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Charles Ng
Charles Ng
Weill Cornell Pathology and Memorial Sloan Kettering Cancer Center
Bestätigte E-Mail-Adresse bei mskcc.org
Titel
Zitiert von
Zitiert von
Jahr
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF (V600E)
PI Poulikakos, Y Persaud, M Janakiraman, X Kong, C Ng, G Moriceau, ...
Nature 480 (7377), 387-390, 2011
16292011
Melanoma whole-exome sequencing identifies V600EB-RAF amplification-mediated acquired B-RAF inhibitor resistance
H Shi, G Moriceau, X Kong, MK Lee, H Lee, RC Koya, C Ng, T Chodon, ...
Nature communications 3 (1), 724, 2012
8152012
Focused specificity of intestinal TH17 cells towards commensal bacterial antigens
Y Yang, MB Torchinsky, M Gobert, H Xiong, M Xu, JL Linehan, F Alonzo, ...
Nature 510 (7503), 152-156, 2014
5472014
Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway
M Atefi, E von Euw, N Attar, C Ng, C Chu, D Guo, R Nazarian, ...
PloS one 6 (12), e28973, 2011
2762011
Adoptive transfer of MART-1 T-cell receptor transgenic lymphocytes and dendritic cell vaccination in patients with metastatic melanoma
T Chodon, B Comin-Anduix, B Chmielowski, RC Koya, Z Wu, M Auerbach, ...
Clinical Cancer Research 20 (9), 2457-2465, 2014
2632014
Polymer nanofiber‐embedded microchips for detection, isolation, and molecular analysis of single circulating melanoma cells
S Hou, L Zhao, Q Shen, J Yu, C Ng, X Kong, D Wu, M Song, X Shi, X Xu, ...
Angewandte Chemie 125 (12), 3463-3467, 2013
2452013
BRAF L597 Mutations in Melanoma Are Associated with Sensitivity to MEK Inhibitors
KB Dahlman, J Xia, K Hutchinson, C Ng, D Hucks, P Jia, M Atefi, Z Su, ...
Cancer discovery 2 (9), 791-797, 2012
2342012
A novel AKT1 mutant amplifies an adaptive melanoma response to BRAF inhibition
H Shi, A Hong, X Kong, RC Koya, C Song, G Moriceau, W Hugo, CC Yu, ...
Cancer discovery 4 (1), 69-79, 2014
1832014
Multifunctional T-cell analyses to study response and progression in adoptive cell transfer immunotherapy
C Ma, AF Cheung, T Chodon, RC Koya, Z Wu, C Ng, E Avramis, ...
Cancer discovery 3 (4), 418-429, 2013
1502013
Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutations
F Niehr, E von Euw, N Attar, D Guo, D Matsunaga, H Sazegar, C Ng, ...
Journal of translational medicine 9, 1-13, 2011
1142011
Antitumor effects of the investigational selective MEK inhibitor TAK733 against cutaneous and uveal melanoma cell lines
E von Euw, M Atefi, N Attar, C Chu, S Zachariah, BL Burgess, S Mok, C Ng, ...
Molecular cancer 11, 1-9, 2012
902012
Niche-selective inhibition of pathogenic Th17 cells by targeting metabolic redundancy
L Wu, KER Hollinshead, Y Hao, C Au, L Kroehling, C Ng, WY Lin, D Li, ...
Cell 182 (3), 641-654. e20, 2020
852020
Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma
M Atefi, B Titz, E Avramis, C Ng, DJL Wong, A Lassen, M Cerniglia, ...
Molecular cancer 14, 1-12, 2015
632015
COX-2 inhibition prevents the appearance of cutaneous squamous cell carcinomas accelerated by BRAF inhibitors
H Escuin-Ordinas, M Atefi, Y Fu, A Cass, C Ng, RR Huang, S Yashar, ...
Molecular oncology 8 (2), 250-260, 2014
532014
Heritable gene regulation in the CD4: CD8 T cell lineage choice
PDA Issuree, CP Ng, DR Littman
Frontiers in immunology 8, 250073, 2017
392017
SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
W Gu, H Wang, X Huang, J Kraiczy, PNP Singh, C Ng, S Dagdeviren, ...
Cell Stem Cell 29 (1), 101-115. e10, 2022
372022
Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes
T Sano, T Kageyama, V Fang, R Kedmi, CS Martinez, J Talbot, A Chen, ...
Cell reports 36 (8), 2021
272021
The histone chaperone CAF-1 cooperates with the DNA methyltransferases to maintain Cd4 silencing in cytotoxic T cells
C Ng, M Aichinger, T Nguyen, C Au, T Najar, L Wu, KR Mesa, W Liao, ...
Genes & Development 33 (11-12), 669-683, 2019
272019
Lactate activates the mitochondrial electron transport chain independently of its metabolism
X Cai, CP Ng, O Jones, TS Fung, KW Ryu, D Li, CB Thompson
Molecular cell 83 (21), 3904-3920. e7, 2023
222023
Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell–derived cytokines
S Schwörer, FV Cimino, M Ros, KM Tsanov, C Ng, SW Lowe, ...
Cancer research 83 (10), 1596-1610, 2023
202023
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