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Michael Flossdorf
Michael Flossdorf
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Year
Fundamental properties of unperturbed haematopoiesis from stem cells in vivo
K Busch, K Klapproth, M Barile, M Flossdorf, T Holland-Letz, ...
Nature 518 (7540), 542-546, 2015
7512015
Disparate individual fates compose robust CD8+ T cell immunity
VR Buchholz, M Flossdorf, I Hensel, L Kretschmer, B Weissbrich, P Gräf, ...
Science 340 (6132), 630-635, 2013
4452013
The microRNA miR-182 is induced by IL-2 and promotes clonal expansion of activated helper T lymphocytes
AB Stittrich, C Haftmann, E Sgouroudis, AA Kühl, AN Hegazy, I Panse, ...
Nature immunology 11 (11), 1057-1062, 2010
3872010
Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8+ central memory T cells
P Graef, VR Buchholz, C Stemberger, M Flossdorf, L Henkel, ...
Immunity 41 (1), 116-126, 2014
3502014
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
D Busse, M de la Rosa, K Hobiger, K Thurley, M Flossdorf, A Scheffold, ...
Proceedings of the National Academy of Sciences 107 (7), 3058-3063, 2010
3122010
Multi‐layered stochasticity and paracrine signal propagation shape the type‐I interferon response
U Rand, M Rinas, J Schwerk, G Nöhren, M Linnes, A Kröger, M Flossdorf, ...
Molecular systems biology 8 (1), 584, 2012
1742012
Identification of a tumor-reactive T-cell repertoire in the immune infiltrate of patients with resectable pancreatic ductal adenocarcinoma
I Poschke, M Faryna, F Bergmann, M Flossdorf, C Lauenstein, J Hermes, ...
OncoImmunology 5 (12), e1240859, 2016
872016
Differential expansion of T central memory precursor and effector subsets is regulated by division speed
L Kretschmer, M Flossdorf, J Mir, YL Cho, M Plambeck, I Treise, A Toska, ...
Nature Communications 11 (1), 1-12, 2020
662020
TCR Signal Quality Modulates Fate Decisions of Single CD4+ T Cells in a Probabilistic Manner
YL Cho, M Flossdorf, L Kretschmer, T Höfer, DH Busch, VR Buchholz
Cell Reports 20 (4), 806-818, 2017
622017
Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2’-O-Methylation Mutant
B Schmid, M Rinas, A Ruggieri, EG Acosta, M Bartenschlager, A Reuter, ...
PLoS Pathog 11 (12), e1005345, 2015
592015
Individual T Helper Cells Have a Quantitative Cytokine Memory
C Helmstetter, M Flossdorf, M Peine, A Kupz, J Zhu, AN Hegazy, ...
Immunity 42 (1), 108-122, 2015
562015
Distinct surface expression of activating receptor Ly49H drives differential expansion of NK cell clones upon murine cytomegalovirus infection
S Grassmann, LO Pachmayr, J Leube, L Mihatsch, I Andrae, ...
Immunity 50 (6), 1391-1400. e4, 2019
552019
CD8+ T cell diversification by asymmetric cell division
M Flossdorf, J Rössler, VR Buchholz, DH Busch, T Höfer
Nature immunology 16 (9), 891, 2015
532015
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
C Falcomatà, S Bärthel, SA Widholz, C Schneeweis, JJ Montero, A Toska, ...
Nature Cancer, 1-19, 2022
492022
The outcome of ex vivo TIL expansion is highly influenced by spatial heterogeneity of the tumor T-cell repertoire and differences in intrinsic in vitro growth capacity between …
IC Poschke, JC Hassel, A Rodriguez-Ehrenfried, KAM Lindner, ...
Clinical Cancer Research 26 (16), 4289-4301, 2020
492020
Early emergence of T central memory precursors programs clonal dominance during chronic viral infection
S Grassmann, L Mihatsch, J Mir, A Kazeroonian, R Rahimi, ...
Nature Immunology 21 (12), 1563-1573, 2020
432020
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection
S Flommersfeld, JP Böttcher, J Ersching, M Flossdorf, P Meiser, ...
Immunity 54 (10), 2288-2304. e7, 2021
402021
Antihypertensive drugs in COVID-19 infection
SJ Pinto-Sietsma, M Flossdorf, VR Buchholz, J Offerhaus, H Bleijendaal, ...
European Heart Journal-Cardiovascular Pharmacotherapy 6 (6), 415-416, 2020
332020
Hypercharge-universal topcolor
F Braam, M Flossdorf, RS Chivukula, S Di Chiara, EH Simmons
Physical Review D 77 (5), 055005, 2008
312008
Brief homogeneous TCR signals instruct common iNKT progenitors whose effector diversification is characterized by subsequent cytokine signaling
S Bortoluzzi, N Dashtsoodol, T Engleitner, C Drees, S Helmrath, J Mir, ...
Immunity 54 (11), 2497-2513. e9, 2021
252021
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