Toni T. Seppälä
Toni T. Seppälä
University of Tampere
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Cancer incidence and survival in Lynch syndrome patients receiving colonoscopic and gynaecological surveillance: first report from the prospective Lynch syndrome database
P Møller, T Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ...
Gut 66 (3), 464-472, 2017
Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database
P Møller, TT Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ...
Gut 67 (7), 1306-1316, 2018
Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database
M Dominguez-Valentin, JR Sampson, TT Seppälä, SW Ten Broeke, ...
Genetics in Medicine 22 (1), 15-25, 2020
Guidelines for the management of hereditary colorectal cancer from the British Society of Gastroenterology (BSG)/Association of Coloproctology of Great Britain and Ireland …
KJ Monahan, N Bradshaw, S Dolwani, B Desouza, MG Dunlop, JE East, ...
Gut 69 (3), 411-444, 2020
Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind …
J Burn, H Sheth, F Elliott, L Reed, F Macrae, JP Mecklin, G Möslein, ...
The Lancet 395 (10240), 1855-1863, 2020
CSF biomarkers for Alzheimer disease correlate with cortical brain biopsy findings
TT Seppälä, O Nerg, AM Koivisto, J Rummukainen, L Puli, H Zetterberg, ...
Neurology 78 (20), 1568-1575, 2012
Combination of microsatellite instability and BRAF mutation status for subtyping colorectal cancer
TT Seppälä, JP Böhm, M Friman, L Lahtinen, VMJ Väyrynen, TKE Liipo, ...
British journal of cancer 112 (12), 1966-1975, 2015
Incidence of and survival after subsequent cancers in carriers of pathogenic MMR variants with previous cancer: a report from the prospective Lynch syndrome database
P Møller, T Seppälä, I Bernstein, E Holinski-Feder, P Sala, DG Evans, ...
Gut 66 (9), 1657-1664, 2017
European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender
TT Seppälä, A Latchford, I Negoi, A Sampaio Soares, ...
British Journal of Surgery 108 (5), 484-498, 2021
Characteristics of early-onset vs late-onset colorectal cancer: a review
R Collaborative, AM Zaborowski, A Abdile, M Adamina, F Aigner, ...
JAMA surgery 156 (9), 865-874, 2021
No difference in colorectal cancer incidence or stage at detection by colonoscopy among 3 countries with different Lynch syndrome surveillance policies
C Engel, HF Vasen, T Seppälä, S Aretz, M Bigirwamungu-Bargeman, ...
Gastroenterology 155 (5), 1400-1409. e2, 2018
Cerebrospinal fluid biomarker and brain biopsy findings in idiopathic normal pressure hydrocephalus
OT Pyykkö, M Lumela, J Rummukainen, O Nerg, TT Seppälä, SK Herukka, ...
PloS one 9 (3), e91974, 2014
Plasma Aβ42 and Aβ40 as markers of cognitive change in follow-up: a prospective, longitudinal, population-based cohort study
TT Seppälä, SK Herukka, T Hänninen, S Tervo, M Hallikainen, H Soininen, ...
Journal of Neurology, Neurosurgery & Psychiatry 81 (10), 1123-1127, 2010
The shared frameshift mutation landscape of microsatellite-unstable cancers suggests immunoediting during tumor evolution
A Ballhausen, MJ Przybilla, M Jendrusch, S Haupt, E Pfaffendorf, ...
Nature communications 11 (1), 4740, 2020
Genetic and epigenetic characteristics of inflammatory bowel Disease–Associated colorectal cancer
K Rajamäki, A Taira, R Katainen, N Välimäki, A Kuosmanen, RM Plaketti, ...
Gastroenterology 161 (2), 592-607, 2021
Longitudinal changes of CSF biomarkers in Alzheimer's disease
TT Seppälä, AM Koivisto, P Hartikainen, S Helisalmi, H Soininen, ...
Journal of Alzheimer's Disease 25 (4), 583-594, 2011
Immunoscore in mismatch repair‐proficient and‐deficient colon cancer
EV Wirta, T Seppälä, M Friman, J Väyrynen, M Ahtiainen, H Kautiainen, ...
The Journal of Pathology: Clinical Research 3 (3), 203-213, 2017
Colorectal cancer incidence in path_MLH1 carriers subjected to different follow-up protocols: a Prospective Lynch Syndrome Database report
T Seppälä, K Pylvänäinen, DG Evans, H Järvinen, L Renkonen-Sinisalo, ...
Hereditary cancer in clinical practice 15, 1-10, 2017
Patient-derived organoid pharmacotyping is a clinically tractable strategy for precision medicine in pancreatic cancer
TT Seppälä, JW Zimmerman, E Sereni, D Plenker, R Suri, N Rozich, ...
Annals of surgery 272 (3), 427, 2020
Associations of pathogenic variants in MLH1, MSH2, and MSH6 with risk of colorectal adenomas and tumors and with somatic mutations in patients with Lynch syndrome
C Engel, A Ahadova, TT Seppälä, S Aretz, M Bigirwamungu-Bargeman, ...
Gastroenterology 158 (5), 1326-1333, 2020
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