| Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis M Vujkovic, JM Keaton, JA Lynch, DR Miller, J Zhou, C Tcheandjieu, ... Nature genetics 52 (7), 680-691, 2020 | 515 | 2020 |
| The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 380 | 2020 |
| The effect of smoking on DNA methylation of peripheral blood mononuclear cells from African American women MV Dogan, B Shields, C Cutrona, L Gao, FX Gibbons, R Simons, ... BMC genomics 15, 1-13, 2014 | 224 | 2014 |
| Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells X Cai, L Gao, L Teng, J Ge, ZM Oo, AR Kumar, DG Gilliland, PJ Mason, ... Cell stem cell 17 (2), 165-177, 2015 | 213 | 2015 |
| Multiplexed in situ imaging mass cytometry analysis of the human endocrine pancreas and immune system in type 1 diabetes YJ Wang, D Traum, J Schug, L Gao, C Liu, MA Atkinson, AC Powers, ... Cell metabolism 29 (3), 769-783. e4, 2019 | 167 | 2019 |
| RUNX1 and the endothelial origin of blood L Gao, J Tober, P Gao, C Chen, K Tan, NA Speck Experimental hematology 68, 2-9, 2018 | 75 | 2018 |
| Single-cell transcriptomics of human islet ontogeny defines the molecular basis of β-cell dedifferentiation in T2D D Avrahami, YJ Wang, J Schug, E Feleke, L Gao, C Liu, A Naji, B Glaser, ... Molecular metabolism 42, 101057, 2020 | 74 | 2020 |
| Modeling disease progression using dynamics of pathway connectivity X Ma, L Gao, K Tan Bioinformatics 30 (16), 2343-2350, 2014 | 68 | 2014 |
| Identifying noncoding risk variants using disease-relevant gene regulatory networks L Gao, Y Uzun, P Gao, B He, X Ma, J Wang, S Han, K Tan Nature communications 9 (1), 702, 2018 | 59 | 2018 |
| Revealing pathway dynamics in heart diseases by analyzing multiple differential networks X Ma, L Gao, G Karamanlidis, P Gao, CF Lee, L Garcia-Menendez, R Tian, ... PLoS Computational Biology 11 (6), e1004332, 2015 | 51 | 2015 |
| Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells P Gao, C Chen, ED Howell, Y Li, J Tober, Y Uzun, B He, L Gao, Q Zhu, ... Genes & Development 34 (13-14), 950-964, 2020 | 42 | 2020 |
| Collapse of the hepatic gene regulatory network in the absence of FoxA factors Y Reizel, A Morgan, L Gao, Y Lan, E Manduchi, EL Waite, AW Wang, ... Genes & Development 34 (15-16), 1039-1050, 2020 | 41 | 2020 |
| Adaptation to chronic ER stress enforces pancreatic β-cell plasticity CW Chen, BJ Guan, MR Alzahrani, Z Gao, L Gao, S Bracey, J Wu, ... Nature communications 13 (1), 4621, 2022 | 39 | 2022 |
| FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity Y Reizel, A Morgan, L Gao, J Schug, S Mukherjee, MF García, G Donahue, ... Developmental Cell 56 (5), 602-612. e4, 2021 | 39 | 2021 |
| α Cell dysfunction in islets from nondiabetic, glutamic acid decarboxylase autoantibody–positive individuals NM Doliba, AV Rozo, J Roman, W Qin, D Traum, L Gao, J Liu, ... The Journal of clinical investigation 132 (11), 2022 | 33 | 2022 |
| 3D chromatin maps of the human pancreas reveal lineage-specific regulatory architecture of T2D risk C Su, L Gao, CL May, JA Pippin, K Boehm, M Lee, C Liu, MC Pahl, ... Cell metabolism 34 (9), 1394-1409. e4, 2022 | 28 | 2022 |
| Discover context-specific combinatorial transcription factor interactions by integrating diverse ChIP-Seq data sets L Teng, B He, P Gao, L Gao, K Tan Nucleic acids research 42 (4), e24-e24, 2014 | 25 | 2014 |
| Consortium YJ Wang, D Traum, J Schug, L Gao, C Liu H., Atkinson, MA, Powers, AC, Feldman, MD, Naji, A., et al, 769-783, 2019 | 23 | 2019 |
| CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation J Hsu, HT Huang, CT Lee, A Choudhuri, NK Wilson, BJ Abraham, ... Proceedings of the National Academy of Sciences 117 (38), 23626-23635, 2020 | 22 | 2020 |
| Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1 J Tober, MMW Maijenburg, Y Li, L Gao, BK Hadland, P Gao, K Minoura, ... Journal of Experimental Medicine 215 (2), 645-659, 2018 | 22 | 2018 |
Kai TanProfessor, Children's Hospital of Philadelphia, University of PennsylvaniaVerified email at chop.edu
