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Luk H. Vandenberghe, Ph.D.
Luk H. Vandenberghe, Ph.D.
Grousbeck Family Chair in Gene Therapy, Associate Professor of Ophthalmology, Harvard University
Bestätigte E-Mail-Adresse bei meei.harvard.edu - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Clades of Adeno-associated viruses are widely disseminated in human tissues
G Gao, LH Vandenberghe, MR Alvira, Y Lu, R Calcedo, X Zhou, ...
Journal of virology 78 (12), 6381-6388, 2004
13812004
In vivo gene editing in dystrophic mouse muscle and muscle stem cells
M Tabebordbar, K Zhu, JKW Cheng, WL Chew, JJ Widrick, WX Yan, ...
Science 351 (6271), 407-411, 2016
12272016
Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses
R Calcedo, LH Vandenberghe, G Gao, J Lin, JM Wilson
The Journal of infectious diseases 199 (3), 381-390, 2009
8872009
New recombinant serotypes of AAV vectors
G Gao, LH Vandenberghe, JM Wilson
Current gene therapy 5 (3), 285-297, 2005
6182005
Adeno-associated viruses undergo substantial evolution in primates during natural infections
G Gao, MR Alvira, S Somanathan, Y Lu, LH Vandenberghe, JJ Rux, ...
Proceedings of the National Academy of Sciences 100 (10), 6081-6086, 2003
4722003
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells
G Simmons, JD Reeves, CC Grogan, LH Vandenberghe, F Baribaud, ...
Virology 305 (1), 115-123, 2003
4522003
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses therefor
JM Wilson, G Gao, MR Alvira, LH Vandenberghe
US Patent 7,906,111, 2011
4262011
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale
M Lock, M Alvira, LH Vandenberghe, A Samanta, J Toelen, Z Debyser, ...
Human gene therapy 21 (10), 1259-1271, 2010
4172010
Therapeutic AAV gene transfer to the nervous system: a clinical reality
E Hudry, LH Vandenberghe
Neuron 101 (5), 839-862, 2019
3722019
In silico reconstruction of the viral evolutionary lineage yields a potent gene therapy vector
E Zinn, S Pacouret, V Khaychuk, HT Turunen, LS Carvalho, ...
Cell reports 12 (6), 1056-1068, 2015
3712015
Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain
JM Taymans, LH Vandenberghe, CVD Haute, I Thiry, CM Deroose, ...
Human gene therapy 18 (3), 195-206, 2007
3582007
A synthetic AAV vector enables safe and efficient gene transfer to the mammalian inner ear
LD Landegger, B Pan, C Askew, SJ Wassmer, SD Gluck, A Galvin, ...
Nature biotechnology 35 (3), 280-284, 2017
3272017
Novel adeno-associated virus serotypes efficiently transduce murine photoreceptors
M Allocca, C Mussolino, M Garcia-Hoyos, D Sanges, C Iodice, M Petrillo, ...
Journal of virology 81 (20), 11372-11380, 2007
3112007
Gene therapy restores auditory and vestibular function in a mouse model of Usher syndrome type 1c
B Pan, C Askew, A Galvin, S Heman-Ackah, Y Asai, AA Indzhykulian, ...
Nature biotechnology 35 (3), 264-272, 2017
2842017
Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver
E Breous, S Somanathan, LH Vandenberghe, JM Wilson
Hepatology 50 (2), 612-621, 2009
2692009
Progress in gene therapy for neurological disorders
M Simonato, J Bennett, NM Boulis, MG Castro, DJ Fink, WF Goins, ...
Nature Reviews Neurology 9 (5), 277-291, 2013
2672013
Dosage thresholds for AAV2 and AAV8 photoreceptor gene therapy in monkey
LH Vandenberghe, P Bell, AM Maguire, CN Cearley, R Xiao, R Calcedo, ...
Science translational medicine 3 (88), 88ra54-88ra54, 2011
2622011
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid
LH Vandenberghe, L Wang, S Somanathan, Y Zhi, J Figueredo, ...
Nature medicine 12 (8), 967-971, 2006
2512006
The AAV9 receptor and its modification to improve in vivo lung gene transfer in mice
CL Bell, LH Vandenberghe, P Bell, MP Limberis, GP Gao, K Van Vliet, ...
The Journal of clinical investigation 121 (6), 2427-2435, 2011
2392011
Expanded repertoire of AAV vector serotypes mediate unique patterns of transduction in mouse brain
CN Cearley, LH Vandenberghe, MK Parente, ER Carnish, JM Wilson, ...
Molecular therapy 16 (10), 1710-1718, 2008
2182008
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