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John C. Castle
John C. Castle
Chief Data Scientist, Monte Rosa Therapeutics
Verified email at monterosatx.com - Homepage
Title
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Cited by
Year
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
LP Lim, NC Lau, P Garrett-Engele, A Grimson, JM Schelter, J Castle, ...
Nature 433 (7027), 769-773, 2005
57902005
Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays
JM Johnson, J Castle, P Garrett-Engele, Z Kan, PM Loerch, CD Armour, ...
Science 302 (5653), 2141-2144, 2003
17912003
An integrative genomics approach to infer causal associations between gene expression and disease
EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ...
Nature genetics 37 (7), 710-717, 2005
11712005
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
S Kreiter, M Vormehr, N Van de Roemer, M Diken, M Löwer, J Diekmann, ...
Nature 520 (7549), 692-696, 2015
10802015
Genome-scale RNAi screen for host factors required for HIV replication
H Zhou, M Xu, Q Huang, AT Gates, XD Zhang, JC Castle, E Stec, M Ferrer, ...
Cell host & microbe 4 (5), 495-504, 2008
8942008
Exploiting the Mutanome for Tumor VaccinationB16 Melanoma T-cell–Druggable Mutanome
JC Castle, S Kreiter, J Diekmann, M Löwer, N Van de Roemer, J de Graaf, ...
Cancer research 72 (5), 1081-1091, 2012
8342012
Experimental annotation of the human genome using microarray technology
DD Shoemaker, EE Schadt, CD Armour, YD He, P Garrett-Engele, ...
Nature 409 (6822), 922-927, 2001
6072001
Actively personalized vaccination trial for newly diagnosed glioblastoma
N Hilf, S Kuttruff-Coqui, K Frenzel, V Bukur, S Stevanović, ...
Nature 565 (7738), 240-245, 2019
5822019
Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2
JI Young, EP Hong, JC Castle, J Crespo-Barreto, AB Bowman, MF Rose, ...
Proceedings of the national academy of sciences 102 (49), 17551-17558, 2005
5342005
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
A Kalsotra, X Xiao, AJ Ward, JC Castle, JM Johnson, CB Burge, ...
Proceedings of the National Academy of Sciences 105 (51), 20333-20338, 2008
5082008
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines
JC Castle, C Zhang, JK Shah, AV Kulkarni, A Kalsotra, TA Cooper, ...
Nature genetics 40 (12), 1416-1425, 2008
3482008
Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2
C Zhang, Z Zhang, J Castle, S Sun, J Johnson, AR Krainer, MQ Zhang
Genes & development 22 (18), 2550-2563, 2008
3192008
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma
JC Castle, M Loewer, S Boegel, J de Graaf, C Bender, AD Tadmor, ...
BMC genomics 15 (1), 1-12, 2014
3172014
Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: a resource for investigations into drug disposition
K Bleasby, JC Castle, CJ Roberts, C Cheng, WJ Bailey, JF Sina, ...
Xenobiotica 36 (10-11), 963-988, 2006
3002006
Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling
X Peng, L Gralinski, CD Armour, MT Ferris, MJ Thomas, S Proll, ...
MBio 1 (5), e00206-10, 2010
2522010
HLA typing from RNA-Seq sequence reads
S Boegel, M Löwer, M Schäfer, T Bukur, J De Graaf, V Boisguérin, ...
Genome medicine 4, 1-12, 2013
2442013
Digital transcriptome profiling using selective hexamer priming for cDNA synthesis
CD Armour, JC Castle, R Chen, T Babak, P Loerch, S Jackson, JK Shah, ...
Nature methods 6 (9), 647-649, 2009
2282009
Comparative expression pathway analysis of human and canine mammary tumors
P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni, J Castle, ...
BMC genomics 10 (1), 1-20, 2009
1872009
RNA-Seq Atlas—a reference database for gene expression profiling in normal tissue by next-generation sequencing
M Krupp, JU Marquardt, U Sahin, PR Galle, J Castle, A Teufel
Bioinformatics 28 (8), 1184-1185, 2012
1802012
Definition, conservation and epigenetics of housekeeping and tissue-enriched genes
X She, CA Rohl, JC Castle, AV Kulkarni, JM Johnson, R Chen
BMC genomics 10, 1-12, 2009
1742009
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