| Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance J König, AT Nies, Y Cui, I Leier, D Keppler Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 377-394, 1999 | 988 | 1999 |
| A novel human organic anion transporting polypeptide localized to the basolateral hepatocyte membrane J König, Y Cui, AT Nies, D Keppler American Journal of Physiology-Gastrointestinal and Liver Physiology 278 (1 …, 2000 | 763 | 2000 |
| Localization and genomic organization of a new hepatocellular organic anion transporting polypeptide J König, Y Cui, AT Nies, D Keppler Journal of Biological Chemistry 275 (30), 23161-23168, 2000 | 641 | 2000 |
| Expression and immunolocalization of the multidrug resistance proteins, MRP1–MRP6 (ABCC1–ABCC6), in human brain AT Nies, G Jedlitschky, J König, C Herold-Mende, HH Steiner, HP Schmitt, ... Neuroscience 129 (2), 349-360, 2004 | 472 | 2004 |
| The apical conjugate efflux pump ABCC2 (MRP2) AT Nies, D Keppler Pflügers Archiv-European Journal of Physiology 453, 643-659, 2007 | 469 | 2007 |
| Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy AT Nies, H Koepsell, K Damme, M Schwab Drug transporters, 105-167, 2011 | 452 | 2011 |
| Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane M Rius, AT Nies, J Hummel‐Eisenbeiss, G Jedlitschky, D Keppler Hepatology 38 (2), 374-384, 2003 | 443 | 2003 |
| Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver AT Nies, H Koepsell, S Winter, O Burk, K Klein, R Kerb, UM Zanger, ... Hepatology 50 (4), 1227-1240, 2009 | 439 | 2009 |
| ABCC drug efflux pumps and organic anion uptake transporters in human gliomas and the blood-tumor barrier H Bronger, J König, K Kopplow, HH Steiner, R Ahmadi, C Herold-Mende, ... Cancer research 65 (24), 11419-11428, 2005 | 370 | 2005 |
| Impact of Genetic Polymorphisms of ABCB1 (MDR1, P-Glycoprotein) on Drug Disposition and Potential Clinical Implications: Update of the Literature S Wolking, E Schaeffeler, H Lerche, M Schwab, AT Nies Clinical pharmacokinetics 54, 709-735, 2015 | 277 | 2015 |
| Expression and localization of human multidrug resistance protein (ABCC) family members in pancreatic carcinoma J König, M Hartel, AT Nies, ME Martignoni, J Guo, MW Büchler, H Friess, ... International journal of cancer 115 (3), 359-367, 2005 | 257 | 2005 |
| Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma AT Nies, J König, M Pfannschmidt, E Klar, WJ Hofmann, D Keppler International journal of cancer 94 (4), 492-499, 2001 | 229 | 2001 |
| Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects A Emami Riedmaier, P Fisel, AT Nies, E Schaeffeler, M Schwab Trends in pharmacological sciences 34 (2), 126-135, 2013 | 201 | 2013 |
| Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs) AT Nies, U Hofmann, C Resch, E Schaeffeler, M Rius, M Schwab PloS one 6 (7), e22163, 2011 | 191 | 2011 |
| Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1 AT Nies, M Niemi, O Burk, S Winter, UM Zanger, B Stieger, M Schwab, ... Genome medicine 5, 1-11, 2013 | 188 | 2013 |
| Changes in the expression and localization of hepatocellular transporters and radixin in primary biliary cirrhosis H Kojima, AT Nies, J König, W Hagmann, H Spring, M Uemura, H Fukui, ... Journal of hepatology 39 (5), 693-702, 2003 | 188 | 2003 |
| A naturally occurring mutation in the SLC21A6Gene causing impaired membrane localization of the hepatocyte uptake transporter C Michalski, Y Cui, AT Nies, AK Nuessler, P Neuhaus, UM Zanger, ... Journal of Biological Chemistry 277 (45), 43058-43063, 2002 | 174 | 2002 |
| Impaired protein maturation of the conjugate export pump multidrug resistance protein 2 as a consequence of a deletion mutation in Dubin–Johnson syndrome V Keitel, J Kartenbeck, AT Nies, H Spring, M Brom, D Keppler Hepatology 32 (6), 1317-1328, 2000 | 167 | 2000 |
| DNA methylation is associated with downregulation of the organic cation transporter OCT1 (SLC22A1) in human hepatocellular carcinoma E Schaeffeler, C Hellerbrand, AT Nies, S Winter, S Kruck, U Hofmann, ... Genome medicine 3, 1-12, 2011 | 161 | 2011 |
| Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma Y Cui, J König, AT Nies, M Pfannschmidt, M Hergt, WW Franke, W Alt, ... Laboratory investigation 83 (4), 527-538, 2003 | 150 | 2003 |
