Clifford Lowell
Clifford Lowell
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The multifaceted functions of neutrophils
TN Mayadas, X Cullere, CA Lowell
Annual review of pathology 9, 181, 2014
A critical role for Syk in signal transduction and phagocytosis mediated by Fcγ receptors on macrophages
MT Crowley, PS Costello, CJ Fitzer-Attas, M Turner, F Meng, C Lowell, ...
The Journal of experimental medicine 186 (7), 1027-1039, 1997
The ins and outs of leukocyte integrin signaling
CL Abram, CA Lowell
Annual review of immunology 27, 339-362, 2009
Transfusion-related acute lung injury: incidence and risk factors
P Toy, O Gajic, P Bacchetti, MR Looney, MA Gropper, R Hubmayr, ...
Blood, The Journal of the American Society of Hematology 119 (7), 1757-1767, 2012
Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production
DM Underhill, E Rossnagle, CA Lowell, RM Simmons
Blood 106 (7), 2543-2550, 2005
Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation
VWF Chan, F Meng, P Soriano, AL DeFranco, CA Lowell
Immunity 7 (1), 69-81, 1997
The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
A Mócsai, MB Humphrey, JAG Van Ziffle, Y Hu, A Burghardt, SC Spusta, ...
Proceedings of the National Academy of Sciences 101 (16), 6158-6163, 2004
Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk
F Abtahian, A Guerriero, E Sebzda, MM Lu, R Zhou, A Mocsai, EE Myers, ...
Science 299 (5604), 247-251, 2003
Lipopolysaccharide (LPS)-induced macrophage activation and signal transduction in the absence of Src-family kinases Hck, Fgr, and Lyn
F Meng, CA Lowell
The Journal of experimental medicine 185 (9), 1661-1670, 1997
Coordinate interactions of Csk, Src, and Syk kinases with αIIbβ3 initiate integrin signaling to the cytoskeleton
A Obergfell, K Eto, A Mocsai, C Buensuceso, SL Moores, JS Brugge, ...
The Journal of cell biology 157 (2), 265-275, 2002
Syk is required for integrin signaling in neutrophils
A Mócsai, M Zhou, F Meng, VL Tybulewicz, CA Lowell
Immunity 16 (4), 547-558, 2002
Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury
MR Looney, JX Nguyen, Y Hu, JA Van Ziffle, CA Lowell, MA Matthay
The Journal of clinical investigation 119 (11), 3450-3461, 2009
Deficiency of Src family kinases p59/61hck and p58c-fgr results in defective adhesion-dependent neutrophil functions.
CA Lowell, L Fumagalli, G Berton
The Journal of cell biology 133 (4), 895-910, 1996
Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice
CL Abram, GL Roberge, Y Hu, CA Lowell
Journal of immunological methods 408, 89-100, 2014
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifs
A Mócsai, CL Abram, Z Jakus, Y Hu, LL Lanier, CA Lowell
Nature immunology 7 (12), 1326-1333, 2006
Essential role of Src-family protein tyrosine kinases in NF-κB activation during B cell development
K Saijo, C Schmedt, I Su, H Karasuyama, CA Lowell, M Reth, T Adachi, ...
Nature immunology 4 (3), 274-279, 2003
Knockouts of Src-family kinases: stiff bones, wimpy T cells, and bad memories.
CA Lowell, P Soriano
Genes & development 10 (15), 1845-1857, 1996
Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12
JA Hamerman, NK Tchao, CA Lowell, LL Lanier
Nature immunology 6 (6), 579-586, 2005
Neutrophils and their Fcγ receptors are essential in a mouse model of transfusion-related acute lung injury
MR Looney, X Su, JA Van Ziffle, CA Lowell, MA Matthay
The Journal of clinical investigation 116 (6), 1615-1623, 2006
A β1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration
F Meng, CA Lowell
The EMBO journal 17 (15), 4391-4403, 1998
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