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Joshua Levitz
Joshua Levitz
Associate Professor, Weill Cornell Medicine
Verified email at med.cornell.edu - Homepage
Title
Cited by
Cited by
Year
Glutamatergic signaling in the central nervous system: ionotropic and metabotropic receptors in concert
A Reiner, J Levitz
Neuron 98 (6), 1080-1098, 2018
5092018
A mechanism for tunable autoinhibition in the structure of a human Ca2+/calmodulin-dependent kinase II holoenzyme
LH Chao, MM Stratton, IH Lee, OS Rosenberg, J Levitz, DJ Mandell, ...
Cell 146 (5), 732-745, 2011
2782011
Optical control of metabotropic glutamate receptors
J Levitz, C Pantoja, B Gaub, H Janovjak, A Reiner, A Hoagland, ...
Nature neuroscience 16 (4), 507-516, 2013
2322013
Conformational dynamics of a class C G-protein-coupled receptor
R Vafabakhsh, J Levitz, EY Isacoff
Nature 524 (7566), 497-501, 2015
1762015
Mechanism of assembly and cooperativity of homomeric and heteromeric metabotropic glutamate receptors
J Levitz, C Habrian, S Bharill, Z Fu, R Vafabakhsh, EY Isacoff
Neuron 92 (1), 143-159, 2016
1622016
Restoration of high-sensitivity and adapting vision with a cone opsin
MH Berry, A Holt, A Salari, J Veit, M Visel, J Levitz, K Aghi, BM Gaub, ...
Nature communications 10 (1), 1221, 2019
1222019
Orthogonal optical control of a G protein-coupled receptor with a SNAP-tethered photochromic ligand
J Broichhagen, A Damijonaitis, J Levitz, KR Sokol, P Leippe, D Konrad, ...
ACS central science 1 (7), 383-393, 2015
1172015
Migraine-associated TRESK mutations increase neuronal excitability through alternative translation initiation and inhibition of TREK
P Royal, A Andres-Bilbe, PÁ Prado, C Verkest, B Wdziekonski, S Schaub, ...
Neuron 101 (2), 232-245. e6, 2019
1142019
Optical control of endogenous proteins with a photoswitchable conditional subunit reveals a role for TREK1 in GABAB signaling
G Sandoz, J Levitz, RH Kramer, EY Isacoff
Neuron 74 (6), 1005-1014, 2012
1132012
Two-photon brightness of azobenzene photoswitches designed for glutamate receptor optogenetics
EC Carroll, S Berlin, J Levitz, MA Kienzler, Z Yuan, D Madsen, DS Larsen, ...
Proceedings of the National Academy of Sciences 112 (7), E776-E785, 2015
982015
Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels
J Levitz, P Royal, Y Comoglio, B Wdziekonski, S Schaub, DM Clemens, ...
Proceedings of the National Academy of Sciences 113 (15), 4194-4199, 2016
812016
Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor
MH Berry, A Holt, J Levitz, J Broichhagen, BM Gaub, M Visel, C Stanley, ...
Nature communications 8 (1), 1862, 2017
802017
Optical control of dopamine receptors using a photoswitchable tethered inverse agonist
PC Donthamsetti, N Winter, M Schönberger, J Levitz, C Stanley, ...
Journal of the American Chemical Society 139 (51), 18522-18535, 2017
752017
Structural basis for KCTD-mediated rapid desensitization of GABAB signalling
S Zheng, N Abreu, J Levitz, AC Kruse
Nature 567 (7746), 127-131, 2019
732019
Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors
J Levitz, J Broichhagen, P Leippe, D Konrad, D Trauner, EY Isacoff
Proceedings of the National Academy of Sciences 114 (17), E3546-E3554, 2017
722017
Structural and biophysical mechanisms of class CG protein-coupled receptor function
A Ellaithy, J Gonzalez-Maeso, DA Logothetis, J Levitz
Trends in biochemical sciences 45 (12), 1049-1064, 2020
632020
Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO)
DM Barber, M Schönberger, J Burgstaller, J Levitz, CD Weaver, EY Isacoff, ...
Chemical science 7 (3), 2347-2352, 2016
592016
Phospholipase D2 specifically regulates TREK potassium channels via direct interaction and local production of phosphatidic acid
Y Comoglio, J Levitz, MA Kienzler, F Lesage, EY Isacoff, G Sandoz
Proceedings of the National Academy of Sciences 111 (37), 13547-13552, 2014
592014
Branched photoswitchable tethered ligands enable ultra-efficient optical control and detection of G protein-coupled receptors in vivo
A Acosta-Ruiz, VA Gutzeit, MJ Skelly, S Meadows, J Lee, P Parekh, ...
Neuron 105 (3), 446-463. e13, 2020
582020
Conformational pathway provides unique sensitivity to a synaptic mGluR
CH Habrian, J Levitz, V Vyklicky, Z Fu, A Hoagland, I McCort-Tranchepain, ...
Nature communications 10 (1), 5572, 2019
582019
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