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Felipe de Sousa e Melo
Felipe de Sousa e Melo
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Zitiert von
Zitiert von
Jahr
The consensus molecular subtypes of colorectal cancer
J Guinney, R Dienstmann, X Wang, A De Reynies, A Schlicker, ...
Nature medicine 21 (11), 1350-1356, 2015
34212015
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment
L Vermeulen, F De Sousa E Melo, M Van Der Heijden, K Cameron, ...
Nature cell biology 12 (5), 468-476, 2010
19082010
Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity
L Vermeulen, M Todaro, F de Sousa Mello, MR Sprick, K Kemper, ...
Proceedings of the National Academy of Sciences 105 (36), 13427-13432, 2008
8482008
Poor-prognosis colon cancer is defined by a molecularly distinct subtype and develops from serrated precursor lesions
F De Sousa E Melo, X Wang, M Jansen, E Fessler, A Trinh, ...
Nature medicine 19 (5), 614-618, 2013
7652013
Cancer Stem Cell Niche: The Place to BeThe Cancer Stem Cell Niche
T Borovski, F De Sousa E Melo, L Vermeulen, JP Medema
Cancer research 71 (3), 634-639, 2011
5912011
The gut microbiota plays a protective role in the host defence against pneumococcal pneumonia
TJ Schuijt, JM Lankelma, BP Scicluna, FS e Melo, JJTH Roelofs, ...
Gut 65 (4), 575-583, 2016
5342016
A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer
F de Sousa e Melo, AV Kurtova, JM Harnoss, N Kljavin, JD Hoeck, J Hung, ...
Nature 543 (7647), 676-680, 2017
4612017
The developing cancer stem-cell model: clinical challenges and opportunities
L Vermeulen, FS e Melo, DJ Richel, JP Medema
The lancet oncology 13 (2), e83-e89, 2012
4342012
Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients
EM Felipe de Sousa, S Colak, J Buikhuisen, J Koster, K Cameron, ...
Cell stem cell 9 (5), 476-485, 2011
3212011
Cancer heterogeneity—a multifaceted view
FDSE Melo, L Vermeulen, E Fessler, JP Medema
EMBO reports 14 (8), 686-695, 2013
2592013
Targeting Wnt Signaling in Colon Cancer Stem CellsWnt in Colon Cancer Stem Cells
E de Sousa, L Vermeulen, D Richel, JP Medema
Clinical Cancer Research 17 (4), 647-653, 2011
2402011
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
EE Storm, S Durinck, F de Sousa E Melo, J Tremayne, N Kljavin, C Tan, ...
Nature 529 (7584), 97-100, 2016
1992016
Wnt signaling in cancer stem cell biology
F De Sousa e Melo, L Vermeulen
Cancers 8 (7), 60, 2016
1752016
Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by ImmunohistochemistryColorectal Cancer Subtypes by Immunohistochemistry
A Trinh, K Trumpi, F De Sousa E Melo, X Wang, JH De Jong, E Fessler, ...
Clinical cancer research 23 (2), 387-398, 2017
1362017
Cancer stem cell dynamics in tumor progression and metastasis: is the microenvironment to blame?
E Fessler, FE Dijkgraaf, EM Felipe De Sousa, JP Medema
Cancer letters 341 (1), 97-104, 2013
1332013
Stem cell functionality is microenvironmentally defined during tumour expansion and therapy response in colon cancer
KJ Lenos, DM Miedema, SC Lodestijn, LE Nijman, T van den Bosch, ...
Nature cell biology 20 (10), 1193-1202, 2018
1242018
TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype
E Fessler, J Drost, SR van Hooff, JF Linnekamp, X Wang, M Jansen, ...
EMBO molecular medicine 8 (7), 745-760, 2016
1242016
OTULIN limits cell death and inflammation by deubiquitinating LUBAC
K Heger, KE Wickliffe, A Ndoja, J Zhang, A Murthy, DL Dugger, ...
Nature 559 (7712), 120-124, 2018
1182018
Cellular plasticity in intestinal homeostasis and disease
FS e Melo, FJ de Sauvage
Cell Stem Cell 24 (1), 54-64, 2019
922019
Reconciliation of classification systems defining molecular subtypes of colorectal cancer: interrelationships and clinical implications
A Sadanandam, X Wang, F de Sousa E Melo, JW Gray, L Vermeulen, ...
Cell cycle 13 (3), 353-357, 2014
882014
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