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Justo Cobo Domingo
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Synthesis and antifungal activity of (Z)-5-arylidenerhodanines
M Sortino, P Delgado, S Juárez, J Quiroga, R Abonía, B Insuasty, ...
Bioorganic & Medicinal Chemistry 15 (1), 484-494, 2007
2522007
Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4, 5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor agents
B Insuasty, A Tigreros, F Orozco, J Quiroga, R Abonía, M Nogueras, ...
Bioorganic & medicinal chemistry 18 (14), 4965-4974, 2010
2432010
Synthesis of novel analogs of 2-pyrazoline obtained from [(7-chloroquinolin-4-yl) amino] chalcones and hydrazine as potential antitumor and antimalarial agents
B Insuasty, A Montoya, D Becerra, J Quiroga, R Abonia, S Robledo, ...
European journal of medicinal chemistry 67, 252-262, 2013
1622013
Synthesis of novel quinoline-2-one based chalcones of potential anti-tumor activity
R Abonia, D Insuasty, J Castillo, B Insuasty, J Quiroga, M Nogueras, ...
European journal of medicinal chemistry 57, 29-40, 2012
1522012
Regioselective synthesis of 4, 7, 8, 9-tetrahydro-2H-pyrazolo [3, 4-b] quinolin-5 (6H)-ones. Mechanism and structural analysis
J Quiroga, D Mejı́a, B Insuasty, R Abonı́a, M Nogueras, A Sánchez, ...
Tetrahedron 57 (32), 6947-6953, 2001
1182001
An efficient synthesis of new caffeine-based chalcones, pyrazolines and pyrazolo [3, 4-b][1, 4] diazepines as potential antimalarial, antitrypanosomal and antileishmanial agents
B Insuasty, J Ramírez, D Becerra, C Echeverry, J Quiroga, R Abonia, ...
European Journal of Medicinal Chemistry 93, 401-413, 2015
1152015
An efficient synthesis of pyrazolo[3,4-b]pyridine-4-spiroindolinones by a three-component reaction of 5-aminopyrazoles, isatin, and cyclic β-diketones
J Quiroga, S Portillo, A Pérez, J Gálvez, R Abonia, B Insuasty
Tetrahedron letters 52 (21), 2664-2666, 2011
1132011
Control of the reaction between 2-aminobenzothiazoles and Mannich bases. Synthesis of pyrido [2, 1-b][1, 3] benzothiazoles versus [1, 3] benzothiazolo [2, 3-b] quinazolines
J Quiroga, P Hernández, B Insuasty, R Abonía, J Cobo, A Sánchez, ...
Journal of the Chemical Society, Perkin Transactions 1, 555-559, 2002
1092002
Synthesis of novel 1, 2, 5-trisubstituted benzimidazoles as potential antitumor agents
R Abonia, E Cortés, B Insuasty, J Quiroga, M Nogueras, J Cobo
European journal of medicinal chemistry 46 (9), 4062-4070, 2011
1082011
Synthesis and structural analysis of 5‐cyanodihydropyrazolo[3,4‐b]pyridines
J Quiroga, S Cruz, B Insuasty, R Abonia, J Cobo, A Sanchez, M Nogueras, ...
Journal of Heterocyclic Chemistry 38 (1), 53-60, 2001
982001
Regioselective synthesis of fused benzopyrazolo [3, 4-b] quinolines under solvent-free conditions
J Quiroga, J Portilla, H Serrano, R Abonia, B Insuasty, M Nogueras, ...
Tetrahedron letters 48 (11), 1987-1990, 2007
842007
A regiospecific three-component one-step cyclocondensation to 6-cyano-5, 8-dihydropyrido [2, 3-d] pyrimidin-4 (3H)-ones. Using microwaves under solvent-free conditions
J Quiroga, C Cisneros, B Insuasty, R Abonı́a, M Nogueras, A Sánchez
Tetrahedron Letters 42 (33), 5625-5627, 2001
832001
Regioselective formylation of pyrazolo [3, 4-b] pyridine and pyrazolo [1, 5-a] pyrimidine systems using Vilsmeier–Haack conditions
J Quiroga, J Trilleras, B Insuasty, R Abonia, M Nogueras, J Cobo
Tetrahedron Letters 49 (17), 2689-2691, 2008
812008
Regioselective synthesis of novel substituted pyrazolo [1, 5-a] pyrimidines under solvent-free conditions
J Quiroga, J Portilla, R Abonia, B Insuasty, M Nogueras, J Cobo
Tetrahedron Letters 49 (43), 6254-6256, 2008
782008
New chalcone-sulfonamide hybrids exhibiting anticancer and antituberculosis activity
LF Castaño, V Cuartas, A Bernal, A Insuasty, J Guzman, O Vidal, V Rubio, ...
European journal of medicinal chemistry 176, 50-60, 2019
702019
Synthesis of 6‐(2‐hydroxybenzoyl)pyrazolo[1,5‐a]pyrimidines by reaction of 5‐amino‐1h‐pyrazoles and 3‐formylchromone
J Quiroga, D Mejía, B Insuasty, R Abonia, M Nogueras, A Sanchez, ...
Journal of heterocyclic chemistry 39 (1), 51-54, 2002
632002
Molecular modeling study of dihydrofolate reductase inhibitors. Molecular dynamics simulations, quantum mechanical calculations, and experimental corroboration
RD Tosso, SA Andujar, L Gutierrez, E Angelina, R Rodriguez, ...
Journal of chemical information and modeling 53 (8), 2018-2032, 2013
622013
Microwave induced synthesis of novel 8, 9-dihydro-7H-pyrimido [4, 5-b][1, 4] diazepines as potential antitumor agents
B Insuasty, F Orozco, J Quiroga, R Abonia, M Nogueras, J Cobo
European journal of medicinal chemistry 43 (9), 1955-1962, 2008
622008
N-(6-Amino-3, 4-dihydro-3-methyl-5-nitroso-4-oxopyrimidin-2-yl) derivatives of glycine, valine, serine, threonine and methionine: Interplay of molecular, molecular–electronic …
JN Low, MD López, P Arranz Mascarós, J Cobo Domingo, ML Godino, ...
Acta Crystallographica Section B: Structural Science 56 (5), 882-892, 2000
622000
Microwave-assisted synthesis of pyrazolo [3, 4-d] pyrimidines from 2-amino-4, 6-dichloropyrimidine-5-carbaldehyde under solvent-free conditions
J Quiroga, J Trilleras, B Insuasty, R Abonia, M Nogueras, A Marchal, ...
Tetrahedron Letters 49 (20), 3257-3259, 2008
612008
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