Marcel Kool
TitelZitiert vonJahr
Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415, 2013
40032013
A family of drug transporters: the multidrug resistance-associated proteins
P Borst, R Evers, M Kool, J Wijnholds
Journal of the National Cancer Institute 92 (16), 1295-1302, 2000
19192000
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226, 2012
13602012
Molecular subgroups of medulloblastoma: the current consensus
MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ...
Acta neuropathologica 123 (4), 465-472, 2012
10562012
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines
M Kool, M de Haas, GL Scheffer, RJ Scheper, MJT van Eijk, JA Juijn, ...
Cancer research 57 (16), 3537-3547, 1997
10431997
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
10232012
The multidrug resistance protein family
P Borst, R Evers, M Kool, J Wijnholds
Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999
7771999
MRP3, an organic anion transporter able to transport anti-cancer drugs
M Kool, M van der Linden, M de Haas, GL Scheffer, JML De Vree, ...
Proceedings of the National Academy of Sciences 96 (12), 6914-6919, 1999
7051999
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ...
PloS one 3 (8), e3088, 2008
6202008
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ...
Acta neuropathologica 123 (4), 473-484, 2012
6172012
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100, 2012
6132012
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome
CC Paulusma, M Kool, PJ Bosma, GL Scheffer, F ter Borg, RJ Scheper, ...
Hepatology 25 (6), 1539-1542, 1997
5951997
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1-2), 59-71, 2012
5582012
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ...
Nature 488 (7409), 49, 2012
5372012
Mutations in ABCC6 cause pseudoxanthoma elasticum
AAB Bergen, AS Plomp, EJ Schuurman, S Terry, M Breuning, ...
Nature genetics 25 (2), 228, 2000
5372000
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of Clinical Oncology 29 (11), 1424, 2011
5302011
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2
JH Hooijberg, HJ Broxterman, M Kool, YG Assaraf, GJ Peters, ...
Cancer Research 59 (11), 2532-2535, 1999
5301999
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.
R Evers, M Kool, L van Deemter, H Janssen, J Calafat, LC Oomen, ...
The Journal of clinical investigation 101 (7), 1310-1319, 1998
5051998
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124 (3), 439-447, 2012
4602012
Medulloblastomics: the end of the beginning
PA Northcott, DTW Jones, M Kool, GW Robinson, RJ Gilbertson, YJ Cho, ...
Nature Reviews Cancer 12 (12), 818, 2012
4362012
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