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Senthil Kumar Thangaraj
Senthil Kumar Thangaraj
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How specific are the conformation-specific α-synuclein antibodies? Characterization and validation of 16 α-synuclein conformation-specific antibodies using well-characterized …
ST Kumar, S Jagannath, C Francois, H Vanderstichele, E Stoops, ...
Neurobiology of Disease 146, 105086, 2020
1142020
Liquefaction of semen generates and later degrades a conserved semenogelin peptide that enhances HIV infection
NR Roan, H Liu, SM Usmani, J Neidleman, JA Müller, A Avila-Herrera, ...
Journal of virology 88 (13), 7221-7234, 2014
702014
Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM
U Cendrowska, PJ Silva, N Ait-Bouziad, M Müller, ZP Guven, S Vieweg, ...
Proceedings of the National Academy of Sciences 117 (12), 6866-6874, 2020
532020
A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving …
ST Kumar, S Donzelli, A Chiki, MMK Syed, HA Lashuel
Journal of Neurochemistry 153 (1), 103-119, 2020
522020
A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: towards improving …
ST Kumar, S Donzelli, A Chiki, K Syed Muhammed Muazzam, HA Lashuel
bioRxiv, 772160, 2019
522019
Pattern recognition with a fibril-specific antibody fragment reveals the surface variability of natural amyloid fibrils
C Haupt, M Bereza, ST Kumar, B Kieninger, I Morgado, P Hortschansky, ...
Journal of molecular biology 408 (3), 529-540, 2011
492011
Chronic corticosterone aggravates behavioral and neuronal symptomatology in a mouse model of alpha-synuclein pathology
J Burtscher, JC Copin, J Rodrigues, ST Kumar, A Chiki, IG de Suduiraut, ...
Neurobiology of aging 83, 11-20, 2019
392019
Amyloid fibril recognition with the conformational B10 antibody fragment depends on electrostatic interactions
C Haupt, I Morgado, ST Kumar, C Parthier, M Bereza, P Hortschansky, ...
Journal of molecular biology 405 (2), 341-348, 2011
392011
Structural characterization of amyloid fibrils from the human parathyroid hormone
M Gopalswamy, A Kumar, J Adler, M Baumann, M Henze, ST Kumar, ...
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (4), 249-257, 2015
382015
A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
ST Kumar, AL Mahul-Mellier, RN Hegde, G Rivière, R Moons, ...
Science Advances 8 (17), eabn0044, 2022
312022
Structure and Biomedical Applications of Amyloid Oligomer Nanoparticles
ST Kumar, J Meinhardt, AK Fuchs, T Aumüller, J Leppert, B Büchele, ...
ACS nano 8 (11), 11042-11052, 2014
302014
Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage
ST Kumar, S Nazarov, S Porta, N Maharjan, U Cendrowska, M Kabani, ...
Nature Neuroscience 26 (6), 983-996, 2023
202023
Solvent Removal Induces a Reversible β-to-α Switch in Oligomeric Aβ Peptide
ST Kumar, J Leppert, P Bellstedt, C Wiedemann, M Fändrich, M Görlach
Journal of molecular biology 428 (2), 268-273, 2016
182016
Disulfide conformation and design at helix N‐termini
S Indu, ST Kumar, S Thakurela, M Gupta, RM Bhaskara, C Ramakrishnan, ...
Proteins: Structure, Function, and Bioinformatics 78 (5), 1228-1242, 2010
172010
Artificial intelligence–coupled plasmonic infrared sensor for detection of structural protein biomarkers in neurodegenerative diseases
D Kavungal, P Magalhães, ST Kumar, R Kolla, HA Lashuel, H Altug
Science Advances 9 (28), eadg9644, 2023
152023
Molecular architecture of Aβ fibrils grown in cerebrospinal fluid solution and in a cell culture model of Aβ plaque formation
M Garvey, M Baumann, M Wulff, ST Kumar, D Markx, I Morgado, ...
Amyloid 23 (2), 76-85, 2016
82016
Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
MF Altay, ST Kumar, J Burtscher, S Jagannath, C Strand, Y Miki, ...
npj Parkinson's Disease 9 (1), 161, 2023
62023
Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
S Donzelli, SA OSullivan, AL Mahul-Mellier, A Ulusoy, G Fusco, ST Kumar, ...
BioRxiv, 2023.03. 24.534149, 2023
42023
Chronic corticosterone enhancement aggravates alpha-synuclein brain spreading pathology and substantia nigra neurodegeneration in mice
J Burtscher, JC Copin, J Rodrigues, SK Thangaraj, A Chiki, ...
bioRxiv, 469999, 2018
12018
Deep learning augmented nanoplasmonic infrared sensor for structural protein biomarker-based detection of neurodegenerative diseases
D Kavungal, P Magalhães, ST Kumar, R Kolla, H Lashuel, H Altug
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XXI …, 2024
2024
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