Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis. I Hoffmann, PR Clarke, MJ Marcote, E Karsenti, G Draetta The EMBO journal 12 (1), 53-63, 1993 | 886 | 1993 |
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK LA Allan, N Morrice, S Brady, G Magee, S Pathak, PR Clarke Nature cell biology 5 (7), 647-654, 2003 | 604 | 2003 |
Purification and characterization of the AMP‐activated protein kinase: Copurification of acetyl‐CoA carboxylase kinase and 3‐hydroxy‐3‐methylglutaryl‐CoA reductase kinase … D Carling, PR Clarke, VA Zammit, DG Hardie European journal of biochemistry 186 (1‐2), 129-136, 1989 | 522 | 1989 |
Spatial and temporal coordination of mitosis by Ran GTPase PR Clarke, C Zhang Nature reviews Molecular cell biology 9 (6), 464-477, 2008 | 493 | 2008 |
Regulation of HMG‐CoA reductase: identification of the site phosphorylated by the AMP‐activated protein kinase in vitro and in intact rat liver. PR Clarke, DG Hardie The EMBO journal 9 (8), 2439-2446, 1990 | 386 | 1990 |
Phosphorylation of Mcl‐1 by CDK1–cyclin B1 initiates its Cdc20‐dependent destruction during mitotic arrest ME Harley, LA Allan, HS Sanderson, PR Clarke The EMBO journal 29 (14), 2407-2420, 2010 | 385 | 2010 |
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis LA Allan, PR Clarke Molecular cell 26 (2), 301-310, 2007 | 294 | 2007 |
Apoptosis and autophagy: regulation of caspase‐9 by phosphorylation LA Allan, PR Clarke The FEBS journal 276 (21), 6063-6073, 2009 | 269 | 2009 |
Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. PR Clarke, I Hoffmann, G Draetta, E Karsenti Molecular biology of the cell 4 (4), 397-411, 1993 | 251 | 1993 |
Chromatin-independent nuclear envelope assembly induced by Ran GTPase in Xenopus egg extracts C Zhang, PR Clarke Science 288 (5470), 1429-1432, 2000 | 248 | 2000 |
Regulation of apoptosis by BH3 domains in a cell-free system SC Cosulich, V Worrall, PJ Hedge, S Green, PR Clarke Current Biology 7 (12), 913-920, 1997 | 239 | 1997 |
Bcl-2 regulates a caspase-3/caspase-2 apoptotic cascade in cytosolic extracts E Swanton, P Savory, S Cosulich, P Clarke, P Woodman Oncogene 18 (10), 1781-1787, 1999 | 216 | 1999 |
Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts C Zhang, M Hughes, PR Clarke Journal of cell science 112 (14), 2453-2461, 1999 | 185 | 1999 |
Cell-cycle control in the face of damage–a matter of life or death PR Clarke, LA Allan Trends in cell biology 19 (3), 89-98, 2009 | 165 | 2009 |
Inhibition of the G2 DNA damage checkpoint and of protein kinases Chk1 and Chk2 by the marine sponge alkaloid debromohymenialdisine D Curman, B Cinel, DE Williams, N Rundle, WD Block, AA Goodarzi, ... Journal of Biological Chemistry 276 (21), 17914-17919, 2001 | 165 | 2001 |
Ran GTPase: a master regulator of nuclear structure and function during the eukaryotic cell division cycle? PR Clarke, C Zhang Trends in cell biology 11 (9), 366-371, 2001 | 161 | 2001 |
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine A Seifert, LA Allan, PR Clarke The FEBS journal 275 (24), 6268-6280, 2008 | 150 | 2008 |
Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells WJ Moore, C Zhang, PR Clarke Current biology 12 (16), 1442-1447, 2002 | 144 | 2002 |
Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c MC Martin, LA Allan, M Lickrish, C Sampson, N Morrice, PR Clarke Journal of Biological Chemistry 280 (15), 15449-15455, 2005 | 133 | 2005 |
Evidence for a protein kinase cascade in higher plants: 3‐hydroxy‐3‐methylglutaryl‐CoA reductase kinase RW Mackintosh, SP Davies, PR Clarke, J Weekes, JG Gillespie, BJ Gibb, ... European Journal of Biochemistry 209 (3), 923-931, 1992 | 130 | 1992 |