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Marcel Kool
Marcel Kool
PI, Hopp Children's Cancer Center Heidelberg & Princess Maxima Center Pediatric Oncology Utrecht
Bestätigte E-Mail-Adresse bei dkfz.de
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Signatures of mutational processes in human cancer
LB Alexandrov, S Nik-Zainal, DC Wedge, SAJR Aparicio, S Behjati, ...
Nature 500 (7463), 415-421, 2013
85662013
Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma
J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ...
Nature 482 (7384), 226-231, 2012
23252012
A family of drug transporters: the multidrug resistance-associated proteins
P Borst, R Evers, M Kool, J Wijnholds
Journal of the National Cancer Institute 92 (16), 1295-1302, 2000
22272000
Molecular subgroups of medulloblastoma: the current consensus
MD Taylor, PA Northcott, A Korshunov, M Remke, YJ Cho, SC Clifford, ...
Acta neuropathologica 123, 465-472, 2012
17942012
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ...
Cancer cell 22 (4), 425-437, 2012
17542012
DNA methylation-based classification of central nervous system tumours
D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ...
Nature 555 (7697), 469-474, 2018
16352018
Analysis of Expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, Homologues of the Multidrug Resistance-associated Protein Gene (MRP1), in Human …
M Kool, M de Haas, GL Scheffer, RJ Scheper, MJT van Eijk, JA Juijn, ...
Cancer research 57 (16), 3537-3547, 1997
11471997
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
10532020
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ...
Acta neuropathologica 123, 473-484, 2012
10152012
The landscape of genomic alterations across childhood cancers
SN Gröbner, BC Worst, J Weischenfeldt, I Buchhalter, K Kleinheinz, ...
Nature 555 (7696), 321-327, 2018
9442018
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups
KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ...
Cancer cell 27 (5), 728-743, 2015
8982015
Dissecting the genomic complexity underlying medulloblastoma
DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ...
Nature 488 (7409), 100-105, 2012
8782012
The multidrug resistance protein family
P Borst, R Evers, M Kool, J Wijnholds
Biochimica et Biophysica Acta (BBA)-Biomembranes 1461 (2), 347-357, 1999
8561999
Subgroup-specific structural variation across 1,000 medulloblastoma genomes
PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ...
Nature 488 (7409), 49-56, 2012
8502012
K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas
DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ...
Acta neuropathologica 124, 439-447, 2012
8402012
Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
T Rausch, DTW Jones, M Zapatka, AM Stütz, T Zichner, J Weischenfeldt, ...
Cell 148 (1-2), 59-71, 2012
8282012
MRP3, an organic anion transporter able to transport anti-cancer drugs
M Kool, M Van Der Linden, M de Haas, GL Scheffer, JML De Vree, ...
Proceedings of the National Academy of Sciences 96 (12), 6914-6919, 1999
7891999
Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
M Kool, J Koster, J Bunt, NE Hasselt, A Lakeman, P Van Sluis, D Troost, ...
PloS one 3 (8), e3088, 2008
7772008
Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
YJ Cho, A Tsherniak, P Tamayo, S Santagata, A Ligon, H Greulich, ...
Journal of clinical oncology 29 (11), 1424, 2011
7532011
The whole-genome landscape of medulloblastoma subtypes
PA Northcott, I Buchhalter, AS Morrissy, V Hovestadt, J Weischenfeldt, ...
Nature 547 (7663), 311-317, 2017
7442017
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