| The Wnt/planar cell polarity protein-tyrosine kinase-7 (PTK7) is a highly efficient proteolytic target of membrane type-1 matrix metalloproteinase: implications in cancer and … VS Golubkov, AV Chekanov, P Cieplak, AE Aleshin, AV Chernov, W Zhu, ... Journal of Biological Chemistry 285 (46), 35740-35749, 2010 | 102 | 2010 |
| Transgenic overexpression of tissue‐nonspecific alkaline phosphatase (TNAP) in vascular endothelium results in generalized arterial calcification AY Savinov, M Salehi, MC Yadav, I Radichev, JL Millán, OV Savinova Journal of the American Heart Association 4 (12), e002499, 2015 | 89 | 2015 |
| Inflammatory proprotein convertase-matrix metalloproteinase proteolytic pathway in antigen-presenting cells as a step to autoimmune multiple sclerosis SA Shiryaev, AG Remacle, AY Savinov, AV Chernov, P Cieplak, ... Journal of biological chemistry 284 (44), 30615-30626, 2009 | 53 | 2009 |
| Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia F Romanelli, AM Corbo, M Salehi, MC Yadav, S Salman, D Petrosian, ... PloS one 12 (10), e0186426, 2017 | 52 | 2017 |
| Proteolysis of the membrane type-1 matrix metalloproteinase prodomain: implications for a two-step proteolytic processing and activation VS Golubkov, AV Chekanov, SA Shiryaev, AE Aleshin, BI Ratnikov, ... Journal of biological chemistry 282 (50), 36283-36291, 2007 | 42 | 2007 |
| Structure-based mutagenesis identifies important novel determinants of the NS2B cofactor of the West Nile virus two-component NS2B–NS3 proteinase I Radichev, SA Shiryaev, AE Aleshin, BI Ratnikov, JW Smith, ... Journal of general virology 89 (3), 636-641, 2008 | 38 | 2008 |
| New insights into immunotherapy strategies for treating autoimmune diabetes M Cabello-Olmo, M Araña, I Radichev, P Smith, E Huarte, M Barajas International journal of molecular sciences 20 (19), 4789, 2019 | 34 | 2019 |
| Initiation of DNA replication at a nuclear matrix‐attached chromatin fraction I Radichev, A Parashkevova, B Anachkova Journal of cellular physiology 203 (1), 71-77, 2005 | 34 | 2005 |
| Biochemical characterization of the cellular glycosylphosphatidylinositol-linked membrane type-6 matrix metalloproteinase IA Radichev, AG Remacle, SA Shiryaev, AN Purves, SL Johnson, ... Journal of biological chemistry 285 (21), 16076-16086, 2010 | 30 | 2010 |
| Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development IA Radichev, LV Maneva-Radicheva, C Amatya, C Parker, J Ellefson, ... Diabetes 63 (10), 3470-3482, 2014 | 28 | 2014 |
| Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase VS Golubkov, P Cieplak, AV Chekanov, BI Ratnikov, AE Aleshin, ... Journal of biological chemistry 285 (36), 27726-27736, 2010 | 27 | 2010 |
| Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor IA Radichev, J Yoon, DW Scott, K Griffin, AY Savinov Cellular immunology 358, 104224, 2020 | 23 | 2020 |
| Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus T Kolodka, ML Charles, A Raghavan, IA Radichev, C Amatya, J Ellefson, ... PloS one 9 (8), e103981, 2014 | 20 | 2014 |
| Loss of peripheral protection in pancreatic islets by proteolysis-driven impairment of VTCN1 (B7-H4) presentation is associated with the development of autoimmune diabetes IA Radichev, LV Maneva-Radicheva, C Amatya, M Salehi, C Parker, ... The Journal of Immunology 196 (4), 1495-1506, 2016 | 19 | 2016 |
| Genetic analysis of human Orc2 reveals specific domains that are required in vivo for assembly and nuclear localization of the origin recognition complex I Radichev, SW Kwon, Y Zhao, ML DePamphilis, A Vassilev Journal of biological chemistry 281 (32), 23264-23273, 2006 | 19 | 2006 |
| Dynamic interdomain interactions contribute to the inhibition of matrix metalloproteinases by tissue inhibitors of metalloproteinases AG Remacle, SA Shiryaev, IA Radichev, DV Rozanov, B Stec, ... Journal of Biological Chemistry 286 (23), 21002-21012, 2011 | 16 | 2011 |
| Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking … IA Radichev, AG Remacle, NE Sounni, SA Shiryaev, DV Rozanov, W Zhu, ... Biochemical Journal 420 (1), 37-47, 2009 | 16 | 2009 |
| Autoimmune diabetes is suppressed by treatment with recombinant human tissue kallikrein-1 L Maneva-Radicheva, C Amatya, C Parker, J Ellefson, I Radichev, ... PLoS One 9 (9), e107213, 2014 | 14 | 2014 |
| Use of induced pluripotent stem cells to build isogenic systems and investigate type 1 diabetes LH Armitage, SE Stimpson, KE Santostefano, L Sui, S Ogundare, ... Frontiers in endocrinology 12, 737276, 2021 | 9 | 2021 |
| The Type 1 Diabetes–Resistance Locus Idd22 Controls Trafficking of Autoreactive CTLs into the Pancreatic Islets of NOD Mice RL Whitener, L Gallo Knight, J Li, S Knapp, S Zhang, M Annamalai, ... The Journal of Immunology 199 (12), 3991-4000, 2017 | 9 | 2017 |
Alexei SavinovSanford Research/ USDBestätigte E-Mail-Adresse bei sanfordhealth.org
