Leona D. Samson
Leona D. Samson
Professor Emerita, Biological Engineering, Biology MIT
Verified email at
Cited by
Cited by
The Lancet Commission on pollution and health
PJ Landrigan, R Fuller, NJR Acosta, O Adeyi, R Arnold, AB Baldé, ...
The lancet 391 (10119), 462-512, 2018
Balancing repair and tolerance of DNA damage caused by alkylating agents
D Fu, JA Calvo, LD Samson
Nature Reviews Cancer 12 (2), 104-120, 2012
A new pathway for DNA repair in Escherichia coli
L Samson, J Cairns
Nature 267 (5608), 281-283, 1977
Systematic discovery of in vivo phosphorylation networks
R Linding, LJ Jensen, GJ Ostheimer, MATM van Vugt, C Jřrgensen, ...
Cell 129 (7), 1415-1426, 2007
DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice
LB Meira, JM Bugni, SL Green, CW Lee, B Pang, D Borenshtein, ...
The Journal of clinical investigation 118 (7), 2516-2525, 2008
Standardizing global gene expression analysis between laboratories and across platforms
Toxicogenomics Research Consortium Weis BK weis@ niehs. nih. gov 1 b
Nature methods 2 (5), 351-356, 2005
Global response of Saccharomyces cerevisiae to an alkylating agent
SA Jelinsky, LD Samson
Proceedings of the National Academy of Sciences 96 (4), 1486-1491, 1999
The human gut bacterial genotoxin colibactin alkylates DNA
MR Wilson, Y Jiang, PW Villalta, A Stornetta, PD Boudreau, A Carrá, ...
Science 363 (6428), eaar7785, 2019
Base excision repair in yeast and mammals
A Memisoglu, L Samson
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 451 (1 …, 2000
Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes
SA Jelinsky, P Estep, GM Church, LD Samson
Molecular and cellular biology 20 (21), 8157-8167, 2000
ARID1A deficiency promotes mutability and potentiates therapeutic antitumor immunity unleashed by immune checkpoint blockade
J Shen, Z Ju, W Zhao, L Wang, Y Peng, Z Ge, ZD Nagel, J Zou, C Wang, ...
Nature medicine 24 (5), 556-562, 2018
Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents
MJ Hickman, LD Samson
Proceedings of the National Academy of Sciences 96 (19), 10764-10769, 1999
A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction
A Sivaraman, JK Leach, S Townsend, T Iida, BJ Hogan, DB Stolz, R Fry, ...
Current drug metabolism 6 (6), 569-591, 2005
Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision
AY Lau, OD Schärer, L Samson, GL Verdine, T Ellenberger
Cell 95 (2), 249-258, 1998
A systems approach to mapping DNA damage response pathways
CT Workman, HC Mak, S McCuine, JB Tagne, M Agarwal, O Ozier, ...
Science 312 (5776), 1054-1059, 2006
Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase
BP Engelward, G Weeda, MD Wyatt, JLM Broekhof, J De Wit, I Donker, ...
Proceedings of the National Academy of Sciences 94 (24), 13087-13092, 1997
Evidence for an adaptive DNA repair pathway in CHO and human skin fibroblast cell lines
L Samson, JL Schwartz
Nature 287 (5785), 861-863, 1980
Activation of inflammation/NF-κB signaling in infants born to arsenic-exposed mothers
RC Fry, P Navasumrit, C Valiathan, JP Svensson, BJ Hogan, M Luo, ...
PLoS genetics 3 (11), e207, 2007
Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG
AY Lau, MD Wyatt, BJ Glassner, LD Samson, T Ellenberger
Proceedings of the National Academy of Sciences 97 (25), 13573-13578, 2000
An adaptive response of E. coli to low levels of alkylating agent: comparison with previously characterised DNA repair pathways
P Jeggo, M Defais, L Samson, P Schendel
Molecular and General Genetics MGG 157 (1), 1-9, 1977
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