| Synthesis and SAR of a New Series of COX-2-Selective Inhibitors: Pyrazolo[1,5-a]pyrimidines C Almansa, AF de Arriba, FL Cavalcanti, LA Gómez, A Miralles, M Merlos, ... Journal of medicinal chemistry 44 (3), 350-361, 2001 | 233 | 2001 |
| Synthesis and structure− activity relationship of a new series of COX-2 selective inhibitors: 1, 5-diarylimidazoles C Almansa, J Alfón, AF de Arriba, FL Cavalcanti, I Escamilla, LA Gómez, ... Journal of medicinal chemistry 46 (16), 3463-3475, 2003 | 178 | 2003 |
| Synthesis and Biological Evaluation of the 1-Arylpyrazole Class of σ1 Receptor Antagonists: Identification of 4-{2-[5-Methyl-1-(naphthalen-2-yl)-1H-pyrazol-3-yloxy … JL Díaz, R Cuberes, J Berrocal, M Contijoch, U Christmann, A Fernández, ... Journal of medicinal chemistry 55 (19), 8211-8224, 2012 | 141 | 2012 |
| Co-crystal of Tramadol Hydrochloride–Celecoxib (ctc): A Novel API–API Co-crystal for the Treatment of Pain C Almansa, R Merce, N Tesson, J Farran, J Tomas, CR Plata-Salaman Crystal Growth & Design 17 (4), 1884-1892, 2017 | 136 | 2017 |
| Synthesis and Structure−Activity Relationship of a New Series of Potent AT1 Selective Angiotensin II Receptor Antagonists: 5-(Biphenyl-4-ylmethyl)pyrazoles C Almansa, LA Gómez, FL Cavalcanti, AF de Arriba, J García-Rafanell, ... Journal of medicinal chemistry 40 (4), 547-558, 1997 | 112 | 1997 |
| Pyrazolopyridine derivates CA Rosales, MV Bernadó US Patent 7,468,376, 2008 | 99* | 2008 |
| Pyrazolopyridine Derivates CA Rosales, MV Bernadó US Patent App. 12/511,469, 2009 | 92 | 2009 |
| Theoretical studies on the inhibition mechanism of cyclooxygenase-2. Is there a unique recognition site? R Soliva, C Almansa, SG Kalko, FJ Luque, M Orozco Journal of medicinal chemistry 46 (8), 1372-1382, 2003 | 79 | 2003 |
| A potent and selective p38 inhibitor protects against bone damage in murine collagen‐induced arthritis: a comparison with neutralization of mouse TNFα K Mihara, C Almansa, RL Smeets, E Loomans, J Dulos, PMF Vink, ... British journal of pharmacology 154 (1), 153-164, 2008 | 67 | 2008 |
| In vitro pharmacological characterization of a new selective angiotensin AT1 receptor antagonist, UR-7280 AF De Arriba, LA Gómez-Casajús, F Cavalcanti, C Almansa, ... European journal of pharmacology 318 (2-3), 341-347, 1996 | 63 | 1996 |
| Synthesis and structure-activity relationships of 1-acyl-4-((2-methyl-3-pyridyl) cyanomethyl) piperazines as PAF antagonists E Carceller, M Merlos, M Giral, C Almansa, J Bartroli, J Garcia-Rafanell, ... Journal of medicinal chemistry 36 (20), 2984-2997, 1993 | 58 | 1993 |
| Investigational sigma-1 receptor antagonists for the treatment of pain JM Vela, M Merlos, C Almansa Expert Opinion on Investigational Drugs 24 (7), 883-896, 2015 | 54 | 2015 |
| Selective sigma-1 receptor antagonists for the treatment of pain C Almansa, JM Vela Future medicinal chemistry 6 (10), 1179-1199, 2014 | 54 | 2014 |
| Diphenylpropionic acids as new AT1 selective angiotensin II antagonists C Almansa, LA Gómez, FL Cavalcanti, AF de Arriba, R Rodríguez, ... Journal of medicinal chemistry 39 (11), 2197-2206, 1996 | 52 | 1996 |
| Synthesis and Biological Evaluation of a New Series of Hexahydro-2H-pyrano[3,2-c]quinolines as Novel Selective σ1 Receptor Ligands JL Díaz, U Christmann, A Fernandez, M Luengo, M Bordas, R Enrech, ... Journal of Medicinal Chemistry 56 (9), 3656-3665, 2013 | 49 | 2013 |
| New water-soluble sulfonylphosphoramidic acid derivatives of the COX-2 selective inhibitor cimicoxib. A novel approach to sulfonamide prodrugs C Almansa, J Bartrolí, J Belloc, FL Cavalcanti, R Ferrando, LA Gómez, ... Journal of medicinal chemistry 47 (22), 5579-5582, 2004 | 46 | 2004 |
| [(3-Pyridylalkyl) piperidylidene] benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine E Carceller, M Merlos, M Giral, D Balsa, C Almansa, J Bartroli, ... Journal of medicinal chemistry 37 (17), 2697-2703, 1994 | 44 | 1994 |
| 8-chloro-11-[1-[(5-methyl-3-pyridyl) methyl]-4-piperidyliden]-6, 11-dihydro-5H-benzo [5, 6] cyclohepta [1,] pyridine E Carceller, N Recasens, C Almansa, J Bartroli, M Merlos, M Giral, ... US Patent 5,407,941, 1995 | 40 | 1995 |
| Synthesis and Structure–Activity Relationship Study of a New Series of Selective σ1 Receptor Ligands for the Treatment of Pain: 4-Aminotriazoles JL Díaz, U Christmann, A Fernandez, A Torrens, A Port, R Pascual, ... Journal of medicinal chemistry 58 (5), 2441-2451, 2015 | 39 | 2015 |
| A new pharmacophore model for the design of sigma-1 ligands validated on a large experimental dataset R Pascual, C Almansa, C Plata-Salamán, JM Vela Frontiers in Pharmacology 10, 452661, 2019 | 37 | 2019 |
