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Shawn McGuirk
Shawn McGuirk
Bestätigte E-Mail-Adresse bei mail.mcgill.ca
Titel
Zitiert von
Zitiert von
Jahr
mTOR controls mitochondrial dynamics and cell survival via MTFP1
M Morita, J Prudent, K Basu, V Goyon, S Katsumura, L Hulea, D Pearl, ...
Molecular cell 67 (6), 922-935. e5, 2017
2992017
PGC-1α promotes breast cancer metastasis and confers bioenergetic flexibility against metabolic drugs
S Andrzejewski, E Klimcakova, RM Johnson, S Tabariès, MG Annis, ...
Cell metabolism 26 (5), 778-787. e5, 2017
2332017
PGC-1α supports glutamine metabolism in breast cancer
S McGuirk, SP Gravel, G Deblois, DJ Papadopoli, B Faubert, A Wegner, ...
Cancer & metabolism 1, 1-11, 2013
1702013
Metabolic fitness and plasticity in cancer progression
S McGuirk, Y Audet-Delage, J St-Pierre
Trends in cancer 6 (1), 49-61, 2020
922020
Morphological and functional remodelling of the neuromuscular junction by skeletal muscle PGC-1α
AS Arnold, J Gill, M Christe, R Ruiz, S McGuirk, J St-Pierre, L Tabares, ...
Nature communications 5 (1), 3569, 2014
902014
Androgen-dependent repression of ERRγ reprograms metabolism in prostate cancer
É Audet-Walsh, T Yee, S McGuirk, M Vernier, C Ouellet, J St-Pierre, ...
Cancer Research 77 (2), 378-389, 2017
782017
Estrogen-related receptors are targetable ROS sensors
M Vernier, CR Dufour, S McGuirk, C Scholtes, X Li, G Bourmeau, ...
Genes & Development 34 (7-8), 544-559, 2020
722020
PGC-1α Promotes the Growth of ErbB2/Neu–Induced Mammary Tumors by Regulating Nutrient Supply
E Klimcakova, V Chénard, S McGuirk, D Germain, D Avizonis, WJ Muller, ...
Cancer research 72 (6), 1538-1546, 2012
632012
Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer
S McGuirk, Y Audet-Delage, MG Annis, Y Xue, M Vernier, K Zhao, ...
Elife 10, e65150, 2021
302021
Inhibition of DNMT1 and ERRα crosstalk suppresses breast cancer via derepression of IRF4
M Vernier, S McGuirk, CR Dufour, L Wan, E Audet-Walsh, J St-Pierre, ...
Oncogene 39 (41), 6406-6420, 2020
302020
Peroxisome proliferator‐activated receptor γ coactivator 1α regulates mitochondrial calcium homeostasis, sarcoplasmic reticulum stress, and cell death to mitigate skeletal …
JF Gill, J Delezie, G Santos, S McGuirk, S Schnyder, S Frank, M Rausch, ...
Aging Cell 18 (5), e12993, 2019
252019
Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production
DA Patten, S McGuirk, U Anilkumar, G Antoun, K Gandhi, G Parmar, ...
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1868 (1), 118854, 2021
162021
Interplay between ShcA signaling and PGC-1α triggers targetable metabolic vulnerabilities in breast cancer
YK Im, O Najyb, SP Gravel, S McGuirk, R Ahn, DZ Avizonis, V Chénard, ...
Cancer Research 78 (17), 4826-4838, 2018
142018
HSP90 inhibitors induce GPNMB cell-surface expression by modulating lysosomal positioning and sensitize breast cancer cells to glembatumumab vedotin
M Biondini, A Kiepas, L El-Houjeiri, MG Annis, BE Hsu, AM Fortier, ...
Oncogene 41 (12), 1701-1717, 2022
112022
PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation
SP Gravel, YB Khalifa, S McGuirk, C St-Louis, KM Laurin, É Lavallée, ...
Iscience 26 (4), 2023
32023
Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1
Y Audet-Delage, C St-Louis, L Minarrieta, S McGuirk, I Kurreal, MG Annis, ...
Cell Reports 42 (10), 2023
12023
The Frontiers of DNA Regulation: Developing a National Policy Framework Encouraging Transparency, Security, and Cost-efficiency of Genetic Technology and Data
S McGuirk, S Sultmanis, AR Westwood, W Kathlyn N, N Nabavi
Journal of Science Policy & Governance 16 (01), 2020
2020
PGC-1α regulates mitochondrial-sarcoplasmic reticulum (SR)-mediated calcium exchange, SR stress and cell death to mitigate skeletal muscle aging
J Gill, J Delezie, S McGuirk, S Schnyder, S Gesa, S Frank, M Rausch, ...
Aging cell, 2019
2019
PGC-1α regulates mitochondrial calcium homeostasis, SR stress and cell death to mitigate skeletal muscle aging
JF Gill, J Delezie, G Santos, S McGuirk, S Schnyder, S Frank, M Rausch, ...
bioRxiv, 451229, 2018
2018
Student perspective of STEM education in Canada
C Cavanagh, L Crapper, K Dietrich, T Gruosso, C Gualtieri, YS Huang, ...
https://www.sp-exchange.ca/reports, 2016
2016
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