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Markus Blatter
Markus Blatter
Doctor of Biophysical Science, Novartis Pharma AG
Bestätigte E-Mail-Adresse bei novartis.com
Titel
Zitiert von
Zitiert von
Jahr
RNA recognition motifs: boring? Not quite
A Cléry, M Blatter, FHT Allain
Current opinion in structural biology 18 (3), 290-298, 2008
7692008
Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA
D Theler, C Dominguez, M Blatter, J Boudet, FHT Allain
Nucleic acids research 42 (22), 13911-13919, 2014
2442014
Kinetic models of cyclosporin A in polar and apolar environments reveal multiple congruent conformational states
J Witek, BG Keller, M Blatter, A Meissner, T Wagner, S Riniker
Journal of chemical information and modeling 56 (8), 1547-1562, 2016
1182016
rbFOX1/MBNL1 competition for CCUG RNA repeats binding contributes to myotonic dystrophy type 1/type 2 differences
C Sellier, E Cerro-Herreros, M Blatter, F Freyermuth, A Gaucherot, ...
Nature communications 9 (1), 2009, 2018
702018
Rationalization of the membrane permeability differences in a series of analogue cyclic decapeptides
J Witek, S Wang, B Schroeder, R Lingwood, A Dounas, HJ Roth, ...
Journal of chemical information and modeling 59 (1), 294-308, 2018
642018
Design and development of a cyclic decapeptide scaffold with suitable properties for bioavailability and oral exposure
M Fouché, M Schäfer, J Berghausen, S Desrayaud, M Blatter, P Piéchon, ...
ChemMedChem 11 (10), 1048-1059, 2016
642016
Interconversion rates between conformational states as rationale for the membrane permeability of cyclosporines
J Witek, M Mühlbauer, BG Keller, M Blatter, A Meissner, T Wagner, ...
ChemPhysChem 18 (23), 3309-3314, 2017
632017
Synergy between NMR measurements and MD simulations of protein/RNA complexes: application to the RRMs, the most common RNA recognition motifs
M Krepl, A Cléry, M Blatter, FHT Allain, J Sponer
Nucleic acids research 44 (13), 6452-6470, 2016
522016
Automated and assisted RNA resonance assignment using NMR chemical shift statistics
T Aeschbacher, E Schmidt, M Blatter, C Maris, O Duss, FHT Allain, ...
Nucleic acids research 41 (18), e172-e172, 2013
502013
Rational Design of Membrane‐Pore‐Forming Peptides
M Pillong, JA Hiss, P Schneider, YC Lin, G Posselt, B Pfeiffer, M Blatter, ...
Small 13 (40), 1701316, 2017
342017
Pharmacokinetic Studies around the Mono‐and Difunctionalization of a Bioavailable Cyclic Decapeptide Scaffold
M Fouché, M Schäfer, M Blatter, J Berghausen, S Desrayaud, HJ Roth
ChemMedChem 11 (10), 1060-1068, 2016
302016
Structural study of the Fox-1 RRM protein hydration reveals a role for key water molecules in RRM-RNA recognition
M Krepl, M Blatter, A Cléry, FF Damberger, FHT Allain, J Sponer
Nucleic Acids Research 45 (13), 8046-8063, 2017
292017
The signature of the five-stranded vRRM fold defined by functional, structural and computational analysis of the hnRNP L protein
M Blatter, S Dunin-Horkawicz, I Grishina, C Maris, S Thore, T Maier, ...
Journal of molecular biology 427 (19), 3001-3022, 2015
282015
Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood
J Quancard, O Simic, C Pissot Soldermann, R Aichholz, M Blatter, ...
Journal of Medicinal Chemistry 63 (23), 14594-14608, 2020
202020
Peptide–membrane interaction between targeting and lysis
K Stutz, AT Müller, JA Hiss, P Schneider, M Blatter, B Pfeiffer, G Posselt, ...
ACS chemical biology 12 (9), 2254-2259, 2017
142017
Paradoxical increase of permeability and lipophilicity with the increasing topological polar surface area within a series of PRMT5 inhibitors
U Argikar, M Blatter, D Bednarczyk, Z Chen, YS Cho, M Doré, ...
Journal of medicinal chemistry 65 (18), 12386-12402, 2022
132022
Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)
A Joshi, V Esteve, AN Buckroyd, M Blatter, FHT Allain, S Curry
PeerJ 2, e305, 2014
102014
Morphing of amphipathic helices to explore the activity and selectivity of membranolytic antimicrobial peptides
AT Müller, G Posselt, G Gabernet, C Neuhaus, S Bachler, M Blatter, ...
Biochemistry 59 (39), 3772-3781, 2020
62020
RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription
M Blatter, C Meylan, A Cléry, R Giambruno, Y Nikolaev, M Heidecker, ...
Science advances 9 (16), eadf5330, 2023
32023
Peptides: Rational Design of Membrane‐Pore‐Forming Peptides (Small 40/2017)
M Pillong, JA Hiss, P Schneider, YC Lin, G Posselt, B Pfeiffer, M Blatter, ...
Small 13 (40), 2017
2017
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