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Qian Wang
Qian Wang
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Complement C3aR inactivation attenuates tau pathology and reverses an immune network deregulated in tauopathy models and Alzheimer’s disease
A Litvinchuk, YW Wan, DB Swartzlander, F Chen, A Cole, NE Propson, ...
Neuron 100 (6), 1337-1353. e5, 2018
3422018
Microglia clear neuron-released α-synuclein via selective autophagy and prevent neurodegeneration
I Choi, Y Zhang, SP Seegobin, M Pruvost, Q Wang, K Purtell, B Zhang, ...
Nature communications 11 (1), 1386, 2020
3312020
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease
M Wang, ND Beckmann, P Roussos, E Wang, X Zhou, Q Wang, C Ming, ...
Scientific data 5 (1), 1-16, 2018
3102018
Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets
RA Neff, M Wang, S Vatansever, L Guo, C Ming, Q Wang, E Wang, ...
Science advances 7 (2), eabb5398, 2021
1622021
ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway
Z Deng, J Lim, Q Wang, K Purtell, S Wu, GM Palomo, H Tan, G Manfredi, ...
Autophagy 16 (5), 917-931, 2020
1342020
Parkinson's disease-associated LRRK2 hyperactive kinase mutant disrupts synaptic vesicle trafficking in ventral midbrain neurons
PY Pan, X Li, J Wang, J Powell, Q Wang, Y Zhang, Z Chen, B Wicinski, ...
Journal of Neuroscience 37 (47), 11366-11376, 2017
1282017
Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease
M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ...
Neuron 109 (2), 257-272. e14, 2021
1142021
The landscape of multiscale transcriptomic networks and key regulators in Parkinson’s disease
Q Wang, Y Zhang, M Wang, WM Song, Q Shen, A McKenzie, I Choi, ...
Nature communications 10 (1), 5234, 2019
952019
Integrative metabolomics‐genomics approach reveals key metabolic pathways and regulators of Alzheimer's disease
E Horgusluoglu, R Neff, WM Song, M Wang, Q Wang, M Arnold, ...
Alzheimer's & Dementia 18 (6), 1260-1278, 2022
692022
Autophagy protein NRBF2 has reduced expression in Alzheimer’s brains and modulates memory and amyloid-beta homeostasis in mice
V Lachance, Q Wang, E Sweet, I Choi, CZ Cai, XX Zhuang, Y Zhang, ...
Molecular neurodegeneration 14, 1-13, 2019
552019
Guidelines for bioinformatics of single-cell sequencing data analysis in Alzheimer’s disease: review, recommendation, implementation and application
M Wang, W Song, C Ming, Q Wang, X Zhou, P Xu, A Krek, Y Yoon, L Ho, ...
Molecular neurodegeneration 17 (1), 17, 2022
452022
The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
P Xu, M Wang, W Song, Q Wang, GC Yuan, PH Sudmant, H Zare, Z Tu, ...
Molecular Neurodegeneration 17, 1-20, 2022
422022
Synj1 haploinsufficiency causes dopamine neuron vulnerability and alpha-synuclein accumulation in mice
PY Pan, P Sheehan, Q Wang, X Zhu, Y Zhang, I Choi, X Li, J Saenz, J Zhu, ...
Human molecular genetics 29 (14), 2300-2312, 2020
342020
The hippocampal proteomic analysis of senescence-accelerated mouse: implications of Uchl3 and mitofilin in cognitive disorder and mitochondria dysfunction in SAMP8
Q Wang, Y Liu, X Zou, Q Wang, M An, X Guan, J He, Y Tong, J Ji
Neurochemical Research 33, 1776-1782, 2008
312008
Growth differentiation factor 9 (GDF9) forms an incoherent feed-forward loop modulating follicle-stimulating hormone β-subunit (FSHβ) gene expression
SG Choi, Q Wang, J Jia, H Pincas, JL Turgeon, SC Sealfon
Journal of Biological Chemistry 289 (23), 16164-16175, 2014
262014
Outside the box signaling: secreted factors modulate GnRH receptor-mediated gonadotropin regulation
H Pincas, SG Choi, Q Wang, J Jia, JL Turgeon, SC Sealfon
Molecular and cellular endocrinology 385 (1-2), 56-61, 2014
232014
Sex‐specific peripheral and central responses to stress‐induced depression and treatment in a mouse model
KK Deonaraine, Q Wang, H Cheng, KL Chan, HY Lin, K Liu, LF Parise, ...
Journal of neuroscience research 98 (12), 2541-2553, 2020
182020
β-Catenin Regulates GnRH-Induced FSHβ Gene Expression
Q Wang, M Chikina, E Zaslavsky, H Pincas, SC Sealfon
Molecular Endocrinology 27 (2), 224-237, 2013
182013
Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression
Q Wang, MD Chikina, H Pincas, SC Sealfon
Molecular and Cellular Biology 34 (10), 1747-1756, 2014
152014
Systems modeling of white matter microstructural abnormalities in Alzheimer's disease
E Horgusluoglu-Moloch, G Xiao, M Wang, Q Wang, X Zhou, K Nho, ...
NeuroImage: Clinical 26, 102203, 2020
132020
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