Jason Young
Jason Young
Verified email at mcgill.ca
TitleCited byYear
Pathways of chaperone-mediated protein folding in the cytosol
JC Young, VR Agashe, K Siegers, FU Hartl
Nature reviews Molecular cell biology 5 (10), 781-791, 2004
Hsp90: a specialized but essential protein-folding tool
JC Young, I Moarefi, FU Hartl
The Journal of cell biology 154 (2), 267, 2001
Molecular chaperones Hsp90 and Hsp70 deliver preproteins to the mitochondrial import receptor Tom70
JC Young, NJ Hoogenraad, FU Hartl
Cell 112 (1), 41-50, 2003
More than folding: localized functions of cytosolic chaperones
JC Young, JM Barral, FU Hartl
Trends in biochemical sciences 28 (10), 541-547, 2003
Peripheral protein quality control removes unfolded CFTR from the plasma membrane
T Okiyoneda, H Barrière, M Bagdány, WM Rabeh, K Du, J Höhfeld, ...
Science 329 (5993), 805-810, 2010
Specific binding of tetratricopeptide repeat proteins to the C-terminal 12-kDa domain of hsp90
JC Young, WMJ Obermann, FU Hartl
Journal of Biological Chemistry 273 (29), 18007-18010, 1998
Polypeptide release by Hsp90 involves ATP hydrolysis and is enhanced by the co‐chaperone p23
JC Young, FU Hartl
The EMBO journal 19 (21), 5930-5940, 2000
Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange
Y Shomura, Z Dragovic, HC Chang, N Tzvetkov, JC Young, JL Brodsky, ...
Molecular cell 17 (3), 367-379, 2005
Mechanisms of the Hsp70 chaperone system
JC Young
Biochemistry and Cell Biology 88 (2), 291-300, 2010
In vitro evidence that hsp90 contains two independent chaperone sites
JC Young, C Schneider, FU Hartl
FEBS letters 418 (1-2), 139-143, 1997
Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system
A Brychzy, T Rein, KF Winklhofer, FU Hartl, JC Young, WMJ Obermann
The EMBO journal 22 (14), 3613-3623, 2003
Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones
BM Abell, C Rabu, P Leznicki, JC Young, S High
Journal of cell science 120 (10), 1743-1751, 2007
Prediction of novel Bag-1 homologs based on structure/function analysis identifies Snl1p as an Hsp70 co-chaperone in Saccharomyces cerevisiae
H Sondermann, AK Ho, LL Listenberger, K Siegers, I Moarefi, SR Wente, ...
Journal of biological chemistry 277 (36), 33220-33227, 2002
Regulation of activation-induced deaminase stability and antibody gene diversification by Hsp90
A Orthwein, AM Patenaude, EB Affar, A Lamarre, JC Young, JM Di Noia
Journal of Experimental Medicine 207 (12), 2751-2765, 2010
Hsp90 functions in the targeting and outer membrane translocation steps of Tom70-mediated mitochondrial import
ACY Fan, MK Bhangoo, JC Young
Journal of Biological Chemistry 281 (44), 33313-33324, 2006
The heat shock protein 90-targeting drug cisplatin selectively inhibits steroid receptor activation
MC Rosenhagen, C Sõti, U Schmidt, GM Wochnik, FU Hartl, F Holsboer, ...
Molecular Endocrinology 17 (10), 1991-2001, 2003
Functional divergence between co-chaperones of Hsc70
S Tzankov, MJH Wong, K Shi, C Nassif, JC Young
Journal of Biological Chemistry 283 (40), 27100-27109, 2008
Dynamic comparisons of piezoelectric ejecta diagnostics
WT Buttler, MB Zellner, RT Olson, PA Rigg, RS Hixson, JE Hammerberg, ...
Journal of applied physics 101 (6), 063547, 2007
Lung volume reduction surgery (LVRS) for chronic obstructive pulmonary disease (COPD) with underlying severe emphysema
J Young, A Fry-Smith, C Hyde
Thorax 54 (9), 779-789, 1999
Multiple 40-kDa heat-shock protein chaperones function in Tom70-dependent mitochondrial import
MK Bhangoo, S Tzankov, ACY Fan, K Dejgaard, DY Thomas, JC Young
Molecular biology of the cell 18 (9), 3414-3428, 2007
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