| Toll-like receptor 4-dependent activation of dendritic cells by β-defensin 2 A Biragyn, PA Ruffini, CA Leifer, E Klyushnenkova, A Shakhov, O Chertov, ... Science 298 (5595), 1025-1029, 2002 | 1228 | 2002 |
| Leucine-rich repeats and pathogen recognition in Toll-like receptors JK Bell, GED Mullen, CA Leifer, A Mazzoni, DR Davies, DM Segal Trends in immunology 24 (10), 528-533, 2003 | 1014 | 2003 |
| TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis A Bafica, CA Scanga, CG Feng, C Leifer, A Cheever, A Sher The Journal of experimental medicine 202 (12), 1715-1724, 2005 | 836 | 2005 |
| Cutting edge: role of Toll-like receptor 9 in CpG DNA-induced activation of human cells F Takeshita, CA Leifer, I Gursel, KJ Ishii, S Takeshita, M Gursel, ... The Journal of Immunology 167 (7), 3555-3558, 2001 | 780 | 2001 |
| FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway E Gulbins, R Bissonnette, A Mahboubi, S Martin, W Nishloka, T Brunner, ... Immunity 2 (4), 341-351, 1995 | 494 | 1995 |
| TLR9 is localized in the endoplasmic reticulum prior to stimulation CA Leifer, MN Kennedy, A Mazzoni, CW Lee, MJ Kruhlak, DM Segal The journal of immunology 173 (2), 1179-1183, 2004 | 412 | 2004 |
| MARCO, TLR2, and CD14 Are Required for Macrophage Cytokine Responses to Mycobacterial Trehalose Dimycolate and Mycobacterium tuberculosis DME Bowdish, K Sakamoto, MJ Kim, M Kroos, S Mukhopadhyay, ... PLoS pathogens 5 (6), e1000474, 2009 | 389 | 2009 |
| The role of MyD88 and TLR4 in the LPS-mimetic activity of taxol byrd-leifer Eur J Immunol 31 (8), 2448-2457, 2001 | 373 | 2001 |
| Molecular mechanisms of regulation of Toll-like receptor signaling CA Leifer, AE Medvedev Journal of Leucocyte Biology 100 (5), 927-941, 2016 | 268 | 2016 |
| Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide Byrd, Bornmann, Erdjument-Bromage, Tempst, Pavletich, Rosen, Nathan, ... Proc Natl Acad Sci U S A 96 (10), 5645-5650, 1999 | 264 | 1999 |
| Genetic diversity of Toxoplasma gondii isolates from chickens from Brazil JP Dubey, GV Velmurugan, A Chockalingam, HFJ Pena, LN De Oliveira, ... Veterinary parasitology 157 (3-4), 299-305, 2008 | 149 | 2008 |
| A complex of soluble MD-2 and lipopolysaccharide serves as an activating ligand for Toll-like receptor 4 MN Kennedy, GED Mullen, CA Leifer, CW Lee, A Mazzoni, KN Dileepan, ... Journal of Biological Chemistry 279 (33), 34698-34704, 2004 | 143 | 2004 |
| TLR9 traffics through the Golgi complex to localize to endolysosomes and respond to CpG DNA A Chockalingam, JC Brooks, JL Cameron, LK Blum, CA Leifer Immunology and cell biology 87 (3), 209-217, 2009 | 139 | 2009 |
| Dendritic cell modulation by mast cells controls the Th1/Th2 balance in responding T cells A Mazzoni, RP Siraganian, CA Leifer, DM Segal The Journal of Immunology 177 (6), 3577-3581, 2006 | 132 | 2006 |
| Inhibition of TLR3 and TLR4 function and expression in human dendritic cells by helminth parasites RT Semnani, PG Venugopal, CA Leifer, S Mostböck, H Sabzevari, ... Blood, The Journal of the American Society of Hematology 112 (4), 1290-1298, 2008 | 120 | 2008 |
| Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice CG Rappazzo, HC Watkins, CM Guarino, A Chau, JL Lopez, MP DeLisa, ... Vaccine 34 (10), 1252-1258, 2016 | 116 | 2016 |
| Cytoplasmic targeting motifs control localization of toll-like receptor 9 CA Leifer, JC Brooks, K Hoelzer, J Lopez, MN Kennedy, A Mazzoni, ... Journal of biological chemistry 281 (46), 35585-35592, 2006 | 109 | 2006 |
| Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent LY Huang, J Aliberti, CA Leifer, DM Segal, A Sher, DT Golenbock, ... The Journal of Immunology 171 (3), 1441-1446, 2003 | 99 | 2003 |
| The role of disulfide bonds in the assembly and function of MD-2 GED Mullen, MN Kennedy, A Visintin, A Mazzoni, CA Leifer, DR Davies, ... Proceedings of the National Academy of Sciences 100 (7), 3919-3924, 2003 | 97 | 2003 |
| CpG DNA: recognition by and activation of monocytes DM Klinman, F Takeshita, I Gursel, C Leifer, KJ Ishii, D Verthelyi, M Gursel Microbes and infection 4 (9), 897-901, 2002 | 97 | 2002 |
