 2 (12), 896-903, 2016 | 55 | 2016 |
| An epoxide intermediate in glycosidase catalysis LF Sobala, G Speciale, S Zhu, L Raich, N Sannikova, AJ Thompson, ... ACS central science 6 (5), 760-770, 2020 | 50 | 2020 |
| Enzymatic cleavage of glycosidic bonds: strategies on how to set up and control a QM/MM metadynamics simulation L Raich, A Nin-Hill, A Ardèvol, C Rovira Methods in enzymology 577, 159-183, 2016 | 45 | 2016 |
| Palladium-mediated enzyme activation suggests multiphase initiation of glycogenesis MK Bilyard, HJ Bailey, L Raich, MA Gafitescu, T Machida, ... Nature 563 (7730), 235-240, 2018 | 44 | 2018 |
| Precise probing of residue roles by post-translational β, γ-C, N aza-Michael mutagenesis in enzyme active sites J Dadová, KJ Wu, PG Isenegger, JC Errey, GJL Bernardes, JM Chalker, ... ACS central science 3 (11), 1168-1173, 2017 | 43 | 2017 |
| Structural and mechanistic insights into the catalytic-domain-mediated short-range glycosylation preferences of GalNAc-T4 M de Las Rivas, EJ Paul Daniel, H Coelho, E Lira-Navarrete, L Raich, ... ACS Central Science 4 (9), 1274-1290, 2018 | 42 | 2018 |
| Carba-cyclophellitols are neutral retaining-glucosidase inhibitors TJM Beenakker, DPA Wander, WA Offen, M Artola, L Raich, MJ Ferraz, ... Journal of the American Chemical Society 139 (19), 6534-6537, 2017 | 41 | 2017 |
| Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine. 2021; 65: 103255 M Hoffmann, H Hofmann-Winkler, JC Smith, N Krüger, P Arora, ... DOI 10 (2020.08), 05.237651, 2021 | 37 | 2021 |
| Modeling catalytic reaction mechanisms in glycoside hydrolases J Coines, L Raich, C Rovira Current Opinion in Chemical Biology 53, 183-191, 2019 | 37 | 2019 |
| A Single Point Mutation Converts GH84 O-GlcNAc Hydrolases into Phosphorylases: Experimental and Theoretical Evidence D Teze, J Coines, L Raich, V Kalichuk, C Solleux, C Tellier, C André-Miral, ... Journal of the American Chemical Society 142 (5), 2120-2124, 2020 | 32 | 2020 |
| Discovery of a hidden transient state in all bromodomain families L Raich, K Meier, J Günther, CD Christ, F Noé, S Olsson Proceedings of the National Academy of Sciences 118 (4), e2017427118, 2021 | 29 | 2021 |
| Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity. EBioMedicine 65: 103255 M Hoffmann, H Hofmann-Winkler, JC Smith, N Krüger, P Arora, ... J. EBIOM, 2021 | 24 | 2021 |
Carme RoviraICREA Research Professor at University of BarcelonaVerified email at ub.edu
