Richard B Kim
Zitiert von
Zitiert von
Membrane transporters in drug development
Nature reviews Drug discovery 9 (3), 215-236, 2010
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.
RB Kim, MF Fromm, C Wandel, B Leake, AJ Wood, DM Roden, ...
The Journal of clinical investigation 101 (2), 289-294, 1998
Identification of functionally variant MDR1 alleles among European Americans and African Americans
RB Kim, BF Leake, EF Choo, GK Dresser, SV Kubba, UI Schwarz, ...
Clinical Pharmacology & Therapeutics 70 (2), 189-199, 2001
Polymorphisms in Human MDR1 (P‐glycoprotein): Recent Advances and Clinical Relevance
C Marzolini, E Paus, T Buclin, RB Kim
Clinical Pharmacology & Therapeutics 75 (1), 13-33, 2004
SLC transporters as therapeutic targets: emerging opportunities
L Lin, SW Yee, RB Kim, KM Giacomini
Nature reviews Drug discovery 14 (8), 543-560, 2015
Pharmacogenetics of efavirenz and central nervous system side effects: an Adult AIDS Clinical Trials Group study
DW Haas, HJ Ribaudo, RB Kim, C Tierney, GR Wilkinson, RM Gulick, ...
Aids 18 (18), 2391-2400, 2004
Molecular basis of ethnic differences in drug disposition and response
HG Xie, RB Kim, AJJ Wood, CM Stein
Annual review of pharmacology and toxicology 41 (1), 815-850, 2001
Genetic determinants of response to warfarin during initial anticoagulation
UI Schwarz, MD Ritchie, Y Bradford, C Li, SM Dudek, A Frye-Anderson, ...
New England Journal of Medicine 358 (10), 999-1008, 2008
Polymorphisms in OATP-C: identification of multiple allelic variants associated with altered transport activity among European-and African-Americans
RG Tirona, BF Leake, G Merino, RB Kim
Journal of Biological Chemistry 276 (38), 35669-35675, 2001
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine
M Cvetkovic, B Leake, MF Fromm, GR Wilkinson, RB Kim
Drug metabolism and disposition 27 (8), 866-871, 1999
Fruit juices inhibit organic anion transporting polypeptide–mediated drug uptake to decrease the oral availability of fexofenadine
GK Dresser, DG Bailey, BF Leake, UI Schwarz, PA Dawson, DJ Freeman, ...
Clinical pharmacology & therapeutics 71 (1), 11-20, 2002
Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics
RH Ho, RG Tirona, BF Leake, H Glaeser, W Lee, CJ Lemke, Y Wang, ...
Gastroenterology 130 (6), 1793-1806, 2006
Transporters and drug therapy: implications for drug disposition and disease
RH Ho, RB Kim
Clinical Pharmacology & Therapeutics 78 (3), 260-277, 2005
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4
RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ...
Nature medicine 9 (2), 220-224, 2003
Drugs as P-glycoprotein substrates, inhibitors, and inducers
RB Kim
Drug metabolism reviews 34 (1-2), 47-54, 2002
Inhibition of P-glycoprotein–mediated drug transport: a unifying mechanism to explain the interaction between digoxin and quinidine
MF Fromm, RB Kim, CM Stein, GR Wilkinson, DM Roden
Circulation 99 (4), 552-557, 1999
Pharmacological inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain and testes
EF Choo, B Leake, C Wandel, H Imamura, AJJ Wood, GR Wilkinson, ...
Drug Metabolism and Disposition 28 (6), 655-660, 2000
Intestinal drug transporter expression and the impact of grapefruit juice in humans
H Glaeser, DG Bailey, GK Dresser, JC Gregor, UI Schwarz, JS McGrath, ...
Clinical Pharmacology & Therapeutics 81 (3), 362-370, 2007
The effect of common polymorphisms of the β2-adrenergic receptor on agonist-mediated vascular desensitization
V Dishy, GG Sofowora, HG Xie, RB Kim, DW Byrne, CM Stein, AJJ Wood
New England Journal of Medicine 345 (14), 1030-1035, 2001
CYP2C9 allelic variants: ethnic distribution and functional significance
HG Xie, HC Prasad, RB Kim, CM Stein
Advanced drug delivery reviews 54 (10), 1257-1270, 2002
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