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Robert Hopewell
Robert Hopewell
Radiochemist, McGill University
Bestätigte E-Mail-Adresse bei mcgill.ca - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Azapeptides and their therapeutic potential
C Proulx, D Sabatino, R Hopewell, J Spiegel, Y García Ramos, WD Lubell
Future medicinal chemistry 3 (9), 1139-1164, 2011
1912011
18F-MK-6240 PET for early and late detection of neurofibrillary tangles
TA Pascoal, J Therriault, AL Benedet, M Savard, FZ Lussier, M Chamoun, ...
Brain 143 (9), 2818-2830, 2020
1652020
In vivo quantification of neurofibrillary tangles with [18F]MK-6240
TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ...
Alzheimer's research & therapy 10, 1-14, 2018
1502018
Syntheses and evaluation of carbon-11-and fluorine-18-radiolabeled pan-tropomyosin receptor kinase (Trk) inhibitors: exploration of the 4-aza-2-oxindole scaffold as Trk PET …
V Bernard-Gauthier, A Aliaga, A Aliaga, M Boudjemeline, R Hopewell, ...
ACS Chemical Neuroscience 6 (2), 260-276, 2015
312015
N-Aminoimidazolidin-2-one Peptidomimetics
ND Doan, R Hopewell, WD Lubell
Organic letters 16 (8), 2232-2235, 2014
192014
[11C]Martinostat PET analysis reveals reduced HDAC I availability in Alzheimer’s disease
TA Pascoal, M Chamoun, E Lax, HY Wey, M Shin, KP Ng, MS Kang, ...
nature communications 13 (1), 4171, 2022
162022
Characterization of scintillating fibers for use as positron detector in positron emission tomography
V Turgeon, G Kertzscher, L Carroll, R Hopewell, G Massarweh, SA Enger
Physica Medica 65, 114-120, 2019
152019
Highly efficient solid phase supported radiosynthesis of [11C]PiB using tC18 cartridge as a “3‐in‐1” production entity
M Boudjemeline, R Hopewell, PL Rochon, D Jolly, I Hammami, ...
Journal of Labelled Compounds and Radiopharmaceuticals 60 (14), 632-638, 2017
142017
MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription
MF Niedzielski, R Hopewell, Z Ismail, MC Estable
International journal of biological sciences 3 (4), 225, 2007
132007
1H-Pyrroles
W Lubell, D Saint-Cyr, J Dufour-Gallant, R Hopewell, N Boutard, ...
Science of Synthesis 1, 157-388, 2013
122013
CSF tau368/total-tau ratio reflects cognitive performance and neocortical tau better compared to p-tau181 and p-tau217 in cognitively impaired individuals
J Simrén, WS Brum, NJ Ashton, AL Benedet, TK Karikari, H Kvartsberg, ...
Alzheimer's Research & Therapy 14 (1), 192, 2022
102022
A simplified radiosynthesis of [18F]MK‐6240 for tau PET imaging
R Hopewell, K Ross, A Kostikov, TA Pascoal, T Alberti, ...
Journal of Labelled Compounds and Radiopharmaceuticals 62 (2), 109-114, 2019
102019
In vivo quantification of neurofibrillary tangles with [(18) F] MK-6240. Alzheimers Res Ther 10: 74
TA Pascoal, M Shin, MS Kang, M Chamoun, D Chartrand, ...
92018
Development of “[11C] kits” for a fast, efficient and reliable production of carbon-11 labeled radiopharmaceuticals for Positron Emission Tomography
D Jolly, R Hopewell, M Kovacevic, QY Li, JP Soucy, A Kostikov
Applied radiation and isotopes 121, 76-81, 2017
82017
Co-registration of imaging modalities (MRI, CT and PET) to perform frameless stereotaxic robotic injections in the common marmoset
C Kwan, MS Kang, SG Nuara, JC Gourdon, D Bédard, CL Tardif, ...
Neuroscience 480, 143-154, 2022
62022
Preliminary Evaluations of [11C]Verubulin: Implications for Microtubule Imaging With PET
A Lindberg, AV Mossine, A Aliaga, R Hopewell, G Massarweh, ...
Frontiers in Neuroscience 15, 725873, 2021
42021
Cryo-EM structure of Alzheimer’s disease tau filaments with PET ligand MK-6240
P Kunach, J Vaquer-Alicea, MS Smith, R Hopewell, J Monistrol, L Moquin, ...
bioRxiv, 2023
32023
Distribution of [11C]-JNJ-42491293 in the marmoset brain: a positron emission tomography study
MS Kang, A Hamadjida, D Bédard, SG Nuara, JC Gourdon, S Frey, ...
Naunyn-Schmiedeberg's Archives of Pharmacology 396 (9), 2095-2103, 2023
22023
Solid phase 11C-methylation, purification and formulation for the production of PET tracers
TA Singleton, M Boudjemeline, R Hopewell, D Jolly, H Bdair, A Kostikov
JoVE (Journal of Visualized Experiments), e60237, 2019
12019
Peptidomimetics comprising N-amino cyclic urea residues and uses thereof
WD Lubell, S Chemtob, H Ong, R Hopewell, C Proulx, K Beauregard, ...
US Patent 8,993,515, 2015
12015
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