Highly efficient Cas9-mediated gene drive for population modification of the malaria vector mosquito Anopheles stephensi VM Gantz, N Jasinskiene, O Tatarenkova, A Fazekas, VM Macias, E Bier, ... Proceedings of the National Academy of Sciences 112 (49), E6736-E6743, 2015 | 1120 | 2015 |
The mutagenic chain reaction: a method for converting heterozygous to homozygous mutations VM Gantz, E Bier Science 348 (6233), 442-444, 2015 | 673 | 2015 |
Safeguarding gene drive experiments in the laboratory OS Akbari, HJ Bellen, E Bier, SL Bullock, A Burt, GM Church, KR Cook, ... Science 349 (6251), 927-929, 2015 | 339 | 2015 |
Super-Mendelian inheritance mediated by CRISPR–Cas9 in the female mouse germline HA Grunwald, VM Gantz, G Poplawski, XRS Xu, E Bier, KL Cooper Nature 566 (7742), 105-109, 2019 | 244 | 2019 |
The dawn of active genetics VM Gantz, E Bier Bioessays 38 (1), 50-63, 2016 | 147 | 2016 |
Efficient population modification gene-drive rescue system in the malaria mosquito Anopheles stephensi A Adolfi, VM Gantz, N Jasinskiene, HF Lee, K Hwang, G Terradas, ... Nature communications 11 (1), 5553, 2020 | 132 | 2020 |
Gene editing technologies and applications for insects VM Gantz, OS Akbari Current opinion in insect science 28, 66-72, 2018 | 85 | 2018 |
Rules of the road for insect gene drive research and testing Z Adelman, O Akbari, J Bauer, E Bier, C Bloss, SR Carter, C Callender, ... Nature biotechnology 35 (8), 716-718, 2017 | 84 | 2017 |
Core commitments for field trials of gene drive organisms KC Long, L Alphey, GJ Annas, CS Bloss, KJ Campbell, J Champer, ... Science 370 (6523), 1417-1419, 2020 | 75 | 2020 |
Assessment of a split homing based gene drive for efficient knockout of multiple genes NP Kandul, J Liu, A Buchman, VM Gantz, E Bier, OS Akbari G3: Genes, Genomes, Genetics 10 (2), 827-837, 2020 | 68 | 2020 |
A transcomplementing gene drive provides a flexible platform for laboratory investigation and potential field deployment V López Del Amo, AL Bishop, HM Sánchez C, JB Bennett, X Feng, ... Nature Communications 11 (1), 352, 2020 | 66 | 2020 |
Efficient allelic-drive in Drosophila A Guichard, T Haque, M Bobik, XRS Xu, C Klanseck, RBS Kushwah, ... Nature communications 10 (1), 1640, 2019 | 62 | 2019 |
Active genetic neutralizing elements for halting or deleting gene drives XRS Xu, EA Bulger, VM Gantz, C Klanseck, SR Heimler, A Auradkar, ... Molecular cell 80 (2), 246-262. e4, 2020 | 54 | 2020 |
Small-molecule control of super-Mendelian inheritance in gene drives VL Del Amo, BS Leger, KJ Cox, S Gill, AL Bishop, GD Scanlon, JA Walker, ... Cell reports 31 (13), 2020 | 48 | 2020 |
CRISPR/Cas9 and active genetics-based trans-species replacement of the endogenous Drosophila kni-L2 CRM reveals unexpected complexity XRS Xu, VM Gantz, N Siomava, E Bier Elife 6, e30281, 2017 | 38 | 2017 |
Optimized CRISPR tools and site-directed transgenesis towards gene drive development in Culex quinquefasciatus mosquitoes X Feng, V López Del Amo, E Mameli, M Lee, AL Bishop, N Perrimon, ... Nature Communications 12 (1), 2960, 2021 | 28 | 2021 |
Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline AJ Weitzel, HA Grunwald, C Weber, R Levina, VM Gantz, SM Hedrick, ... PLoS biology 19 (12), e3001478, 2021 | 24 | 2021 |
Beyond the eye: Kynurenine pathway impairment causes midgut homeostasis dysfunction and survival and reproductive costs in blood-feeding mosquitoes V Bottino-Rojas, I Ferreira-Almeida, RD Nunes, X Feng, TB Pham, ... Insect Biochemistry and Molecular Biology 142, 103720, 2022 | 16 | 2022 |
Targeting double-strand break indel byproducts with secondary guide RNAs improves Cas9 HDR-mediated genome editing efficiencies Z Bodai, AL Bishop, VM Gantz, AC Komor Nature communications 13 (1), 2351, 2022 | 14 | 2022 |
Evaluation of Gene Knockouts by CRISPR as Potential Targets for the Genetic Engineering of the Mosquito Culex quinquefasciatus X Feng, L Kambic, JHK Nishimoto, FA Reed, JA Denton, JT Sutton, ... The CRISPR Journal 4 (4), 595-608, 2021 | 12* | 2021 |