| Signatures of mutational processes in human cancer LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ... Nature 500 (7463), 415, 2013 | 3496 | 2013 |
| A family of drug transporters: the multidrug resistance-associated proteins P Borst, R Evers, M Kool, J Wijnholds Journal of the National Cancer Institute 92 (16), 1295-1302, 2000 | 1933 | 2000 |
| Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226, 2012 | 1287 | 2012 |
| Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines M Kool, M de Haas, GL Scheffer, RJ Scheper, MJT van Eijk, JA Juijn, ... Cancer research 57 (16), 3537-3547, 1997 | 1054 | 1997 |
| Molecular subgroups of medulloblastoma: the current consensus MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ... Acta neuropathologica 123 (4), 465-472, 2012 | 990 | 2012 |
| Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 946 | 2012 |
| The multidrug resistance protein family P Borst, R Evers, M Kool, J Wijnholds Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999 | 782 | 1999 |
| MRP3, an organic anion transporter able to transport anti-cancer drugs M Kool, M Van Der Linden, M de Haas, GL Scheffer, JML De Vree, ... Proceedings of the National Academy of Sciences 96 (12), 6914-6919, 1999 | 714 | 1999 |
| A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin‐Johnson syndrome CC Paulusma, M Kool, PJ Bosma, GL Scheffer, F ter Borg, RJ Scheper, ... Hepatology 25 (6), 1539-1542, 1997 | 603 | 1997 |
| Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100, 2012 | 601 | 2012 |
| Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ... PloS one 3 (8), e3088, 2008 | 600 | 2008 |
| Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123 (4), 473-484, 2012 | 587 | 2012 |
| Mutations in ABCC6 cause pseudoxanthoma elasticum AAB Bergen, AS Plomp, EJ Schuurman, S Terry, M Breuning, ... Nature genetics 25 (2), 228, 2000 | 534 | 2000 |
| Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ... Cell 148 (1), 59-71, 2012 | 533 | 2012 |
| Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2 JH Hooijberg, HJ Broxterman, M Kool, YG Assaraf, GJ Peters, ... Cancer Research 59 (11), 2532-2535, 1999 | 529 | 1999 |
| Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ... Journal of Clinical Oncology 29 (11), 1424, 2011 | 515 | 2011 |
| Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, AS Morrissy, T Zichner, ... Nature 488 (7409), 49, 2012 | 510 | 2012 |
| Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA. R Evers, M Kool, L van Deemter, H Janssen, J Calafat, LCJM Oomen, ... The Journal of clinical investigation 101 (7), 1310-1319, 1998 | 502 | 1998 |
| K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ... Acta neuropathologica 124 (3), 439-447, 2012 | 424 | 2012 |
| Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells M Kool, M Van Der Linden, M De Haas, F Baas, P Borst Cancer Research 59 (1), 175-182, 1999 | 418 | 1999 |
Stefan M. PfisterProfessor of Pediatrics, Hopp-Children´s Cancer Center at NCT Heidelberg, GermanBestätigte E-Mail-Adresse bei kitz-heidelberg.de