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Dr. Kapil Gupta
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Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein
C Toelzer, K Gupta, SKN Yadav, U Borucu, AD Davidson, ...
Science 370 (6517), 725-730, 2020
3632020
The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147 receptor-mediated signalling: a potential non-infective mechanism of COVID-19 microvascular …
E Avolio, M Carrabba, R Milligan, M Kavanagh Williamson, AP Beltrami, ...
Clinical Science 135 (24), 2667-2689, 2021
1402021
Molecular simulations suggest vitamins, retinoids and steroids as ligands of the free fatty acid pocket of the SARS‐CoV‐2 Spike protein
DK Shoemark, CK Colenso, C Toelzer, K Gupta, RB Sessions, ...
Angewandte Chemie 133 (13), 7174-7186, 2021
882021
The MultiBac baculovirus/insect cell expression vector system for producing complex protein biologics
D Sari, K Gupta, DBTG Raj, A Aubert, P Drncová, F Garzoni, D Fitzgerald, ...
Advanced Technologies for Protein Complex Production and Characterization …, 2016
822016
Genetic code expansion for multiprotein complex engineering
C Koehler, PF Sauter, M Wawryszyn, GE Girona, K Gupta, JJM Landry, ...
Nature methods 13 (12), 997-1000, 2016
662016
TFIID enables RNA polymerase II promoter-proximal pausing
CB Fant, CB Levandowski, K Gupta, ZL Maas, J Moir, JD Rubin, A Sawyer, ...
Molecular cell 78 (4), 785-793. e8, 2020
602020
Zooming in on transcription preinitiation
K Gupta, D Sari-Ak, M Haffke, S Trowitzsch, I Berger
Journal of Molecular Biology 428 (12), 2581-2591, 2016
582016
Gene gymnastics: synthetic biology for baculovirus expression vector system engineering
LS Vijayachandran, DB Thimiri Govinda Raj, E Edelweiss, K Gupta, ...
Bioengineered 4 (5), 279-287, 2013
482013
The multiBac protein complex production platform at the EMBL
I Berger, F Garzoni, M Chaillet, M Haffke, K Gupta, A Aubert
JoVE (Journal of Visualized Experiments), e50159, 2013
452013
DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability
K Kramm, T Schröder, J Gouge, AM Vera, K Gupta, FB Heiss, T Liedl, ...
Nature communications 11 (1), 2828, 2020
442020
Chaperonin CCT checkpoint function in basal transcription factor TFIID assembly
SV Antonova, M Haffke, E Corradini, M Mikuciunas, TY Low, L Signor, ...
Nature structural & molecular biology 25 (12), 1119-1127, 2018
432018
Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID
K Gupta, AA Watson, T Baptista, E Scheer, AL Chambers, C Koehler, ...
Elife 6, e30395, 2017
372017
Sequential digestion with trypsin and elastase in cross-linking mass spectrometry
T Dau, K Gupta, I Berger, J Rappsilber
Analytical chemistry 91 (7), 4472-4478, 2019
342019
Multibac: baculovirus-mediated multigene DNA cargo delivery in insect and mammalian cells
K Gupta, C Tölzer, D Sari-Ak, DJ Fitzgerald, C Schaffitzel, I Berger
Viruses 11 (3), 198, 2019
342019
Pathogen-sugar interactions revealed by universal saturation transfer analysis
CJ Buchanan, B Gaunt, PJ Harrison, Y Yang, J Liu, A Khan, AM Giltrap, ...
Science 377 (6604), eabm3125, 2022
32*2022
More pieces to the puzzle: recent structural insights into class II transcription initiation
E Kandiah, S Trowitzsch, K Gupta, M Haffke, I Berger
Current opinion in structural biology 24, 91-97, 2014
322014
Young infants exhibit robust functional antibody responses and restrained IFN-γ production to SARS-CoV-2
A Goenka, A Halliday, M Gregorova, E Milodowski, A Thomas, ...
Cell Reports Medicine 2 (7), 2021
292021
Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2
K Gupta, C Toelzer, MK Williamson, DK Shoemark, ASF Oliveira, ...
Nature communications 13 (1), 222, 2022
26*2022
TBPL2/TFIIA complex establishes the maternal transcriptome through oocyte-specific promoter usage
C Yu, N Cvetesic, V Hisler, K Gupta, T Ye, E Gazdag, L Negroni, ...
Nature Communications 11 (1), 6439, 2020
24*2020
Synthetic energy sensor AMPfret deciphers adenylate-dependent AMPK activation mechanism
M Pelosse, C Cottet-Rousselle, CM Bidan, A Dupont, K Gupta, I Berger, ...
Nature communications 10 (1), 1038, 2019
242019
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