Directional R-loop formation by the CRISPR-Cas surveillance complex cascade provides efficient off-target site rejection M Rutkauskas, T Sinkunas, I Songailiene, MS Tikhomirova, V Siksnys, ... Cell reports 10 (9), 1534-1543, 2015 | 180 | 2015 |
Single-molecule insight into target recognition by CRISPR–Cas complexes M Rutkauskas, A Krivoy, MD Szczelkun, C Rouillon, R Seidel Methods in enzymology 582, 239-273, 2017 | 27 | 2017 |
Primed CRISPR adaptation in Escherichia coli cells does not depend on conformational changes in the Cascade effector complex detected in Vitro A Krivoy, M Rutkauskas, K Kuznedelov, O Musharova, C Rouillon, ... Nucleic acids research 46 (8), 4087-4098, 2018 | 26 | 2018 |
Decision-making in Cascade complexes harboring crRNAs of altered length I Songailiene, M Rutkauskas, T Sinkunas, E Manakova, S Wittig, ... Cell reports 28 (12), 3157-3166. e4, 2019 | 13 | 2019 |
Probing the stability of the SpCas9–DNA complex after cleavage P Aldag, F Welzel, L Jakob, A Schmidbauer, M Rutkauskas, F Fettes, ... Nucleic Acids Research 49 (21), 12411-12421, 2021 | 12 | 2021 |
Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI G Tamulaitis, M Rutkauskas, M Zaremba, S Grazulis, G Tamulaitiene, ... Nucleic acids research 43 (16), 8100-8110, 2015 | 11 | 2015 |
A quantitative model for the dynamics of target recognition and off-target rejection by the CRISPR-Cas Cascade complex M Rutkauskas, I Songailiene, P Irmisch, FE Kemmerich, T Sinkunas, ... Nature communications 13 (1), 7460, 2022 | 9 | 2022 |
The energy landscape for R-loop formation by the CRISPR–Cas Cascade complex DJ Kauert, J Madariaga-Marcos, M Rutkauskas, A Wulfken, I Songailiene, ... Nature structural & molecular biology 30 (7), 1040-1047, 2023 | 6 | 2023 |
Dynamic interplay between target search and recognition for a Type I CRISPR-Cas system P Aldag, M Rutkauskas, J Madariaga-Marcos, I Songailiene, T Sinkunas, ... Nature communications 14 (1), 3654, 2023 | 3 | 2023 |
Modelling DNA-strand displacement reactions from single base-pair steps to reaction networks P Irmisch, M Rutkauskas, E Del Grosso, F Ricci, R Seidel Biophysical Journal 121 (3), 170a-171a, 2022 | 3 | 2022 |
Dynamic interplay between target search and recognition for the Cascade surveillance complex of type IE CRISPR-Cas systems P Aldag, M Rutkauskas, J Madariaga-Marcos, I Songailiene, T Sinkunas, ... bioRxiv, 2022.12. 18.520913, 2022 | 2 | 2022 |
Energy landscapes of CRISPR/Cas R-loop formation from ultrafast twist measurements JM Marcos, DJ Kauert, M Rutkauskas, A Wulfken, I Songaliene, ... Biophysical Journal 121 (3), 283a, 2022 | | 2022 |
Dissecting the Target Recognition by CRISPR/Cas Effector Complexes with Ultrafast Twist Measurements JM Marcos, DJ Kauert, M Rutkauskas, A Wulfken, I Songaliene, ... Biophysical Journal 120 (3), 93a-94a, 2021 | | 2021 |
A Simple Thermodynamic Model for DNA-Strand Displacement Reactions in Presence of Base-Pair Mismatches P Irmisch, M Rutkauskas, R Seidel Biophysical Journal 118 (3), 66a, 2020 | | 2020 |
Investigating and Modelling the Target Recognition Dynamics of the CRISPR-Cas Surveillance Complex Cascade M Rutkauskas, T Sinkūnas, I Songailiene, V Siksnys, R Seidel Biophysical Journal 114 (3), 194a, 2018 | | 2018 |
Target recognition by Cascade complexes bearing altered length crRNA I Songailiene, M Rutkauskas, T Sinkunas, S Zurhorst, C Schmidt, R Seidel, ... FEBS JOURNAL 284, 167-167, 2017 | | 2017 |
Dynamic DNA Target Proofreading in a CRISPR-Cas System M Rutkauskas, T Sinkunas, MS Tikhomirova, V Siksnys, R Seidel Biophysical Journal 108 (2), 206a, 2015 | | 2015 |
From monomer to tetramer: crystal structures of related restriction endonucleases AgeI and BsaWI G Tamulaitiene, V Jovaisaite, M Rutkauskas, G Tamulaitis, V Siksnys FEBS JOURNAL 281, 742-742, 2014 | | 2014 |
Supplementary data to: Functional significance of protein assemblies predicted by the crystal structure of the restriction endonuclease BsaWI G Tamulaitis, M Rutkauskas, M Zaremba, S Grazulis, G Tamulaitiene, ... | | |